Mechano-modulatory synthetic niches for liver organoid derivation
暂无分享,去创建一个
K. Schoonjans | M. Lutolf | M. Heim | G. Sorrentino | S. Rezakhani | Ece Yildiz | Sandro Nuciforo | S. Nuciforo
[1] Junjie Zhu,et al. Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture , 2018, Cell.
[2] C. Rice,et al. Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids , 2018, Cell.
[3] G. Rogler,et al. Growth of Epithelial Organoids in a Defined Hydrogel , 2018, Advanced materials.
[4] Markus H. Heim,et al. Organoid Models of Human Liver Cancers Derived from Tumor Needle Biopsies , 2018, Cell reports.
[5] T. Sulchek,et al. Periostin promotes liver fibrogenesis by activating lysyl oxidase in hepatic stellate cells , 2018, The Journal of Biological Chemistry.
[6] G. Gores,et al. YAP Tyrosine Phosphorylation and Nuclear Localization in Cholangiocarcinoma Cells Are Regulated by LCK and Independent of LATS Activity , 2018, Molecular Cancer Research.
[7] H. Baharvand,et al. Three‐dimensional liver‐derived extracellular matrix hydrogel promotes liver organoids function , 2018, Journal of cellular biochemistry.
[8] V. Shah,et al. Mechanosensing and fibrosis , 2018, The Journal of clinical investigation.
[9] C. Henke,et al. Extracellular matrix as a driver of progressive fibrosis. , 2018, The Journal of clinical investigation.
[10] G. Gores,et al. Platelet‐derived growth factor regulates YAP transcriptional activity via Src family kinase dependent tyrosine phosphorylation , 2018, Journal of cellular biochemistry.
[11] Hui Zhao,et al. Mechanotransduction-modulated fibrotic microniches reveal the contribution of angiogenesis in liver fibrosis. , 2017, Nature materials.
[12] H. Parving,et al. Circulating matrix metalloproteinases are associated with arterial stiffness in patients with type 1 diabetes: pooled analysis of three cohort studies , 2017, Cardiovascular Diabetology.
[13] Matthias P Lutolf,et al. Synthesis and characterization of well-defined hydrogel matrices and their application to intestinal stem cell and organoid culture , 2017, Nature Protocols.
[14] Sha Huang,et al. Synthetic Hydrogels for Human Intestinal Organoid Generation and Colonic Wound Repair , 2017, Nature Cell Biology.
[15] M. Battaglia,et al. Regulatory T-cells from pancreatic lymphnodes of patients with type-1 diabetes express increased levels of microRNA miR-125a-5p that limits CCR2 expression , 2017, Scientific Reports.
[16] H. Clevers,et al. Converging biofabrication and organoid technologies: the next frontier in hepatic and intestinal tissue engineering? , 2017, Biofabrication.
[17] S. Bicciato,et al. Glucocorticoid receptor signalling activates YAP in breast cancer , 2017, Nature Communications.
[18] H. Clevers,et al. Designer matrices for intestinal stem cell and organoid culture , 2016, Nature.
[19] S. Arron,et al. αE-catenin inhibits a Src–YAP1 oncogenic module that couples tyrosine kinases and the effector of Hippo signaling pathway , 2016, Genes & development.
[20] Nam‐Gyun Kim,et al. Adhesion to fibronectin regulates Hippo signaling via the FAK–Src–PI3K pathway , 2015, The Journal of cell biology.
[21] R. Nusse,et al. Self-renewing diploid Axin2+ cells fuel homeostatic renewal of the liver , 2015, Nature.
[22] John T. Chang,et al. A gp130–Src–YAP module links inflammation to epithelial regeneration , 2015, Nature.
[23] Hans Clevers,et al. Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver , 2015, Cell.
[24] Jay D. Humphrey,et al. Mechanotransduction and extracellular matrix homeostasis , 2014, Nature Reviews Molecular Cell Biology.
[25] N. Nieto,et al. Extracellular matrix and liver disease. , 2014, Antioxidants & redox signaling.
