Slowing down of adult body mass index trend increases in England: a latent class analysis of cross-sectional surveys (1992–2010)

Background:The prevalence of excess body weight, commonly measured as body mass index (BMI)⩾25 kg m−2, has increased substantially in many populations worldwide over the past three decades, but the rate of increase has slowed down in some western populations.Objective:We address the hypothesis that the slowing down of BMI trend increases in England reflects a majority sub-population resistant to further BMI elevation.Design:Pseudo-panel data derived from annual cross-sectional surveys, the Health Surveys for England (1992–2010). Trends in median BMI values were explored using regression models with splines, and gender-specific mixture model (latent class analysis) were fit to take an account of increasing BMI distribution variance with time and identify hidden subgroups within the population.Subjects:BMI was available for 164 155 adults (men: 76 382; women: 87 773).Results:Until 2001, the age-adjusted yearly increases in median BMI were 0.140 and 0.139 kg m−2 for men and women, respectively, decreasing thereafter to 0.073 and 0.055 kg m−2 (differences between time periods, both P-values<0.0001). The mixture model identified two components—a normal BMI and a high BMI sub-population—the proportions for the latter were 23.5% in men and 33.7% in women. The remaining normal BMI populations were ‘resistant’ with minimal increases in mean BMI values over time. By age, mean BMI values in the normal BMI sub-population increased greatest between 20 and 34 years for men; for women, the increases were similar throughout age groups (slope differences, P<0.0001).Conclusion:In England, recent slowing down of adult BMI trend increases can be explained by two sub-populations—a high BMI sub-population getting ‘fatter’ and a majority ‘resistant’ normal BMI sub-population. These findings support a targeted, rather than a population-wide, policy to tackle the determinants of obesity.

[1]  E. Stamatakis,et al.  Temporal trends in adults’ sports participation patterns in England between 1997 and 2006: the Health Survey for England , 2008, British Journal of Sports Medicine.

[2]  S. Jebb,et al.  Executive Summary: FORESIGHT ‘Tackling Obesities: Future Choices’ project , 2007, Obesity reviews : an official journal of the International Association for the Study of Obesity.

[3]  M. Zwahlen,et al.  Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies , 2008, The Lancet.

[4]  Katherine M Flegal,et al.  Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010. , 2012, JAMA.

[5]  Alan D. Lopez,et al.  A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 , 2012, The Lancet.

[6]  S. Jebb,et al.  Foresight. Tackling obesities: future choices. Project report. , 2007 .

[7]  A. Plasència,et al.  Obesity and overweight trends in Catalonia, Spain (1992–2003): gender and socio-economic determinants , 2007, Public Health Nutrition.

[8]  Mark Woodward,et al.  Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies. , 2011, Lancet.

[9]  Jennifer S. Mindell,et al.  Health Survey for England 2008 , 2009 .

[10]  H. Stenlund,et al.  The obesity epidemic slows among the middle-aged population in Sweden while the socioeconomic gap widens , 2010, Global health action.

[11]  D. Faeh,et al.  Excess weight in the canton of Zurich, 1992-2009: harbinger of a trend reversal in Switzerland? , 2010, Swiss medical weekly.

[12]  J. Mindell,et al.  Trends in obesity among adults in England from 1993 to 2004 by age and social class and projections of prevalence to 2012 , 2008, Journal of Epidemiology & Community Health.

[13]  B. Gersh National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants , 2012 .

[14]  J. Cerhan,et al.  Association of Gain and Loss of Weight before and after Menopause with Risk of Postmenopausal Breast Cancer in the Iowa Women's Health Study , 2005, Cancer Epidemiology Biomarkers & Prevention.

[15]  Sander Greenland,et al.  Case–Control Studies , 2008 .

[16]  J. Mackenbach,et al.  Time trends and forecasts of body mass index from repeated cross‐sectional data: a different approach , 2013, Statistics in medicine.

[17]  K. Adams,et al.  Body mass index at different adult ages, weight change, and colorectal cancer risk in the National Institutes of Health-AARP Cohort. , 2012, American journal of epidemiology.

[18]  D. Howel Trends in the prevalence of obesity and overweight in English adults by age and birth cohort, 1991–2006 , 2010, Public Health Nutrition.

[19]  K. Flegal,et al.  Prevalence and trends in obesity among US adults, 1999-2008. , 2010, JAMA.

[20]  E. Brunner,et al.  Deprivation and the development of obesity a multilevel, longitudinal study in England. , 2010, American journal of preventive medicine.

[21]  Geoffrey J. McLachlan,et al.  Finite Mixture Models , 2019, Annual Review of Statistics and Its Application.

[22]  J. Mindell,et al.  Health Survey for England 2006. Cardiovascular disease and risk factors in adults , 2008 .

[23]  Beyond energy balance: there is more to obesity than kilocalories. , 2005, Journal of the American Dietetic Association.

[24]  R. Kuczmarski,et al.  Effects of age on validity of self-reported height, weight, and body mass index: findings from the Third National Health and Nutrition Examination Survey, 1988-1994. , 2001, Journal of the American Dietetic Association.

[25]  Jennifer L Baker,et al.  The levelling off of the obesity epidemic since the year 1999 – a review of evidence and perspectives , 2010, Obesity reviews : an official journal of the International Association for the Study of Obesity.

[26]  I. Soerjomataram,et al.  Interpreting the epidemiological evidence linking obesity and cancer: A framework for population-attributable risk estimations in Europe. , 2010, European journal of cancer.

[27]  James J Schlesselman Case-Control Studies: Design, Conduct, Analysis , 1982 .

[28]  W. Willett,et al.  Prospective weight change and colon cancer risk in male US health professionals , 2008, International journal of cancer.

[29]  Alan D. Lopez,et al.  A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 , 2012, The Lancet.

[30]  Marno Verbeek,et al.  Pseudo Panels and Repeated Cross-Sections , 2007 .

[31]  D. Albanes,et al.  Adiposity, adult weight change, and postmenopausal breast cancer risk. , 2006, Archives of internal medicine.

[32]  D. Jacobs,et al.  Comparison of body mass index, waist circumference, and waist/hip ratio in predicting incident diabetes: a meta-analysis. , 2007, Epidemiologic reviews.

[33]  S. Gortmaker,et al.  Health and economic burden of the projected obesity trends in the USA and the UK , 2011, The Lancet.