A study on oxygen saturation images constructed from the skin tissue of human hand

Under the irradiation of lights of two different wavelengths, the skin image of human hand can be obtained and roughly applied to construct the oxygen saturation image of skin tissue. The penetration (skin) depth of incident light increases with increasing wavelength between 350 to 1000 nm, and the deoxy-hemoglobin (Hb) and oxy-hemoglobin (HbO2) has a relatively high absorptivity in visible and near-infrared (NIR) spectrum, respectively; therefore, the intensity of diffuse reflected images of skin can be used to compute the oxygen saturation images of skin tissue. In the experiment, three LED light sources (red - 660 nm, NIR - 890 and 940 nm) were applied to construct the oxygen saturation images of skin tissue. The experiments show the oxygen saturation ranging from 84.69 to 88.79 % at the wrist and from 78.09 to 81.81 % at the back of hand when the skin tissue is irradiated by 660 and 890 nm LED light. The results not only could provide the distribution of oxygen saturation but also similar to the multi-spectral imaging method. In the future, the above result can be compared to that of transcutaneous oxygen pressure measurement (TcPO2), and provide a good reference to build the relationship between the oxygen saturation and healthy index for cardiovascular system in clinical diagnosis.

[1]  D. Abásolo,et al.  Nonlinear measure of synchrony between blood oxygen saturation and heart rate from nocturnal pulse oximetry in obstructive sleep apnoea syndrome , 2009, Physiological measurement.

[2]  Takuo Aoyagi,et al.  Pulse oximetry: its invention, theory, and future , 2003, Journal of Anesthesia.

[3]  H W Jongsma,et al.  Intrapartum fetal pulse oximetry: fetal oxygen saturation trends during labor and relation to delivery outcome. , 1994, American journal of obstetrics and gynecology.

[4]  W. Zijlstra,et al.  Absorption spectra of human fetal and adult oxyhemoglobin, de-oxyhemoglobin, carboxyhemoglobin, and methemoglobin. , 1991, Clinical chemistry.

[5]  Chun-Li Chang,et al.  The image analysis of skin tissue irradiated with difference wavelengths of LED sources , 2012, 2012 IEEE International Instrumentation and Measurement Technology Conference Proceedings.

[6]  R. Anderson,et al.  The optics of human skin. , 1981, The Journal of investigative dermatology.

[7]  M Itoh,et al.  Melanin and blood concentration in a human skin model studied by multiple regression analysis: assessment by Monte Carlo simulation , 2001, Physics in medicine and biology.

[8]  I. Meglinski,et al.  Quantitative assessment of skin layers absorption and skin reflectance spectra simulation in the visible and near-infrared spectral regions. , 2002, Physiological measurement.

[9]  Robert L. Cook,et al.  A Reflectance Model for Computer Graphics , 1987, TOGS.

[10]  Shu-Jung Chen,et al.  A new oxygen saturation images of iris tissue , 2010, 2010 IEEE Sensors.

[11]  Norimichi Tsumura,et al.  Mapping Pigmentation in Human Skin by Multi-Visible-Spectral Imaging by Inverse Optical Scattering Technique , 2000, Color Imaging Conference.