UV-B photoreceptor-mediated signalling in plants.

Ultraviolet-B radiation (UV-B) is a key environmental signal that is specifically perceived by plants to promote UV acclimation and survival in sunlight. Whereas the plant photoreceptors for visible light are rather well characterised, the UV-B photoreceptor UVR8 was only recently described at the molecular level. Here, we review the current understanding of the UVR8 photoreceptor-mediated pathway in the context of UV-B perception mechanism, early signalling components and physiological responses. We further outline the commonalities in UV-B and visible light signalling as well as highlight differences between these pathways.

[1]  P. Schulze-Lefert,et al.  Repression of Sucrose/Ultraviolet B Light-Induced Flavonoid Accumulation in Microbe-Associated Molecular Pattern-Triggered Immunity in Arabidopsis1[W] , 2011, Plant Physiology.

[2]  E. Schäfer,et al.  FHY1 and FHL act together to mediate nuclear accumulation of the phytochrome A photoreceptor. , 2006, Plant & cell physiology.

[3]  Gareth I Jenkins,et al.  UVR8 in Arabidopsis thaliana regulates multiple aspects of cellular differentiation during leaf development in response to ultraviolet B radiation. , 2009, The New phytologist.

[4]  Gareth I. Jenkins,et al.  UV‐B Action Spectrum for UVR8‐Mediated HY5 Transcript Accumulation in Arabidopsis , 2009, Photochemistry and photobiology.

[5]  L. Klotz,et al.  Lightening up the UV response by identification of the arylhydrocarbon receptor as a cytoplasmatic target for ultraviolet B radiation , 2007, Proceedings of the National Academy of Sciences.

[6]  F. W. Smith,et al.  Purification of the yeast PHR1 photolyase from an Escherichia coli overproducing strain and characterization of the intrinsic chromophores of the enzyme. , 1987, The Journal of biological chemistry.

[7]  V. Rubio,et al.  The COP1-SPA1 interaction defines a critical step in phytochrome A-mediated regulation of HY5 activity. , 2003, Genes & development.

[8]  C. Ballaré,et al.  Chromosomal loci important for cotyledon opening under UV-B in Arabidopsis thaliana , 2010, BMC Plant Biology.

[9]  S. Flint,et al.  Effects of solar ultraviolet radiation on terrestrial ecosystems. Patterns, mechanisms, and interactions with climate change , 2011, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

[10]  Y. Guisez,et al.  Plant stress and human health: Do human consumers benefit from UV-B acclimated crops? , 2008 .

[11]  Min Wu,et al.  Computational Evidence for the Role of Arabidopsis thaliana UVR8 as UV-B Photoreceptor and Identification of Its Chromophore Amino Acids , 2011, J. Chem. Inf. Model..

[12]  E. Logemann,et al.  Crosstalk among stress responses in plants: Pathogen defense overrides UV protection through an inversely regulated ACE/ACE type of light-responsive gene promoter unit , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[13]  Edward J Oakeley,et al.  Interaction of COP1 and UVR8 regulates UV‐B‐induced photomorphogenesis and stress acclimation in Arabidopsis , 2009, The EMBO journal.

[14]  Pawel Herzyk,et al.  A UV-B-specific signaling component orchestrates plant UV protection. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[15]  X. Deng,et al.  Two interacting bZIP proteins are direct targets of COP1-mediated control of light-dependent gene expression in Arabidopsis. , 2002, Genes & development.

[16]  H. Hellmann,et al.  root uv-b sensitive mutants are suppressed by specific mutations in ASPARTATE AMINOTRANSFERASE2 and by exogenous vitamin B6. , 2011, Molecular plant.

[17]  C. Cloix,et al.  Interaction of the Arabidopsis UV-B-specific signaling component UVR8 with chromatin. , 2008, Molecular plant.

[18]  Gareth I Jenkins,et al.  Signal transduction in responses to UV-B radiation. , 2009, Annual review of plant biology.

[19]  A. Cashmore,et al.  The Signaling Mechanism of Arabidopsis CRY1 Involves Direct Interaction with COP1 Article, publication date, and citation information can be found at www.plantcell.org/cgi/doi/10.1105/tpc.010367. , 2001, The Plant Cell Online.

[20]  S. Flint,et al.  UV-B Radiation, Photomorphogenesis and Plant-Plant Interactions , 2005 .

