HYBRID COMPUTATIONAL PHANTOMS REPRESENTING THE REFERENCE ADULT MALE AND ADULT FEMALE: CONSTRUCTION AND APPLICATIONS FOR RETROSPECTIVE DOSIMETRY

AbstractCurrently, two classes of computational phantoms have been developed for dosimetry calculation: (1) stylized (or mathematical) and (2) voxel (or tomographic) phantoms describing human anatomy through mathematical surface equations and 3D voxel matrices, respectively. Mathematical surface equations in stylized phantoms are flexible, but the resulting anatomy is not as realistic. Voxel phantoms display far better anatomical realism, but they are limited in terms of their ability to alter organ shape, position, and depth, as well as body posture. A new class of computational phantoms called hybrid phantoms takes advantage of the best features of stylized and voxel phantoms—flexibility and anatomical realism, respectively. In the current study, hybrid computational phantoms representing the adult male and female reference anatomy and anthropometry are presented. These phantoms serve as the starting framework for creating patient or worker sculpted whole-body phantoms for retrospective dose reconstruction. Contours of major organs and tissues were converted or segmented from computed tomography images of a 36-y-old Korean volunteer and a 25-y-old U.S. female patient, respectively, with supplemental high-resolution CT images of the cranium. Polygon mesh models for the major organs and tissues were reconstructed and imported into Rhinoceros™ for non-uniform rational B-spline (NURBS) surface modeling. The resulting NURBS/polygon mesh models representing body contour and internal anatomy were matched to anthropometric data and reference organ mass data provided by Centers for Disease Control and Prevention and International Commission on Radiation Protection, respectively. Finally, two hybrid adult male and female phantoms were completed where a total of eight anthropometric data categories were matched to standard values within 4% and organ volumes matched to ICRP data within 1% with the exception of total skin. The hybrid phantoms were voxelized from the NURBS phantoms at resolutions of 0.158 × 0.158 × 0.158 cm3 and 0.126 × 0.126 × 0.126 cm3 for the male and female, respectively. To highlight the flexibility of the hybrid phantoms, graphical displays are given of (1) underweight and overweight adult male phantoms, (2) a sitting position for the adult female phantom, and (3) extraction and higher-resolution voxelization of the small intestine for localized dosimetry of mucosal and stem cell layers. These phantoms are used to model radioactively contaminated individuals and to then assess time-dependent detector count rate thresholds corresponding to 50, 250, and 500 mSv effective dose, as might be needed during in-field radiological triage by first responders or first receivers.

[1]  Deanna Hasenauer,et al.  Hybrid computational phantoms of the male and female newborn patient: NURBS-based whole-body models , 2007, Physics in medicine and biology.

[2]  Choonsik Lee,et al.  GUIDANCE ON THE USE OF HANDHELD SURVEY METERS FOR RADIOLOGICAL TRIAGE: TIME-DEPENDENT DETECTOR COUNT RATES CORRESPONDING TO 50, 250, AND 500 mSV EFFECTIVE DOSE FOR ADULT MALES AND ADULT FEMALES , 2012, Health physics.

[3]  Les A. Piegl,et al.  On NURBS: A Survey , 2004 .

[4]  J. W. Vieira,et al.  All about FAX: a Female Adult voXel phantom for Monte Carlo calculation in radiation protection dosimetry. , 2003, Physics in medicine and biology.

[5]  M. Ljungberg,et al.  A dosimetry model for the small intestine incorporating intestinal wall activity and cross-doses. , 2002, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[6]  Robert A. Walker,et al.  Anthropometric Survey of U.S. Army Personnel: Summary Statistics, Interim Report for 1988 , 1989 .

[7]  Martin Caon,et al.  Voxel-based computational models of real human anatomy: a review , 2004, Radiation and environmental biophysics.

[8]  Daniel Lodwick,et al.  Hybrid computational phantoms of the 15-year male and female adolescent: applications to CT organ dosimetry for patients of variable morphometry. , 2008, Medical physics.

[9]  Chengyu Shi,et al.  A boundary-representation method for designing whole-body radiation dosimetry models: pregnant females at the ends of three gestational periods—RPI-P3, -P6 and -P9 , 2007, Physics in medicine and biology.

[10]  J. Valentin Basic anatomical and physiological data for use in radiological protection: reference values , 2002, Annals of the ICRP.

[11]  Keith F. Eckerman,et al.  Mathematical models and specific absorbed fractions of photon energy in the nonpregnant adult female and at the end of each trimester of pregnancy , 1995 .

[12]  R. Olsher,et al.  Application of a sitting MIRD phantom for effective dose calculations. , 2005, Radiation protection dosimetry.

[13]  N Petoussi-Henss,et al.  Organ dose conversion coefficients for voxel models of the reference male and female from idealized photon exposures , 2007, Physics in medicine and biology.

[14]  Habib Zaidi,et al.  Computational anthropomorphic models of the human anatomy: the path to realistic Monte Carlo modeling in radiological sciences. , 2007, Annual review of biomedical engineering.

[15]  N. Bayley,et al.  Growth in head circumference from birth through young adulthood. , 1962, Child development.

[16]  D. Manocha,et al.  Development and application of the new dynamic Nurbs-based Cardiac-Torso (NCAT) phantom. , 2001 .

[17]  G Gualdrini,et al.  An improved MCNP version of the NORMAN voxel phantom for dosimetry studies , 2005, Physics in medicine and biology.

[18]  R. Sievert,et al.  Book Reviews : Recommendations of the International Commission on Radiological Protection (as amended 1959 and revised 1962). I.C.R.P. Publication 6. 70 pp. PERGAMON PRESS. Oxford, London and New York, 1964. £1 5s. 0d. [TB/54] , 1964 .

[19]  K. F. Eckerman,et al.  Specific absorbed fractions of energy at various ages from internal photon sources: 6, Newborn , 1987 .

[20]  K. Eckerman,et al.  Development of PIMAL: Mathematical Phantom with Moving Arms and Legs , 2007 .

[21]  J. W. Vieira,et al.  All about FAX: a Female Adult voXel phantom for Monte Carlo calculation in radiation protection dosimetry , 2004, Physics in medicine and biology.