Dhrs3a regulates retinoic acid biosynthesis through a feedback inhibition mechanism.

[1]  D. Yelon,et al.  Zebrafish retinoic acid receptors function as context-dependent transcriptional activators. , 2011, Developmental biology.

[2]  Ina Strate,et al.  Retinol dehydrogenase 10 is a feedback regulator of retinoic acid signalling during axis formation and patterning of the central nervous system , 2009, Development.

[3]  E. Linney,et al.  Retinoid regulation of the zebrafish cyp26a1 promoter , 2008, Developmental dynamics : an official publication of the American Association of Anatomists.

[4]  B. Persson,et al.  Medium- and short-chain dehydrogenase/reductase gene and protein families , 2008, Cellular and Molecular Life Sciences.

[5]  G. Duester,et al.  Medium- and short-chain dehydrogenase/reductase gene and protein families , 2008, Cellular and Molecular Life Sciences.

[6]  G. Callard,et al.  Characterization of housekeeping genes in zebrafish: male-female differences and effects of tissue type, developmental stage and chemical treatment , 2008, BMC Molecular Biology.

[7]  T. Schilling,et al.  How degrading: Cyp26s in hindbrain development , 2008, Developmental dynamics : an official publication of the American Association of Anatomists.

[8]  G. Duester.  Retinoic Acid Synthesis and Signaling during Early Organogenesis , 2008, Cell.

[9]  F. Guillemot,et al.  Combinatorial signalling controls Neurogenin2 expression at the onset of spinal neurogenesis. , 2008, Developmental biology.

[10]  Hiroaki Kitano,et al.  Biological robustness , 2008, Nature Reviews Genetics.

[11]  D. Yelon,et al.  Hoxb5b acts downstream of retinoic acid signaling in the forelimb field to restrict heart field potential in zebrafish. , 2008, Developmental cell.

[12]  P. Dollé,et al.  Retinoic acid in development: towards an integrated view , 2008, Nature Reviews Genetics.

[13]  D. Raible,et al.  Notch Signaling Regulates the Extent of Hair Cell Regeneration in the Zebrafish Lateral Line , 2008, The Journal of Neuroscience.

[14]  M. Maden.  Retinoic acid in the development, regeneration and maintenance of the nervous system , 2007, Nature Reviews Neuroscience.

[15]  A. McMahon,et al.  The cdx Genes and Retinoic Acid Control the Positioning and Segmentation of the Zebrafish Pronephros , 2007, PLoS genetics.

[16]  P. Dollé,et al.  Expression of the murine retinol dehydrogenase 10 (Rdh10) gene correlates with many sites of retinoid signalling during embryogenesis and organ differentiation , 2007, Developmental dynamics : an official publication of the American Association of Anatomists.

[17]  C. Tomlinson,et al.  Selective repression of retinoic acid target genes by RIP140 during induced tumor cell differentiation of pluripotent human embryonal carcinoma cells , 2007, Molecular Cancer.

[18]  R. Albalat,et al.  Analysis of the NADH‐dependent retinaldehyde reductase activity of amphioxus retinol dehydrogenase enzymes enhances our understanding of the evolution of the retinol dehydrogenase family , 2007, The FEBS journal.

[19]  A. Mushegian,et al.  RDH10 is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development. , 2007, Genes & development.

[20]  C. Brenner,et al.  p53 Activation by Knockdown Technologies , 2007, PLoS genetics.

[21]  Jeffrey J Schoenebeck,et al.  Illuminating cardiac development: Advances in imaging add new dimensions to the utility of zebrafish genetics. , 2007, Seminars in cell & developmental biology.

[22]  D. Yelon,et al.  Comparison of the expression patterns of newly identified zebrafish retinoic acid and retinoid X receptors , 2007, Developmental dynamics : an official publication of the American Association of Anatomists.

[23]  M. Ekker,et al.  Isolation and expression of zebrafish zinc-finger transcription factor gene tsh1. , 2007, Gene expression patterns : GEP.

[24]  L. Margaretha,et al.  Cyp26 enzymes generate the retinoic acid response pattern necessary for hindbrain development , 2007, Development.

[25]  P. Dollé,et al.  Retinoic acid regulates morphogenesis and patterning of posterior foregut derivatives. , 2006, Developmental biology.

[26]  M. Maden.  Retinoids and spinal cord development. , 2006, Journal of neurobiology.

[27]  V. Laudet,et al.  Conserved RARE localization in amphioxus Hox clusters and implications for Hox code evolution in the vertebrate neural crest , 2006, Developmental dynamics : an official publication of the American Association of Anatomists.

[28]  U. Dräger,et al.  Retinoids, eye development, and maturation of visual function. , 2006, Journal of neurobiology.