[21]  X. Deng,et al.  HY5 stability and activity in Arabidopsis is regulated by phosphorylation in its COP1 binding domain , 2000, The EMBO journal.

[22]  K. Cronin,et al.  UV- and gamma-radiation sensitive mutants of Arabidopsis thaliana. , 1997, Genetics.

[23]  Haiyang Wang,et al.  Biochemical Characterization of Arabidopsis Complexes Containing CONSTITUTIVELY PHOTOMORPHOGENIC1 and SUPPRESSOR OF PHYA Proteins in Light Control of Plant Development[W] , 2008, The Plant Cell Online.

[24]  F. Nagy,et al.  Signalling and gene regulation in response to ultraviolet light. , 2005, Current opinion in plant biology.

[25]  B. Liu,et al.  Arabidopsis cryptochrome 1 interacts with SPA1 to suppress COP1 activity in response to blue light. , 2011, Genes & development.

[26]  Gareth I Jenkins,et al.  UV-B Signaling Pathways with Different Fluence-Rate Response Profiles Are Distinguished in Mature Arabidopsis Leaf Tissue by Requirement for UVR8, HY5, and HYH1[W][OA] , 2007, Plant Physiology.

[27]  C. Ballaré,et al.  Functional significance and induction by solar radiation of ultraviolet-absorbing sunscreens in field-grown soybean crops. , 2000, Plant physiology.

[28]  D. Kliebenstein,et al.  Arabidopsis UVR8 Regulates Ultraviolet-B Signal Transduction and Tolerance and Contains Sequence Similarity to Human Regulator of Chromatin Condensation 1 , 2002, Plant Physiology.

[29]  S. van Nocker,et al.  The WD-repeat protein superfamily in Arabidopsis: conservation and divergence in structure and function , 2003, BMC Genomics.

[30]  S. Laubinger,et al.  The SPA Quartet: A Family of WD-Repeat Proteins with a Central Role in Suppression of Photomorphogenesis in Arabidopsis , 2004, The Plant Cell Online.

[31]  R. Ulm,et al.  Arabidopsis MAP kinase phosphatase 1 and its target MAP kinases 3 and 6 antagonistically determine UV-B stress tolerance, independent of the UVR8 photoreceptor pathway. , 2011, The Plant journal : for cell and molecular biology.

[32]  R. Stracke,et al.  The Arabidopsis bZIP transcription factor HY5 regulates expression of the PFG1/MYB12 gene in response to light and ultraviolet-B radiation. , 2010, Plant, cell & environment.

[33]  K. Feldmann,et al.  EFO1 and EFO2, encoding putative WD-domain proteins, have overlapping and distinct roles in the regulation of vegetative development and flowering of Arabidopsis. , 2011, Journal of experimental botany.

[34]  Chentao Lin,et al.  The action mechanisms of plant cryptochromes. , 2011, Trends in plant science.

[35]  S. Laubinger,et al.  Functional and expression analysis of Arabidopsis SPA genes during seedling photomorphogenesis and adult growth. , 2006, The Plant journal : for cell and molecular biology.

[36]  N. Paul,et al.  Ecological roles of solar UV radiation: towards an integrated approach , 2003 .

[37]  E. Huq,et al.  A light-switchable gene promoter system , 2002, Nature Biotechnology.

[38]  Eberhard Schäfer,et al.  Perception of UV-B by the Arabidopsis UVR8 Protein , 2011, Science.

[39]  Edward J Oakeley,et al.  CONSTITUTIVELY PHOTOMORPHOGENIC1 Is Required for the UV-B Response in Arabidopsis[W] , 2006, The Plant Cell Online.

[40]  Gareth I Jenkins,et al.  UV-B Promotes Rapid Nuclear Translocation of the Arabidopsis UV-B–Specific Signaling Component UVR8 and Activates Its Function in the Nucleus , 2007, The Plant Cell Online.

[41]  K. Hellingwerf,et al.  Is the photoactive yellow protein a UV-B/blue light photoreceptor? , 2011, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

[42]  Haiyang Wang,et al.  Direct Interaction of Arabidopsis Cryptochromes with COP1 in Light Control Development , 2001, Science.

[43]  E. Schäfer,et al.  Functional interaction of the circadian clock and UV RESISTANCE LOCUS 8-controlled UV-B signaling pathways in Arabidopsis thaliana. , 2011, The Plant journal : for cell and molecular biology.

