An electrochemiluminescence based assay for quantitative detection of endogenous and exogenously applied MeCP2 protein variants

[1]  S. Bastianini,et al.  CDKL5 protein substitution therapy rescues neurological phenotypes of a mouse model of CDKL5 disorder , 2018, Human molecular genetics.

[2]  M. Justice,et al.  Rett syndrome: a neurological disorder with metabolic components , 2018, Open Biology.

[3]  Lan Xiao,et al.  MeCP2 Deficiency in Neuroglia: New Progress in the Pathogenesis of Rett Syndrome , 2017, Front. Mol. Neurosci..

[4]  A. Bird,et al.  MeCP2 mutations: progress towards understanding and treating Rett syndrome , 2017, Genome Medicine.

[5]  W. Kaufmann,et al.  Neurobiologically-based treatments in Rett syndrome: opportunities and challenges , 2016, Expert opinion on orphan drugs.

[6]  A. Bird,et al.  Exclusive expression of MeCP2 in the nervous system distinguishes between brain and peripheral Rett syndrome-like phenotypes , 2016, Human molecular genetics.

[7]  A. Bird,et al.  Rett Syndrome: Crossing the Threshold to Clinical Translation , 2016, Trends in Neurosciences.

[8]  S. Clark,et al.  Methyl-CpG-binding domain proteins: readers of the epigenome. , 2015, Epigenomics.

[9]  A. Bird,et al.  Rett syndrome: a complex disorder with simple roots , 2015, Nature Reviews Genetics.

[10]  C. Förster,et al.  The pivotal role of astrocytes in an in vitro stroke model of the blood-brain barrier , 2014, Front. Cell. Neurosci..

[11]  S. Cobb,et al.  MeCP2 and Rett syndrome: reversibility and potential avenues for therapy. , 2011, The Biochemical journal.

[12]  H. Esch MECP2 Duplication Syndrome. , 2011 .

[13]  H. Van Esch MECP2 Duplication Syndrome , 2011, Molecular Syndromology.

[14]  W. Kaufmann,et al.  Rett syndrome: Revised diagnostic criteria and nomenclature , 2010, Annals of neurology.

[15]  K. Riabowol,et al.  REAP: A two minute cell fractionation method , 2010, BMC Research Notes.

[16]  Stephen T. C. Wong,et al.  MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription , 2008, Science.

[17]  L. Villard MECP2 mutations in males , 2007, Journal of Medical Genetics.

[18]  A. Bird,et al.  Reversal of Neurological Defects in a Mouse Model of Rett Syndrome , 2007, Science.

[19]  C. Förster,et al.  Differential susceptibility of cerebral and cerebellar murine brain microvascular endothelial cells to loss of barrier properties in response to inflammatory stimuli , 2006, Journal of Neuroimmunology.

[20]  A. Bird,et al.  MeCP2 Behaves as an Elongated Monomer That Does Not Stably Associate with the Sin3a Chromatin Remodeling Complex* , 2004, Journal of Biological Chemistry.

[21]  H. Zoghbi,et al.  Mild overexpression of MeCP2 causes a progressive neurological disorder in mice. , 2004, Human molecular genetics.

[22]  R. Jaenisch,et al.  Expression of MeCP2 in postmitotic neurons rescues Rett syndrome in mice. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[23]  A. Bird,et al.  The major form of MeCP2 has a novel N-terminus generated by alternative splicing. , 2004, Nucleic acids research.

[24]  Haibin Xia,et al.  The HIV Tat protein transduction domain improves the biodistribution of β-glucuronidase expressed from recombinant viral vectors , 2001, Nature Biotechnology.

[25]  P. Huppke,et al.  MECP2 mutations in sporadic cases of Rett syndrome are almost exclusively of paternal origin. , 2001, American journal of human genetics.

[26]  S. Schwarze,et al.  In vivo protein transduction: delivery of a biologically active protein into the mouse. , 1999, Science.

[27]  Natalie A. Lissy,et al.  Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration , 1998, Nature Medicine.

[28]  S. Mboup,et al.  Minerva Access is the Institutional Repository of The University of Melbourne , 2021 .

[29]  J. Christodoulou,et al.  MeCP2 deficiency is associated with reduced levels of tubulin acetylation and can be restored using HDAC6 inhibitors , 2014, Journal of Molecular Medicine.

[30]  A. Bird,et al.  A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome , 2001, Nature Genetics.