Nitrative stress in refractory asthma.

[1]  P. Barnes.  Against the Dutch hypothesis: asthma and chronic obstructive pulmonary disease are distinct diseases. , 2006, American journal of respiratory and critical care medicine.

[2]  S. Rennard,et al.  Reactive nitrogen species augment fibroblast-mediated collagen gel contraction, mediator production, and chemotaxis. , 2006, American journal of respiratory cell and molecular biology.

[3]  I. Adcock,et al.  Epigenetics and airways disease , 2006, Respiratory research.

[4]  A. Zwinderman,et al.  "Refractory" eosinophilic airway inflammation in severe asthma: effect of parenteral corticosteroids. , 2004, American journal of respiratory and critical care medicine.

[5]  I. Adcock,et al.  Oxidative stress reduces histone deacetylase 2 activity and enhances IL-8 gene expression: role of tyrosine nitration. , 2004, Biochemical and biophysical research communications.

[6]  K. Shirato,et al.  Xanthine oxidase inhibition reduces reactive nitrogen species production in COPD airways , 2003, European Respiratory Journal.

[7]  D. Postma,et al.  The ENFUMOSA cross-sectional European multicentre study of the clinical phenotype of chronic severe asthma , 2003, European Respiratory Journal.

[8]  W. MacNee,et al.  Oxidative stress and lung inflammation in airways disease. , 2001, European journal of pharmacology.

[9]  K. Shirato,et al.  Allergic airway hyperresponsiveness and eosinophil infiltration is reduced by a selective iNOS inhibitor, 1400W, in mice. , 2000, Pulmonary pharmacology & therapeutics.

[10]  H. E. Marshall,et al.  Nitrosation and oxidation in the regulation of gene expression , 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[11]  I. Adcock,et al.  Glucocorticoid Receptor Recruitment of Histone Deacetylase 2 Inhibits Interleukin-1β-Induced Histone H4 Acetylation on Lysines 8 and 12 , 2000, Molecular and Cellular Biology.

[12]  A. Choi,et al.  Lung redox homeostasis: emerging concepts. , 2000, American journal of physiology. Lung cellular and molecular physiology.

[13]  K. Shirato,et al.  Increase in reactive nitrogen species production in chronic obstructive pulmonary disease airways. , 2000, American journal of respiratory and critical care medicine.

[14]  P. O'Byrne,et al.  Induced sputum cell counts in healthy adults. , 2000, American journal of respiratory and critical care medicine.

[15]  S. Spector,et al.  Proceedings of the ATS workshop on refractory asthma: current understanding, recommendations, and unanswered questions. American Thoracic Society. , 2000, American journal of respiratory and critical care medicine.

[16]  R. Homer,et al.  Airway remodeling in asthma. , 1999, The Journal of clinical investigation.

[17]  A. James,et al.  Nitrotyrosine formation in the airways and lung parenchyma of patients with asthma. , 1999, The Journal of allergy and clinical immunology.

[18]  W. Busse,et al.  Airway remodeling and repair. , 1999, American journal of respiratory and critical care medicine.

[19]  H. Maeda,et al.  Role of peroxynitrite in airway microvascular hyperpermeability during late allergic phase in guinea pigs. , 1999, American journal of respiratory and critical care medicine.

[20]  A. Flahault,et al.  Reactive oxygen and nitrogen intermediates increase transforming growth factor-beta1 release from human epithelial alveolar cells through two different mechanisms. , 1999, American journal of respiratory cell and molecular biology.

[21]  P. Montuschi,et al.  Increased 8-isoprostane, a marker of oxidative stress, in exhaled condensate of asthma patients. , 1999, American journal of respiratory and critical care medicine.

[22]  V. Plaza,et al.  Costs of asthma according to the degree of severity. , 1998, The European respiratory journal.

[23]  J. Filep,et al.  Peroxynitrite mediates IL-8 gene expression and production in lipopolysaccharide-stimulated human whole blood. , 1998, Journal of immunology.

[24]  P. Barnes,et al.  Increased formation of the potent oxidant peroxynitrite in the airways of asthmatic patients is associated with induction of nitric oxide synthase: effect of inhaled glucocorticoid , 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[25]  Barry Halliwell,et al.  Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils , 1998, Nature.

[26]  J. M. Cousin,et al.  Opposing effects of glucocorticoids on the rate of apoptosis in neutrophilic and eosinophilic granulocytes. , 1996, Journal of immunology.

[27]  I. van Ark,et al.  Peroxynitrite induces airway hyperresponsiveness in guinea pigs in vitro and in vivo. , 1996, American journal of respiratory and critical care medicine.

[28]  J. Stamler,et al.  Nitric oxide synthase in human and rat lung: immunocytochemical and histochemical localization. , 1993, American journal of respiratory cell and molecular biology.

[29]  S. Godfrey,et al.  Total population survey of the frequency and severity of asthma in 17 year old boys in an urban area in Israel. , 1993, Thorax.

[30]  S. Moncada,et al.  Glucocorticoids inhibit the expression of an inducible, but not the constitutive, nitric oxide synthase in vascular endothelial cells. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[31]  R. Djukanović,et al.  Mucosal inflammation in asthma. , 1990, The American review of respiratory disease.

[32]  B. Freeman,et al.  Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. , 1990, Proceedings of the National Academy of Sciences of the United States of America.