[26] M. Longaker,et al. Mechanotransduction and fibrosis. , 2014, Journal of biomechanics.
[27] J. Xie,et al. Substrate stiffness-regulated matrix metalloproteinase output in myocardial cells and cardiac fibroblasts: implications for myocardial fibrosis. , 2014, Acta biomaterialia.
[28] I. Schneider,et al. Cellular contractility and extracellular matrix stiffness regulate matrix metalloproteinase activity in pancreatic cancer cells , 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[29] A. Rosato,et al. Metabolic control of YAP and TAZ by the mevalonate pathway , 2014, Nature Cell Biology.
[30] Takanori Takebe,et al. Generation of a vascularized and functional human liver from an iPSC-derived organ bud transplant , 2014, Nature Protocols.
[31] Robert P. Jenkins,et al. Mechano-transduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer associated fibroblasts , 2013, Nature Cell Biology.
[32] H. Clevers,et al. In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration , 2013, Nature.
[33] Stefano Piccolo,et al. Transduction of mechanical and cytoskeletal cues by YAP and TAZ , 2012, Nature Reviews Molecular Cell Biology.
[34] R. Hynes,et al. The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain , 2012, Proceedings of the National Academy of Sciences.
[35] Jun O. Liu,et al. Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP. , 2012, Genes & development.
[36] S. Thorgeirsson,et al. Hepatocyte growth factor/c‐met signaling is required for stem‐cell–mediated liver regeneration in mice , 2012, Hepatology.
[37] L. Sandrin,et al. Reversal of hepatic fibrosis: pathophysiological basis of antifibrotic therapies , 2011, Hepatic medicine : evidence and research.
[38] Nicola Elvassore,et al. Role of YAP/TAZ in mechanotransduction , 2011, Nature.
[39] C. Tamm,et al. Regulation of mouse embryonic stem cell self-renewal by a Yes–YAP–TEAD2 signaling pathway downstream of LIF , 2011, Journal of Cell Science.
[40] P. Bedossa,et al. Diagnostic accuracy of FibroScan and comparison to liver fibrosis biomarkers in chronic viral hepatitis: a multicenter prospective study (the FIBROSTIC study). , 2010, Journal of hepatology.
[41] Christopher Logothetis,et al. Dasatinib: a potent SRC inhibitor in clinical development for the treatment of solid tumors. , 2010, Cancer treatment reviews.
[42] E. Messersmith,et al. Organ Donation and Utilization in the United States, 1999–2008 , 2010, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
[43] George K. Michalopoulos. Liver regeneration , 2007, Journal of cellular physiology.
[44] S. Bellusci,et al. Fibroblast growth factor 10 is critical for liver growth during embryogenesis and controls hepatoblast survival via β‐catenin activation , 2007 .
[45] Matthias P Lutolf,et al. Biomolecular hydrogels formed and degraded via site-specific enzymatic reactions. , 2007, Biomacromolecules.
[46] Armando Manduca,et al. Quantitative assessment of hepatic fibrosis in an animal model with magnetic resonance elastography , 2007, Magnetic resonance in medicine.
[47] W. Marks,et al. Organ donation and utilization in the United States, 2004 , 2005, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
[48] L. Hansen,et al. Dexamethasone effects on rat hepatocyte spheroid formation and function. , 2005, Tissue engineering.
[49] J. Sellers,et al. Mechanism of Blebbistatin Inhibition of Myosin II* , 2004, Journal of Biological Chemistry.
[50] Donald E Ingber,et al. Mechanobiology and diseases of mechanotransduction , 2003, Annals of medicine.
[51] Roger Williams,et al. Acute liver failure: redefining the syndromes , 1993, The Lancet.
[52] S. Thorgeirsson,et al. A precursor-product relationship exists between oval cells and hepatocytes in rat liver. , 1987, Carcinogenesis.
[53] Lauren E. Stopfer,et al. CALL FOR PAPERS Translational Research in Acute Lung Injury and Pulmonary Fibrosis Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis , 2015 .