[44]  Xing Wang Deng,et al.  COP1 - from plant photomorphogenesis to mammalian tumorigenesis. , 2005, Trends in cell biology.

[45]  E. Oakeley,et al.  Genome-wide analysis of gene expression reveals function of the bZIP transcription factor HY5 in the UV-B response of Arabidopsis. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[46]  W. Terzaghi,et al.  Characterization of Arabidopsis and Rice DWD Proteins and Their Roles as Substrate Receptors for CUL4-RING E3 Ubiquitin Ligases[W] , 2008, The Plant Cell Online.

[47]  C. Ballaré,et al.  Jasmonate-Dependent and -Independent Pathways Mediate Specific Effects of Solar Ultraviolet B Radiation on Leaf Phenolics and Antiherbivore Defense1[W][OA] , 2009, Plant Physiology.

[48]  Xing Wang Deng,et al.  Targeted destabilization of HY5 during light-regulated development of Arabidopsis , 2000, Nature.

[49]  L. Björn,et al.  UV-B as an environmental factor in plant life: stress and regulation. , 1997, Trends in ecology & evolution.

[50]  A. Murphy,et al.  Arabidopsis ROOT UVB SENSITIVE2/WEAK AUXIN RESPONSE1 Is Required for Polar Auxin Transport[C][W] , 2010, Plant Cell.

[51]  Chentao Lin,et al.  Photoexcited CRY2 Interacts with CIB1 to Regulate Transcription and Floral Initiation in Arabidopsis , 2008, Science.

[52]  A. Sancar,et al.  The third chromophore of DNA photolyase: Trp-277 of Escherichia coli DNA photolyase repairs thymine dimers by direct electron transfer. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[53]  C. Fankhauser,et al.  The Degradation of HFR1, a Putative bHLH Class Transcription Factor Involved in Light Signaling, Is Regulated by Phosphorylation and Requires COP1 , 2004, Current Biology.

[54]  C. Fankhauser,et al.  Light-regulated plant growth and development. , 2010, Current topics in developmental biology.

[55]  R. McKenzie,et al.  Changes in biologically active ultraviolet radiation reaching the Earth's surface. , 1998, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

[56]  Promotion of photomorphogenesis by COP1 , 2004, Plant Molecular Biology.

[57]  Xuanming Liu,et al.  Blue Light-Dependent Interaction of CRY2 with SPA1 Regulates COP1 activity and Floral Initiation in Arabidopsis , 2011, Current Biology.

[58]  R. Last,et al.  Arabidopsis Flavonoid Mutants Are Hypersensitive to UV-B Irradiation. , 1993, The Plant cell.

[59]  R. McKenzie,et al.  Changes in biologically active ultraviolet radiation reaching the Earth’s surface , 2003, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

[60]  W. Briggs,et al.  Role of root UV-B sensing in Arabidopsis early seedling development , 2008, Proceedings of the National Academy of Sciences.

[61]  Cornelius S. Barry,et al.  Manipulation of light signal transduction as a means of modifying fruit nutritional quality in tomato. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[62]  J. J. Chen,et al.  A UV-sensitive mutant of Arabidopsis defective in the repair of pyrimidine-pyrimidinone(6-4) dimers. , 1993, Science.

[63]  M. Heijde,et al.  Negative feedback regulation of UV-B–induced photomorphogenesis and stress acclimation in Arabidopsis , 2010, Proceedings of the National Academy of Sciences.

[64]  Yan-chun Zhang,et al.  Blue-light-dependent interaction of cryptochrome 1 with SPA1 defines a dynamic signaling mechanism. , 2011, Genes & development.

[65]  L. Björn,et al.  Arabidopsis RADICAL-INDUCED CELL DEATH1 is involved in UV-B signaling , 2009, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

[66]  A. Britt Repair of DNA Damage Induced by Solar UV , 2004, Photosynthesis Research.

[67]  L. Eriksson,et al.  The role of the pyridoxine (vitamin B6) biosynthesis enzyme PDX1 in ultraviolet-B radiation responses in plants. , 2011, Plant physiology and biochemistry : PPB.

[68]  D. Scheel,et al.  Crosstalk between abiotic ultraviolet-B stress and biotic (flg22) stress signalling in Arabidopsis prevents flavonol accumulation in favor of pathogen defence compound production. , 2011, Plant, cell & environment.

[69]  D. Francis,et al.  Progress in Botany , 2011, Progress in Botany.