Single Molecule Imaging of Transcription Factor Binding to DNA in Live Mammalian Cells

[1]  J. McNally,et al.  A benchmark for chromatin binding measurements in live cells , 2012, Nucleic acids research.

[2]  G. Hager,et al.  Complex dynamics of transcription regulation. , 2012, Biochimica et biophysica acta.

[3]  Johan Elf,et al.  The lac Repressor Displays Facilitated Diffusion in Living Cells , 2012, Science.

[4]  J. McNally,et al.  Minimizing the impact of photoswitching of fluorescent proteins on FRAP analysis. , 2012, Biophysical journal.

[5]  U. Vinkemeier,et al.  Activated STAT1 transcription factors conduct distinct saltatory movements in the cell nucleus. , 2011, Biophysical journal.

[6]  A. Diaspro,et al.  Live-cell 3D super-resolution imaging in thick biological samples , 2011, Nature Methods.

[7]  J. Ellenberg,et al.  The quantitative proteome of a human cell line , 2011, Molecular systems biology.

[8]  Daniel A. Colón-Ramos,et al.  Inverted selective plane illumination microscopy (iSPIM) enables coupled cell identity lineaging and neurodevelopmental imaging in Caenorhabditis elegans , 2011, Proceedings of the National Academy of Sciences.

[9]  Lars Hufnagel,et al.  Quantitative fluorescence imaging of protein diffusion and interaction in living cells , 2011, Nature Biotechnology.

[10]  S. Mandrup,et al.  Molecular basis for gene-specific transactivation by nuclear receptors. , 2011, Biochimica et biophysica acta.

[11]  Gene-Wei Li,et al.  Central dogma at the single-molecule level in living cells , 2011, Nature.

[12]  J. Elf,et al.  Single-molecule investigations of the stringent response machinery in living bacterial cells , 2011, Proceedings of the National Academy of Sciences.

[13]  X. Zhuang,et al.  Fast three-dimensional super-resolution imaging of live cells , 2011, Nature Methods.

[14]  M. Davidson,et al.  Rapid three-dimensional isotropic imaging of living cells using Bessel beam plane illumination , 2011, Nature Methods.

[15]  Ulrich Kubitscheck,et al.  Light Sheet Microscopy for Single Molecule Tracking in Living Tissue , 2010, PloS one.

[16]  Davide Mazza,et al.  FRAP and kinetic modeling in the analysis of nuclear protein dynamics: what do we really know? , 2010, Current opinion in cell biology.

[17]  T. Wagner,et al.  Detection of single quantum dots in model organisms with sheet illumination microscopy. , 2009, Biochemical and biophysical research communications.

[18]  Jan Ellenberg,et al.  Molecular crowding affects diffusion and binding of nuclear proteins in heterochromatin and reveals the fractal organization of chromatin , 2009, The EMBO journal.

[19]  John T. Lis,et al.  Defining mechanisms that regulate RNA polymerase II transcription in vivo , 2009, Nature.

[20]  Jan Huisken,et al.  Selective plane illumination microscopy techniques in developmental biology , 2009, Development.

[21]  Kristin L. Hazelwood,et al.  A bright and photostable photoconvertible fluorescent protein for fusion tags , 2009, Nature Methods.

[22]  Marjeta Urh,et al.  HaloTag: a novel protein labeling technology for cell imaging and protein analysis. , 2008, ACS chemical biology.

[23]  Michael Z. Lin,et al.  Improving the photostability of bright monomeric orange and red fluorescent proteins , 2008, Nature Methods.

[24]  Nam Ki Lee,et al.  Single-molecule approach to molecular biology in living bacterial cells. , 2008, Annual review of biophysics.

[25]  J. Lippincott-Schwartz,et al.  High-density mapping of single-molecule trajectories with photoactivated localization microscopy , 2008, Nature Methods.

[26]  M. Tokunaga,et al.  Highly inclined thin illumination enables clear single-molecule imaging in cells , 2008, Nature Methods.

[27]  S. Gasser,et al.  The nuclear envelope and transcriptional control , 2007, Nature Reviews Genetics.

[28]  S. Gygi,et al.  Probing Transcription Factor Dynamics at the Single-Molecule Level in a Living Cell , 2007, Science.

[29]  Florian Müller,et al.  Analysis of binding at a single spatially localized cluster of binding sites by fluorescence recovery after photobleaching. , 2006, Biophysical journal.

[30]  Matthias Rief,et al.  Myosin-V is a mechanical ratchet. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[31]  Jan Ellenberg,et al.  Dissecting the contribution of diffusion and interactions to the mobility of nuclear proteins. , 2006, Biophysical journal.

[32]  Patrick S Daugherty,et al.  Evolutionary optimization of fluorescent proteins for intracellular FRET , 2005, Nature Biotechnology.

[33]  F. Del Bene,et al.  Optical Sectioning Deep Inside Live Embryos by Selective Plane Illumination Microscopy , 2004, Science.

[34]  D. P. Fromm,et al.  Methods of single-molecule fluorescence spectroscopy and microscopy , 2003 .

[35]  James G McNally,et al.  Dynamic behavior of transcription factors on a natural promoter in living cells , 2002, EMBO reports.

[36]  W. Webb,et al.  Precise nanometer localization analysis for individual fluorescent probes. , 2002, Biophysical journal.

[37]  M. Hallek,et al.  Real-Time Single-Molecule Imaging of the Infection Pathway of an Adeno-Associated Virus , 2001, Science.

[38]  S. Simon,et al.  Tracking single proteins within cells. , 2000, Biophysical journal.

[39]  J. McNally,et al.  The glucocorticoid receptor: rapid exchange with regulatory sites in living cells. , 2000, Science.

[40]  Toshio Yanagida,et al.  Single-molecule imaging of EGFR signalling on the surface of living cells , 2000, Nature Cell Biology.

[41]  D. P. King,et al.  Role of the CLOCK protein in the mammalian circadian mechanism. , 1998, Science.

[42]  H Schindler,et al.  Single-molecule microscopy on model membranes reveals anomalous diffusion. , 1997, Biophysical journal.

[43]  P. Herrlich,et al.  IκBα‐independent downregulation of NF‐κB activity by glucocorticoid receptor , 1997, The EMBO journal.

[44]  M. Stallcup,et al.  GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[45]  B. O’Malley,et al.  Molecular interactions of steroid hormone receptor with its enhancer element: Evidence for receptor dimer formation , 1988, Cell.

[46]  W. McGuire,et al.  Human breast cancer: biologically active estrogen receptor in the absence of estrogen? , 1977, Science.

[47]  Carmen Domingo Biology , 1929, Nature.

[48]  H. Vogel,et al.  A general method for the covalent labeling of fusion proteins with small molecules in vivo , 2003, Nature Biotechnology.