Epigenetic interplay between histone modifications and DNA methylation in gene silencing.

[1]  R. Place,et al.  Epigenetic Modifications of RASSF1A Gene through Chromatin Remodeling in Prostate Cancer , 2007, Clinical Cancer Research.

[2]  M. Szyf,et al.  Histone deacetylase inhibitor Trichostatin A induces global and gene-specific DNA demethylation in human cancer cell lines. , 2007, Biochemical pharmacology.

[3]  A. Guidotti,et al.  Histone hyperacetylation induces demethylation of reelin and 67-kDa glutamic acid decarboxylase promoters , 2007, Proceedings of the National Academy of Sciences.

[4]  M. Szyf,et al.  Valproate induces widespread epigenetic reprogramming which involves demethylation of specific genes. , 2007, Carcinogenesis.

[5]  Zdenko Herceg,et al.  Epigenetics and cancer: towards an evaluation of the impact of environmental and dietary factors. , 2007, Mutagenesis.

[6]  M. Fraga,et al.  DNA methyltransferases control telomere length and telomere recombination in mammalian cells , 2006, Nature Cell Biology.

[7]  M. Bulger,et al.  Hyperacetylated Chromatin Domains: Lessons from Heterochromatin* , 2005, Journal of Biological Chemistry.

[8]  Martha R. Stampfer,et al.  Chromatin Inactivation Precedes De Novo DNA Methylation during the Progressive Epigenetic Silencing of the RASSF1A Promoter , 2005, Molecular and Cellular Biology.

[9]  Z. Herceg,et al.  Rendez-vous at Mitosis: TRRAPed in the Chromatin , 2005, Cell cycle.

[10]  X. de la Cruz,et al.  Do protein motifs read the histone code? , 2005, BioEssays : news and reviews in molecular, cellular and developmental biology.

[11]  Frank D Gilliland,et al.  Plutonium targets the p16 gene for inactivation by promoter hypermethylation in human lung adenocarcinoma. , 2004, Carcinogenesis.

[12]  Peter A. Jones,et al.  Epigenetics in human disease and prospects for epigenetic therapy , 2004, Nature.

[13]  A. Feinberg,et al.  The history of cancer epigenetics , 2004, Nature Reviews Cancer.

[14]  Xiang-Jiao Yang The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseases. , 2004, Nucleic acids research.

[15]  G. Felsenfeld,et al.  Silencing of transgene transcription precedes methylation of promoter DNA and histone H3 lysine 9 , 2004, The EMBO journal.

[16]  S. Katiyar,et al.  Exceptionally high protection of photocarcinogenesis by topical application of (--)-epigallocatechin-3-gallate in hydrophilic cream in SKH-1 hairless mouse model: relationship to inhibition of UVB-induced global DNA hypomethylation. , 2003, Neoplasia.

[17]  Yan Yan,et al.  Analysis of specific lysine histone H3 and H4 acetylation and methylation status in clones of cells with a gene silenced by nickel exposure. , 2003, Toxicology and applied pharmacology.

[18]  Jiuhong Kang,et al.  Nickel-induced histone hypoacetylation: the role of reactive oxygen species. , 2003, Toxicological sciences : an official journal of the Society of Toxicology.

[19]  T. Jenuwein,et al.  Suv39h-Mediated Histone H3 Lysine 9 Methylation Directs DNA Methylation to Major Satellite Repeats at Pericentric Heterochromatin , 2003, Current Biology.

[20]  M. Waalkes,et al.  Effects of cadmium on DNA-(Cytosine-5) methyltransferase activity and DNA methylation status during cadmium-induced cellular transformation. , 2003, Experimental cell research.

[21]  T. Kouzarides,et al.  The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase. , 2003, Nucleic acids research.

[22]  David J Brenner,et al.  Past exposure to densely ionizing radiation leaves a unique permanent signature in the genome. , 2003, American journal of human genetics.

