Personalized TMS helmets for quick and reliable TMS administration outside of a laboratory setting

Transcranial magnetic stimulation (TMS) administration currently necessitates trained operators and equipment to hold the coil in place over specific brain targets [1], limiting its application in ambulatory, hospital or home settings. We have developed custom, individually-tailored TMS helmets that allow one to administer TMS in diverse settings where trained TMS operators are unavailable or the experiment or treatment involves movement such as ambulatory, extreme environments, or potentially at home. Here we overview how we constructed helmets that fix a TMS coil into position over a participant’s motor hotspot (Fig. 1a and b) and describe its stepwise fabrication with video accompaniment (Supplemental Video). We also present withinand between-visit reliability resting motor thresholds (rMT) while wearing the helmets.