[29]  J. Postlethwait,et al.  Characterization of retinoid-X receptor genes rxra, rxrba, rxrbb and rxrg during zebrafish development. , 2006, Gene expression patterns : GEP.

[30]  M. Petkovich,et al.  Transcriptional co-operativity between distant retinoic acid response elements in regulation of Cyp26A1 inducibility. , 2005, The Biochemical journal.

[31]  Robert Geisler,et al.  beamter/deltaC and the role of Notch ligands in the zebrafish somite segmentation, hindbrain neurogenesis and hypochord differentiation. , 2005, Developmental biology.

[32]  C. Kimmel,et al.  Dynamic and sequential patterning of the zebrafish posterior hindbrain by retinoic acid. , 2005, Developmental biology.

[33]  M. Maden,et al.  The control of morphogen signalling: regulation of the synthesis and catabolism of retinoic acid in the developing embryo. , 2005, Developmental biology.

[34]  L. Gresh,et al.  Shifting boundaries of retinoic acid activity control hindbrain segmental gene expression , 2005, Development.

[35]  D. Lohnes,et al.  Chicken Ovalbumin Upstream Promoter-Transcription Factor Members Repress Retinoic Acid-induced Cdx1 Expression* , 2005, Journal of Biological Chemistry.

[36]  P. Scambler,et al.  Retinoic acid down‐regulates Tbx1 expression in vivo and in vitro , 2005, Developmental dynamics : an official publication of the American Association of Anatomists.

[37]  M. Hibi,et al.  Patterning of proneuronal and inter-proneuronal domains by hairy- and enhancer of split-related genes in zebrafish neuroectoderm , 2005, Development.

[38]  H. Okamoto,et al.  Retinoic acid-metabolizing enzyme Cyp26a1 is essential for determining territories of hindbrain and spinal cord in zebrafish. , 2005, Developmental biology.

[39]  Ken W. Y. Cho,et al.  Global analysis of RAR‐responsive genes in the Xenopus neurula using cDNA microarrays , 2005, Developmental dynamics : an official publication of the American Association of Anatomists.

[40]  P. Ingham,et al.  Retinoic Acid Signaling Restricts the Cardiac Progenitor Pool , 2005, Science.

[41]  C. Moens,et al.  vhnf1 integrates global RA patterning and local FGF signals to direct posterior hindbrain development in zebrafish , 2004, Development.

[42]  V. Prince,et al.  A conserved role for retinoid signaling in vertebrate pancreas development , 2004, Development Genes and Evolution.

[43]  Rafael A. Irizarry,et al.  A Model-Based Background Adjustment for Oligonucleotide Expression Arrays , 2004 .

[44]  A. Meyer,et al.  Beyond the neckless phenotype: influence of reduced retinoic acid signaling on motor neuron development in the zebrafish hindbrain. , 2004, Developmental biology.

[45]  T. Schilling,et al.  Independent roles for retinoic acid in segmentation and neuronal differentiation in the zebrafish hindbrain. , 2004, Developmental biology.

[46]  E. Linney,et al.  Feedback mechanisms regulate retinoic acid production and degradation in the zebrafish embryo , 2004, Mechanisms of Development.

[47]  M. Spinella,et al.  Negative Feedback at the Level of Nuclear Receptor Coregulation , 2003, Journal of Biological Chemistry.

[48]  T. Gojobori,et al.  Microarray analysis of embryonic retinoic acid target genes in the ascidian Ciona intestinalis , 2003, Development, growth & differentiation.

[49]  Yoav Benjamini,et al.  Identifying differentially expressed genes using false discovery rate controlling procedures , 2003, Bioinform..

[50]  P. Chambon,et al.  Retinaldehyde dehydrogenase 2 (RALDH2)- independent patterns of retinoic acid synthesis in the mouse embryo , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[51]  Ying Chen,et al.  Cloning and characterization of a novel all-trans retinol short-chain dehydrogenase/reductase from the RPE. , 2002, Investigative ophthalmology & visual science.

[52]  Stephen W. Wilson,et al.  Distinct roles for Fgf, Wnt and retinoic acid in posteriorizing the neural ectoderm. , 2002, Development.

[53]  V. Prince,et al.  Retinoic Acid Signaling Is Required for a Critical Early Step in Zebrafish Pancreatic Development , 2002, Current Biology.

[54]  Stephen W. Wilson,et al.  Retinoic acid signalling in the zebrafish embryo is necessary during pre-segmentation stages to pattern the anterior-posterior axis of the CNS and to induce a pectoral fin bud. , 2002, Development.

[55]  Scott Barolo,et al.  Three habits of highly effective signaling pathways: principles of transcriptional control by developmental cell signaling. , 2002, Genes & development.

