Regional skin temperatures associated with total sympathetic blockade in conscious dogs.

Multiple regional skin temperatures were measured continuously before and after complete sympathetic nerve block by extradural anaesthesia in conscious dogs in environmental temperatures slightly below (22.4 (SEM 0.4) degrees C) and slightly above (27.2 (0.4) degrees C) the thermoneutral range. In the cold environment, skin temperature increased in the distal (+2.13 degrees C, P less than 0.001) and proximal (+1.1 degrees C, P less than 0.02) front limbs and distal (+3.25 degrees C, P less than 0.001) and proximal (+1.72 degrees C, P less than 0.001) hind limbs, but decreased on the chest (-0.83 degrees C, P less than 0.01) and abdomen (-0.67 degrees C, P less than 0.002). Similar changes (all significant) were seen in the warm environment, although the effects were smaller. Rectal temperature did not change during the experiments. Arterial pressure decreased in both groups after denervation, but was the same in the denervated state regardless of ambient temperature. Our results are incompatible with increased sympathetic discharge from unblocked regions being a dominant factor in the decrease in trunk skin temperature above and within the analgesic areas, and demonstrate a substantial contribution of the sympathetic nervous system to the maintenance of the normal skin temperature gradient along the long axis of the body.

[1]  J. Johnson,et al.  Nonthermoregulatory control of human skin blood flow. , 1986, Journal of applied physiology.

[2]  D P Chamberlain,et al.  Changes in the Skin Temperature of the Trunk and Their Relationship to Sympathetic Blockade during Spinal Anesthesia , 1986, Anesthesiology.

[3]  J. Arndt,et al.  Peridural Anesthesia and the Distribution of Blood in Supine Humans , 1985, Anesthesiology.

[4]  K. Samii,et al.  Effects of Epidural Anesthesia on Catecholamines, Renin Activity, and Vasopressin Changes Induced by Tilt in Elderly Men , 1985, Anesthesiology.

[5]  M. Bengtsson.  Changes in Skin Blood Flow and Temperature during Spinal Analgesia Evaluated by Laser Doppler Flowmetry and Infrared Thermography , 1984, Acta anaesthesiologica Scandinavica.

[6]  W F Taylor,et al.  Laser-Doppler measurement of skin blood flow: comparison with plethysmography. , 1984, Journal of applied physiology: respiratory, environmental and exercise physiology.

[7]  W. Zijlstra,et al.  Intrinsic heart rate in the dog determined by pharmacologic denervation. , 1983, American Journal of Physiology.

[8]  G. Nilsson,et al.  The Effect of Spinal Analgesia on Skin Blood Flow, Evaluated by Laser Doppler Flowmetry , 1983, Acta anaesthesiologica Scandinavica.

[9]  M. Fiksen-Olsen,et al.  Role of angiotensin and vasopressin on blood pressure of ganglionic blocked dogs. , 1983, The American journal of physiology.

[10]  L. Rowell,et al.  Absence of active cutaneous vasodilation associated with congenital absence of sweat glands in humans. , 1981, The American journal of physiology.

[11]  Howard E. Evans,et al.  Miller's anatomy of the dog , 1979 .

[12]  L. Normell.  Distribution of impaired cutaneous vasomotor and sudomotor function in paraplegic man. , 1974, Scandinavian journal of clinical and laboratory investigation. Supplementum.

[13]  M. Lebeaux.  Experimental epidural anaesthesia in the dog with lignocaine and bupivacaine. , 1973, British journal of anaesthesia.

[14]  J. Bonica,et al.  Circulatory Effects of Peridural Block: II. Effects of Epinephrine , 1971, Anesthesiology.

[15]  M. Cousins,et al.  Graft, muscle, skin blood flow after epidural block in vascular surgical procedures. , 1971, Surgery, gynecology & obstetrics.

[16]  S. Shimosato,et al.  The Role of the Venous System in Cardiocirculatory Dynamics during Spinal and Epidural Anesthesia in Man , 1969, Anesthesiology.

[17]  E. Perl,et al.  Background and reflex discharge of sympathetic preganglionic neurones in the spinal cat , 1964, The Journal of physiology.

[18]  D. A. Blair,et al.  Cutaneous vasomotor nerves to the head and trunk , 1961 .

[19]  D. A. Blair,et al.  Vasomotor fibres to skin in the upper arm, calf and thigh , 1960, The Journal of physiology.

[20]  W. C. Randall,et al.  Vascular convection of heat from active muscle to overlying skin. , 1959, Journal of applied physiology.

[21]  J. Hardy,et al.  Heat Production and Heat Loss in the Dog at 8–36°C Environmental Temperature , 1958 .

[22]  O G EDHOLM,et al.  Vasomotor control of the cutaneous blood vessels in the human forearm , 1957, The Journal of physiology.

[23]  W. C. Randall,et al.  Functional Analysis of the Vasomotor Innervation of the Dog's Hind Footpad , 1953, Circulation research.

[24]  C. R. Spealman.  Effect of ambient air temperature and of hand temperature on blood flow in hands. , 1945, The American journal of physiology.

[25]  E. A. Stead,et al.  BLOOD FLOW IN THE HAND AND FOREARM AFTER PARAVERTEBRAL BLOCK OF THE SYMPATHETIC GANGLIA. EVIDENCE AGAINST SYMPATHETIC VASODILATOR NERVES IN THE EXTREMITIES OF MAN. , 1942, The Journal of clinical investigation.