CHIP Protects from the Neurotoxicity of Expanded and Wild-type Ataxin-1 and Promotes Their Ubiquitination and Degradation*
暂无分享,去创建一个
Ismael Al-Ramahi | Juan Botas | Huda Y. Zoghbi | Cam Patterson | Joana Branco | H. Zoghbi | J. Botas | C. Patterson | Alma M. Pérez | María de Haro | I. Al-Ramahi | Hung-Kai Chen | Y. C. Lam | Yung C. Lam | Beatrice de Gouyon | Minghang Zhang | Maria de Haro | Minghang Zhang | Hung-Kai Chen | B. de Gouyon | Joana Branco
[1] Aaron Ciechanover,et al. The Ubiquitin Proteasome System in Neurodegenerative Diseases Sometimes the Chicken, Sometimes the Egg , 2003, Neuron.
[2] B. Bukau,et al. Protein Turnover: A CHIP Programmed for Proteolysis , 2002, Current Biology.
[3] B. Hyman,et al. The Co-chaperone Carboxyl Terminus of Hsp70-interacting Protein (CHIP) Mediates α-Synuclein Degradation Decisions between Proteasomal and Lysosomal Pathways* , 2005, Journal of Biological Chemistry.
[4] S. Gottesman,et al. Posttranslational quality control: folding, refolding, and degrading proteins. , 1999, Science.
[5] John Hardy,et al. CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation , 2004 .
[6] K. Nakayama,et al. U‐box protein carboxyl terminus of Hsc70‐interacting protein (CHIP) mediates poly‐ubiquitylation preferentially on four‐repeat Tau and is involved in neurodegeneration of tauopathy , 2004, Journal of neurochemistry.
[7] Harry T Orr,et al. Mutation of the E6-AP Ubiquitin Ligase Reduces Nuclear Inclusion Frequency While Accelerating Polyglutamine-Induced Pathology in SCA1 Mice , 1999, Neuron.
[8] V. Godfrey,et al. CHIP activates HSF1 and confers protection against apoptosis and cellular stress , 2003, The EMBO journal.
[9] H. Zoghbi,et al. Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice. , 2001, Human molecular genetics.
[10] Keiji Tanaka,et al. Co-chaperone CHIP Associates with Expanded Polyglutamine Protein and Promotes Their Degradation by Proteasomes* , 2005, Journal of Biological Chemistry.
[11] H. Zoghbi,et al. Mice Lacking Ataxin-1 Display Learning Deficits and Decreased Hippocampal Paired-Pulse Facilitation , 1998, The Journal of Neuroscience.
[12] Harry T Orr,et al. Recovery from Polyglutamine-Induced Neurodegeneration in Conditional SCA1 Transgenic Mice , 2004, The Journal of Neuroscience.
[13] P. Connell,et al. Identification of CHIP, a Novel Tetratricopeptide Repeat-Containing Protein That Interacts with Heat Shock Proteins and Negatively Regulates Chaperone Functions , 1999, Molecular and Cellular Biology.
[14] Juan Botas,et al. The AXH Domain of Ataxin-1 Mediates Neurodegeneration through Its Interaction with Gfi-1/Senseless Proteins , 2005, Cell.
[15] Effat S. Emamian,et al. Serine 776 of Ataxin-1 Is Critical for Polyglutamine-Induced Disease in SCA1 Transgenic Mice , 2003, Neuron.
[16] H. Zoghbi,et al. Interaction of Akt-Phosphorylated Ataxin-1 with 14-3-3 Mediates Neurodegeneration in Spinocerebellar Ataxia Type 1 , 2003, Cell.
[17] W. Alaynick,et al. Boat, an AXH domain protein, suppresses the cytotoxicity of mutant ataxin‐1 , 2005, The EMBO journal.
[18] D. Cyr,et al. CHIP Is a U-box-dependent E3 Ubiquitin Ligase , 2001, The Journal of Biological Chemistry.
[19] Steven P. Gygi,et al. CHIP-Hsc70 Complex Ubiquitinates Phosphorylated Tau and Enhances Cell Survival* , 2004, Journal of Biological Chemistry.
[20] Keiji Tanaka,et al. CHIP: a quality-control E3 ligase collaborating with molecular chaperones. , 2003, The international journal of biochemistry & cell biology.
[21] H. Zoghbi,et al. Glutamine repeats and neurodegeneration. , 2000, Annual review of neuroscience.
[22] H. Kampinga,et al. Overexpression of the Cochaperone CHIP Enhances Hsp70-Dependent Folding Activity in Mammalian Cells , 2003, Molecular and Cellular Biology.
[23] Hung-Ying Kao,et al. Ataxin 1, a SCA1 neurodegenerative disorder protein, is functionally linked to the silencing mediator of retinoid and thyroid hormone receptors , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[24] H. Paulson,et al. CHIP Suppresses Polyglutamine Aggregation and Toxicity In Vitro and In Vivo , 2005, The Journal of Neuroscience.
[25] H. Zoghbi,et al. Identification of genes that modify ataxin-1-induced neurodegeneration , 2000, Nature.
[26] D. Cyr,et al. Protein quality control: U-box-containing E3 ubiquitin ligases join the fold. , 2002, Trends in biochemical sciences.
[27] K. Nakayama,et al. CHIP promotes proteasomal degradation of familial ALS‐linked mutant SOD1 by ubiquitinating Hsp/Hsc70 , 2004, Journal of neurochemistry.
[28] P. Cohen,et al. Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex. , 2005, Molecular cell.
[29] L. Hendershot,et al. The Unfolding Tale of the Unfolded Protein Response , 2001, Cell.
[30] K. Nakayama,et al. Interaction of U‐box‐type ubiquitin‐protein ligases (E3s) with molecular chaperones , 2004, Genes to cells : devoted to molecular & cellular mechanisms.
[31] Huda Y. Zoghbi,et al. Diseases of Unstable Repeat Expansion: Mechanisms and Common Principles , 2005, Nature Reviews Genetics.
[32] Sung Goo Park,et al. Co-chaperone CHIP associates with mutant Cu/Zn-superoxide dismutase proteins linked to familial amyotrophic lateral sclerosis and promotes their degradation by proteasomes. , 2004, Biochemical and biophysical research communications.
[33] S. Benzer,et al. Genetic suppression of polyglutamine toxicity in Drosophila. , 2000, Science.
[34] Harry T Orr,et al. Ataxin-1 Nuclear Localization and Aggregation Role in Polyglutamine-Induced Disease in SCA1 Transgenic Mice , 1998, Cell.
[35] T. Hashikawa,et al. CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity. , 2002, Molecular cell.
[36] René Hen,et al. Reversal of Neuropathology and Motor Dysfunction in a Conditional Model of Huntington's Disease , 2000, Cell.