Non-invasive insight into the release mechanisms of a poorly soluble drug from amorphous solid dispersions by confocal Raman microscopy.

[1]  J. Nanubolu,et al.  In situ Raman mapping for identifying transient solid forms , 2015 .

[2]  František Štěpánek,et al.  Identifying the mechanisms of drug release from amorphous solid dispersions using MRI and ATR-FTIR spectroscopic imaging. , 2015, International journal of pharmaceutics.

[3]  J. Aylott,et al.  Real time Raman imaging to understand dissolution performance of amorphous solid dispersions. , 2014, Journal of controlled release : official journal of the Controlled Release Society.

[4]  F. Štěpánek,et al.  Investigation of drug-polymer interaction in solid dispersions by vapour sorption methods. , 2014, International journal of pharmaceutics.

[5]  Wei Wu,et al.  Understanding the relationship between wettability and dissolution of solid dispersion. , 2014, International journal of pharmaceutics.

[6]  N. Fotaki,et al.  Pharmaceutical characterisation and evaluation of cocrystals: Importance of in vitro dissolution conditions and type of coformer. , 2013, International journal of pharmaceutics.

[7]  Thomas Rades,et al.  Emerging trends in the stabilization of amorphous drugs. , 2013, International journal of pharmaceutics.

[8]  O. Shirai,et al.  Inhibition of crystal nucleation and growth by water-soluble polymers and its impact on the supersaturation profiles of amorphous drugs. , 2013, Journal of pharmaceutical sciences.

[9]  P. Sriamornsak,et al.  Physical Stabilizing Effect of Biopolymers on Solid Dispersions Containing Indomethacin and Polyethylene Glycol , 2012 .

[10]  S. Das,et al.  Solid Dispersions : An Approach to Enhance the Bioa vailability of Poorly Water-Soluble Drugs , 2012 .

[11]  Keith C Gordon,et al.  Raman mapping of pharmaceuticals. , 2011, International journal of pharmaceutics.

[12]  H. Santos,et al.  Comparison of mesoporous silicon and non-ordered mesoporous silica materials as drug carriers for itraconazole. , 2011, International journal of pharmaceutics.

[13]  G. Van den Mooter,et al.  Review: physical chemistry of solid dispersions , 2009 .

[14]  Patrick Augustijns,et al.  Supersaturating drug delivery systems: the answer to solubility-limited oral bioavailability? , 2009, Journal of pharmaceutical sciences.

[15]  Ulf Olsson,et al.  Nucleation and crystal growth in supersaturated solutions of a model drug. , 2008, Journal of colloid and interface science.

[16]  B. Sarmento,et al.  Solid dispersions as strategy to improve oral bioavailability of poor water soluble drugs. , 2007, Drug discovery today.

[17]  Colin W Pouton,et al.  Formulation of poorly water-soluble drugs for oral administration: physicochemical and physiological issues and the lipid formulation classification system. , 2006, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[18]  H. Gotoh,et al.  Physicochemical properties of amorphous salt of cimetidine and diflunisal system. , 2002, International journal of pharmaceutics.

[19]  D. Craig,et al.  The mechanisms of drug release from solid dispersions in water-soluble polymers. , 2002, International journal of pharmaceutics.

[20]  J Dressman,et al.  Improving drug solubility for oral delivery using solid dispersions. , 2000, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[21]  Jae-Young Jung,et al.  Enhanced solubility and dissolution rate of itraconazole by a solid dispersion technique. , 1999, International journal of pharmaceutics.

[22]  A. Serajuddin,et al.  Solid dispersion of poorly water-soluble drugs: early promises, subsequent problems, and recent breakthroughs. , 1999, Journal of pharmaceutical sciences.

[23]  Toshio Oguchi,et al.  Improved dissolution of ofloxacin via solid dispersion , 1997 .

[24]  G. N. Sheth Studies in interaction between polyvinyl pyrrolidone and stilbene fluorescent compounds II. Interaction with mixture of compounds , 1986 .

[25]  O. Corrigan,et al.  Retardation of Polymeric Carrier Dissolution by Dispersed Drugs: Factors Influencing the Dissolution of Solid Dispersions Containing Polyethlene Glycols , 1986 .

[26]  S. Riegelman,et al.  Pharmaceutical applications of solid dispersion systems. , 1971, Journal of pharmaceutical sciences.

[27]  W I Higuchi,et al.  Dissolution rates of polyphase mixtures. , 1965, Journal of pharmaceutical sciences.