NORE1A directs apoptotic switch of TNF signaling through reciprocal modulation of ITCH-mediated destruction of TNFRI and BAX

[1]  R. García-Becerra,et al.  Preclinical and clinical aspects of TNF-α and its receptors TNFR1 and TNFR2 in breast cancer , 2017, Journal of Biomedical Science.

[2]  S. Sohal,et al.  Zinc transporters and insulin resistance: therapeutic implications for type 2 diabetes and metabolic disease , 2017, Journal of Biomedical Science.

[3]  S. Fitter,et al.  mTORC1 Plays an Important Role in Skeletal Development by Controlling Preosteoblast Differentiation , 2017, Molecular and Cellular Biology.

[4]  Noula Shembade,et al.  TAX1BP1 Restrains Virus-Induced Apoptosis by Facilitating Itch-Mediated Degradation of the Mitochondrial Adaptor MAVS , 2016, Molecular and Cellular Biology.

[5]  I. Hong.  Stimulatory versus suppressive effects of GM-CSF on tumor progression in multiple cancer types , 2016, Experimental & Molecular Medicine.

[6]  M. Rapé,et al.  The increasing complexity of the ubiquitin code , 2016, Nature Cell Biology.

[7]  E. D. De Robertis,et al.  Wnt Signaling Translocates Lys48-Linked Polyubiquitinated Proteins to the Lysosomal Pathway. , 2015, Cell reports.

[8]  Jennifer A. Clark,et al.  NORE1A is a Ras senescence effector that controls the apoptotic/senescent balance of p53 via HIPK2 , 2015, The Journal of cell biology.

[9]  Jun Ma,et al.  APP intracellular domain acts as a transcriptional regulator of miR-663 suppressing neuronal differentiation , 2015, Cell Death and Disease.

[10]  Z. Qin,et al.  DRAM1 regulates apoptosis through increasing protein levels and lysosomal localization of BAX , 2015, Cell Death and Disease.

[11]  D. Kabelitz,et al.  Cell Fate Decisions Regulated by K63 Ubiquitination of Tumor Necrosis Factor Receptor 1 , 2014, Molecular and Cellular Biology.

[12]  Junying Yuan,et al.  Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death , 2013, Nature Reviews Molecular Cell Biology.

[13]  W. Schneider-Brachert,et al.  Membrane Trafficking of Death Receptors: Implications on Signalling , 2013, International journal of molecular sciences.

[14]  S. Mahalingam,et al.  The E3 ubiquitin ligase Itch regulates tumor suppressor protein RASSF5/NORE1 stability in an acetylation-dependent manner , 2013, Cell Death and Disease.

[15]  M. LaVoie,et al.  The ubiquitin E3 ligase parkin regulates the proapoptotic function of Bax , 2012, Proceedings of the National Academy of Sciences.

[16]  L. Cavalli,et al.  Evidence of epigenetic regulation of the tumor suppressor gene cluster flanking RASSF1 in breast cancer cell lines , 2011, Epigenetics.

[17]  John S. Condeelis,et al.  Chemotaxis in cancer , 2011, Nature Reviews Cancer.

[18]  Vishva M. Dixit,et al.  Ubiquitylation in apoptosis: a post-translational modification at the edge of life and death , 2011, Nature Reviews Molecular Cell Biology.

[19]  B. Edelmann,et al.  Subcellular compartmentalization of TNF receptor-1 and CD95 signaling pathways. , 2011, European journal of cell biology.

[20]  J. Shim,et al.  Epigenetic inactivation of the NORE1 gene correlates with malignant progression of colorectal tumors , 2010, BMC Cancer.

[21]  J. Avruch,et al.  Tumor Suppressor Ras Association Domain Family 5 (RASSF5/NORE1) Mediates Death Receptor Ligand-induced Apoptosis* , 2010, The Journal of Biological Chemistry.

[22]  Miriam Davis,et al.  TNF receptor 2 pathway: drug target for autoimmune diseases , 2010, Nature Reviews Drug Discovery.

[23]  R. Youle,et al.  IBRDC2, an IBR‐type E3 ubiquitin ligase, is a regulatory factor for Bax and apoptosis activation , 2010, The EMBO journal.

[24]  A. Angers,et al.  The ubiquitin ligase Itch mediates the antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the truncated C‐terminal portion of Bid , 2010, The FEBS journal.

[25]  Nadir Arber,et al.  Inflammation and colorectal cancer. , 2009, Current opinion in pharmacology.

[26]  Alberto Mantovani,et al.  Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. , 2009, Carcinogenesis.

[27]  D. Calvisi,et al.  NORE1A tumor suppressor candidate modulates p21CIP1 via p53. , 2009, Cancer research.