[23]  A. Bird,et al.  Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals , 2003, Nature Genetics.

[24]  Tony Kouzarides,et al.  The Methyl-CpG-binding Protein MeCP2 Links DNA Methylation to Histone Methylation* , 2003, The Journal of Biological Chemistry.

[25]  A. Wolffe,et al.  The barrier function of an insulator couples high histone acetylation levels with specific protection of promoter DNA from methylation. , 2002, Genes & development.

[26]  Peter A. Jones,et al.  The fundamental role of epigenetic events in cancer , 2002, Nature Reviews Genetics.

[27]  J. Froines,et al.  Sodium arsenite administration via drinking water increases genome-wide and Ha-ras DNA hypomethylation in methyl-deficient C57BL/6J mice. , 2002, Carcinogenesis.

[28]  Bert Vogelstein,et al.  DNMT1 and DNMT3b cooperate to silence genes in human cancer cells , 2002, Nature.

[29]  J. P. Jackson,et al.  Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase , 2002, Nature.

[30]  S. Elgin,et al.  Epigenetic Codes for Heterochromatin Formation and Silencing Rounding up the Usual Suspects , 2002, Cell.

[31]  E. Selker,et al.  A histone H3 methyltransferase controls DNA methylation in Neurospora crassa , 2001, Nature.

[32]  B. Cairns Emerging roles for chromatin remodeling in cancer biology. , 2001, Trends in cell biology.

[33]  Nathan M. Springer,et al.  Maize Chromomethylase Zea methyltransferase2 Is Required for CpNpG Methylation , 2001, The Plant Cell Online.

[34]  J. Bender,et al.  Arabidopsis cmt3 chromomethylase mutations block non-CG methylation and silencing of an endogenous gene. , 2001, Genes & development.

[35]  A. Wolffe,et al.  Chromatin remodeling: why it is important in cancer , 2001, Oncogene.

[36]  T. Kouzarides,et al.  Dnmt3a binds deacetylases and is recruited by a sequence‐specific repressor to silence transcription , 2001, The EMBO journal.

[37]  J. P. Jackson,et al.  Requirement of CHROMOMETHYLASE3 for Maintenance of CpXpG Methylation , 2001, Science.

[38]  E. Selker,et al.  Emerging connections between DNA methylation and histone acetylation , 2001, Cellular and Molecular Life Sciences CMLS.

[39]  A. West,et al.  Insulators and boundaries: versatile regulatory elements in the eukaryotic genome. , 2001, Science.

[40]  M. Groudine,et al.  Genomic Targeting of Methylated DNA: Influence of Methylation on Transcription, Replication, Chromatin Structure, and Histone Acetylation , 2000, Molecular and Cellular Biology.

[41]  Michael Grunstein,et al.  Global histone acetylation and deacetylation in yeast , 2000, Nature.

[42]  S. Baylin,et al.  DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci , 2000, Nature Genetics.

[43]  M. Waalkes Cadmium carcinogenesis in review. , 2000, Journal of inorganic biochemistry.

[44]  M. Kuo,et al.  Nickel compounds are novel inhibitors of histone H4 acetylation. , 2000, Cancer research.

[45]  W. Reik,et al.  Dissecting de novo methylation , 1999, Nature Genetics.

[46]  A. Bird,et al.  Methylation-Induced Repression— Belts, Braces, and Chromatin , 1999, Cell.

[47]  D. Haber,et al.  DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development , 1999, Cell.

[48]  Paul Tempst,et al.  MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex , 1999, Nature Genetics.

[49]  E. Ballestar,et al.  Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation , 1999, Nature Genetics.

[50]  V. Colot,et al.  Eukaryotic DNA methylation as an evolutionary device , 1999, BioEssays : news and reviews in molecular, cellular and developmental biology.

[51]  T. Hashimshony,et al.  DNA methylation models histone acetylation , 1998, Nature.