[56]  R. Haselbeck,et al.  Novel retinoic acid generating activities in the neural tube and heart identified by conditional rescue of Raldh2 null mutant mice. , 2002, Development.

[57]  R. H. Gross,et al.  Developmentally-related candidate retinoic acid target genes regulated early during neuronal differentiation of human embryonal carcinoma , 2002, Oncogene.

[58]  I. Screpanti,et al.  retSDR1, a short-chain retinol dehydrogenase/reductase, is retinoic acid-inducible and frequently deleted in human neuroblastoma cell lines. , 2002, Cancer research.

[59]  A. Waskiewicz,et al.  Zebrafish Meis functions to stabilize Pbx proteins and regulate hindbrain patterning. , 2001, Development.

[60]  P. Ingham,et al.  The zebrafish neckless mutation reveals a requirement for raldh2 in mesodermal signals that pattern the hindbrain. , 2001, Development.

[61]  Pierre Baldi,et al.  A Bayesian framework for the analysis of microarray expression data: regularized t -test and statistical inferences of gene changes , 2001, Bioinform..

[62]  P. Chambon,et al.  The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures. , 2001, Genes & development.

[63]  F. Gonzalez,et al.  Feedback Inhibition of the Retinaldehyde Dehydrogenase GeneALDH1 by Retinoic Acid through Retinoic Acid Receptor α and CCAAT/Enhancer-binding Protein β* , 2000, The Journal of Biological Chemistry.

[64]  C. Martínez-A,et al.  Opposing RA and FGF signals control proximodistal vertebrate limb development through regulation of Meis genes. , 2000, Development.

[65]  R. Terranova,et al.  Altered retinoic acid sensitivity and temporal expression of Hox genes in polycomb-M33-deficient mice. , 2000, Developmental biology.

[66]  N. Manley,et al.  Retinoic acid-induced thymic abnormalities in the mouse are associated with altered pharyngeal morphology, thymocyte maturation defects, and altered expression of Hoxa3 and Pax1. , 1998, Teratology.

[67]  L. Lebioda,et al.  Molecular Characterization of a Novel Short-chain Dehydrogenase/Reductase That Reduces All-trans-retinal* , 1998, The Journal of Biological Chemistry.

[68]  R. Ho,et al.  Zebrafish hox genes: expression in the hindbrain region of wild-type and mutants of the segmentation gene, valentino. , 1998, Development.

[69]  R. Krumlauf,et al.  HOXD4 and regulation of the group 4 paralog genes. , 1997, Development.

[70]  C. Kimmel,et al.  Development of branchiomotor neurons in zebrafish. , 1997, Development.

[71]  R. Eckert,et al.  AGN193109 Is a Highly Effective Antagonist of Retinoid Action in Human Ectocervical Epithelial Cells (*) , 1996, The Journal of Biological Chemistry.

[72]  M. Tsai,et al.  Chicken ovalbumin upstream promoter-transcription factors and their regulation , 1996, The Journal of Steroid Biochemistry and Molecular Biology.

[73]  P. Chambon,et al.  Efficient cloning of cDNAs of retinoic acid-responsive genes in P19 embryonal carcinoma cells and characterization of a novel mouse gene, Stra1 (mouse LERK-2/Eplg2). , 1995, Developmental biology.

[74]  C. Kimmel,et al.  Stages of embryonic development of the zebrafish , 1995, Developmental dynamics : an official publication of the American Association of Anatomists.

[75]  A. Simeone,et al.  Retinoic acid induces stage-specific antero-posterior transformation of rostral central nervous system , 1995, Mechanisms of Development.

[76]  C. Pals,et al.  Cloning and expression during development of three murine members of the COUP family of nuclear orphan receptors , 1994, Mechanisms of Development.

[77]  W. K. Metcalfe,et al.  T reticular interneurons: A class of serially repeating cells in the zebrafish hindbrain , 1985, The Journal of comparative neurology.

[78]  W. K. Metcalfe,et al.  Brain neurons which project to the spinal cord in young larvae of the zebrafish , 1982, The Journal of comparative neurology.

[79]  T. Zhong,et al.  TBX1, a DiGeorge syndrome candidate gene, is inhibited by retinoic acid. , 2006, The International journal of developmental biology.

[80]  P. Chambon,et al.  Retinoic acid synthesis and hindbrain patterning in the mouse embryo. , 2000, Development.

[81]  F. Gonzalez,et al.  Feedback inhibition of the retinaldehyde dehydrogenase gene ALDH1 by retinoic acid through retinoic acid receptor alpha and CCAAT/enhancer-binding protein beta. , 2000, The Journal of biological chemistry.

[82]  C. Kimmel,et al.  Reticulospinal and vestibulospinal neurons in the young larva of a teleost fish, Brachydanio rerio. , 1982, Progress in brain research.