[28]  Jian Yu,et al.  PUMA is directly activated by NF-κB and contributes to TNF-α-induced apoptosis , 2009, Cell Death and Differentiation.

[29]  F. Balkwill.  Tumour necrosis factor and cancer , 2009, Nature Reviews Cancer.

[30]  R. Xavier,et al.  Rassf Family of Tumor Suppressor Polypeptides* , 2009, Journal of Biological Chemistry.

[31]  Özkan Yildiz,et al.  Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch II , 2008, The EMBO journal.

[32]  J. C. Pratt,et al.  Dynamics of RASSF1A/MOAP-1 Association with Death Receptors , 2008, Molecular and Cellular Biology.

[33]  N. Copeland,et al.  The E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20 , 2008, Nature Immunology.

[34]  David J. Adams,et al.  The Ras-association domain family (RASSF) members and their role in human tumourigenesis , 2007, Biochimica et biophysica acta.

[35]  N. Colburn,et al.  AP-1 a target for cancer prevention. , 2007, Current cancer drug targets.

[36]  M. Karin,et al.  The E3 Ubiquitin Ligase Itch Couples JNK Activation to TNFα-induced Cell Death by Inducing c-FLIPL Turnover , 2006, Cell.

[37]  J. Marvaldi,et al.  Bcl-xL/Bax ratio is altered by IFNγ in TNFα- but not in TRAIL-induced apoptosis in colon cancer cell line , 2005 .

[38]  B. Neel,et al.  The tumor suppressor RASSF1A and MAP-1 link death receptor signaling to Bax conformational change and cell death. , 2005, Molecular cell.

[39]  J. Pober,et al.  Caveolae participate in tumor necrosis factor receptor 1 signaling and internalization in a human endothelial cell line. , 2005, The American journal of pathology.

[40]  G. Watanabe,et al.  Spontaneous regression of lung metastasis in the absence of tumor necrosis factor receptor p55 , 2004, International journal of cancer.

[41]  M. Fraga,et al.  CpG island promoter hypermethylation of the Ras-effector gene NORE1A occurs in the context of a wild-type K-ras in lung cancer , 2004, Oncogene.

[42]  D. Kabelitz,et al.  Compartmentalization of TNF receptor 1 signaling: internalized TNF receptosomes as death signaling vesicles. , 2004, Immunity.

[43]  Linda Hicke,et al.  Regulation of membrane protein transport by ubiquitin and ubiquitin-binding proteins. , 2003, Annual review of cell and developmental biology.

[44]  C. Larsson,et al.  The t(1;3) breakpoint-spanning genes LSAMP and NORE1 are involved in clear cell renal cell carcinomas. , 2003, Cancer cell.

[45]  G. Clark,et al.  The Pro-apoptotic Ras Effector Nore1 May Serve as a Ras-regulated Tumor Suppressor in the Lung* , 2003, Journal of Biological Chemistry.

[46]  J. Tschopp,et al.  Recruitment of TNF Receptor 1 to Lipid Rafts Is Essential for TNFα-Mediated NF-κB Activation , 2003 .

[47]  J. Minna,et al.  NORE1A, a homologue of RASSF1A tumour suppressor gene is inactivated in human cancers , 2003, Oncogene.

[48]  J. Avruch,et al.  RASSF3 and NORE1: identification and cloning of two human homologues of the putative tumor suppressor gene RASSF1 , 2002, Oncogene.

[49]  J. Avruch,et al.  The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1 , 2002, Oncogene.

[50]  R. Xavier,et al.  Identification of a Novel Ras-Regulated Proapoptotic Pathway , 2002, Current Biology.

[51]  E. White,et al.  TNF-alpha signals apoptosis through a bid-dependent conformational change in Bax that is inhibited by E1B 19K. , 2000, Molecular cell.

[52]  S. Jones,et al.  TNF recruits TRADD to the plasma membrane but not the trans-Golgi network, the principal subcellular location of TNF-R1. , 1999, Journal of immunology.

[53]  J. Talmadge,et al.  Immunomodulatory properties of recombinant murine and human tumor necrosis factor. , 1988, Cancer research.

[54]  S. Kashimoto,et al.  Augmented Antitumor Effect of Recombinant Human Interleukin-1α by Indomethacin , 1988 .

[55]  L. Qin,et al.  Promoter methylation and expression of RASSF 1 A genes as predictors of disease progression in colorectal cancer , 2016 .

[56]  V. Dixit,et al.  Regulation of death receptor signaling by the ubiquitin system , 2010, Cell Death and Differentiation.

[57]  Wan-Wan Lin,et al.  Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis , 2009, Nature.

[58]  J. Tschopp,et al.  Recruitment of TNF receptor 1 to lipid rafts is essential for TNFalpha-mediated NF-kappaB activation. , 2003, Immunity.