[52]  J. Strouboulis,et al.  Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription , 1998, Nature Genetics.

[53]  Colin A. Johnson,et al.  Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex , 1998, Nature.

[54]  S. Henikoff,et al.  A DNA methyltransferase homolog with a chromodomain exists in multiple polymorphic forms in Arabidopsis. , 1998, Genetics.

[55]  M. Johnson,et al.  Graft-versus-host reactions in dermatology. , 1998, Journal of the American Academy of Dermatology.

[56]  Wolf Reik,et al.  Genomic imprinting: Making sense or antisense? , 1997, Nature.

[57]  B. Diwan,et al.  Association of arsenic-induced malignant transformation with DNA hypomethylation and aberrant gene expression. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[58]  E. Selker,et al.  DNA methylation inhibits elongation but not initiation of transcription in Neurospora crassa. , 1997, Genes & development.

[59]  D. Forbes,et al.  Mitotic repression of the transcriptional machinery. , 1997, Trends in biochemical sciences.

[60]  M. Pazin,et al.  What's Up and Down with Histone Deacetylation and Transcription? , 1997, Cell.

[61]  Stefan U Kass,et al.  DNA methylation directs a time-dependent repression of transcription initiation , 1997, Current Biology.

[62]  R. Jaenisch,et al.  De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells. , 1996, Development.

[63]  Y. W. Lee,et al.  Carcinogenic nickel silences gene expression by chromatin condensation and DNA methylation: a new model for epigenetic carcinogens , 1995, Molecular and cellular biology.

[64]  M A Weinstock,et al.  Nonmelanoma skin cancer in the United States: incidence. , 1994, Journal of the American Academy of Dermatology.

[65]  A. Bird,et al.  Dissection of the methyl-CpG binding domain from the chromosomal protein MeCP2. , 1993, Nucleic acids research.

[66]  How-Ran Guo,et al.  The incidence of bladder cancer in the black foot disease endemic area in Taiwan. , 1993, British journal of urology.

[67]  T. Kuo,et al.  Cancer potential in liver, lung, bladder and kidney due to ingested inorganic arsenic in drinking water. , 1992, British Journal of Cancer.

[68]  A. Bird,et al.  Characterization of MeCP2, a vertebrate DNA binding protein with affinity for methylated DNA. , 1992, Nucleic acids research.

[69]  Rudolf Jaenisch,et al.  Targeted mutation of the DNA methyltransferase gene results in embryonic lethality , 1992, Cell.

[70]  J. Barrett,et al.  Senescence of nickel-transformed cells by an X chromosome: possible epigenetic control. , 1991, Science.

[71]  S. Iguchi-Ariga,et al.  CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation. , 1989, Genes & development.

[72]  A. Graessmann,et al.  Chromatin structure is required to block transcription of the methylated herpes simplex virus thymidine kinase gene. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[73]  Howard Cedar,et al.  DNA methylation affects the formation of active chromatin , 1986, Cell.

[74]  A. Lilienfeld,et al.  Lung cancer among pesticide workers exposed to inorganic arsenicals. , 1979, Archives of environmental health.

[75]  L. G. Morgan,et al.  Cancers of the Lung and Nasal Sinuses in Nickel Workers , 1970, British Journal of Cancer.

[76]  A. Feinberg,et al.  The epigenetic progenitor origin of human cancer , 2006, Nature Reviews Genetics.

[77]  Andrew J. Bannister,et al.  Histone methylation: recognizing the methyl mark. , 2004, Methods in enzymology.

[78]  A. Bird DNA methylation patterns and epigenetic memory. , 2002, Genes & development.

[79]  Luke Hughes-Davies,et al.  DNA methyltransferase Dnmt1 associates with histone deacetylase activity , 2000, Nature Genetics.

[80]  J. Rowley,et al.  The critical role of chromosome translocations in human leukemias. , 1998, Annual review of genetics.