Antibacterial Activities of Syzygium aromaticum oil Against Local Clinical Pathogenic Bacteria

Eighteen bacterial isolates gram negative and gram positive were collected from King Fahd central hospital, Jazan region, Saudi Arabia. Four of these isolates belonging to Pseudomonas aeruginosa, three to Acintobacter baumanni and Klebsiella Pneumonia, two to Methicillin-resistant Staphylococcus aureus (MRSA) and E. coli, and one isolate to Enterobacter sp., E. aerogenes, Staphylococcus capitis and S. epidermis. Bacterial isolates were isolated from different sources e.g., blood, swab, throat, trachea, urine, wound. The antimicrobial activity of four plant oils; cloves (Syzygium aromaticum), ginger (Zingiber officinale), camphor (Cinnamomum camphora), and cinnamon (Cinnamomum verum) were obtained from the local market were evaluated on twelve sensitive and resistant isolates of the collected bacteria. Clove oil showed highest antimicrobial potential on different bacterial isolates (MICs ranged from 0.3125 to 3.75 μg/ml). The antimicrobial activity of clove oil was evaluated alone or incombination with 10g Gentamycin or 5g Rifampicin, antibiotics on both gram-negative and gram-positive bacteria. Association of antibiotics and clove oil showed synergistic antibacterial activity against tested bacteria.