A Comparative Study of Existing Machine Learning Approaches for Parkinson's Disease Detection

ABSTRACT Parkinson's disease (PD) has affected millions of people worldwide and is more prevalent in people, over the age of 50. Even today, with many technologies and advancements, early detection of this disease remains a challenge. This necessitates a need for the machine learning-based automatic approaches that help clinicians to detect this disease accurately in its early stage. Thus, the focus of this research paper is to provide an insightful survey and compare the existing computational intelligence techniques used for PD detection. To save time and increase treatment efficiency, classification has found its place in PD detection. The existing knowledge review indicates that many classification algorithms have been used to achieve better results, but the problem is to identify the most efficient classifier for PD detection. The challenge in identifying the most appropriate classification algorithm lies in their application on local dataset. Thus, in this paper three types of classifiers, namely, Multilayer Perceptron, Support Vector Machine and K-nearest neighbor have been discussed on the benchmark (voice) dataset to compare and to know which of these classifiers is the most efficient and accurate for PD classification. The Voice input dataset for these classifiers has been obtained from UCI machine learning repository. ANN with Levenberg–Marquardt algorithm was found to be the best classifier, having highest classification accuracy (95.89%). Moreover, we compared our results with those obtained by Resul Das [“A comparison of multiple classification methods for diagnosis of Parkinson Disease,” Expert Systems and applications, vol. 37, pp 1568–1572, 2010].

[1]  J. Jankovic,et al.  Movement Disorder Society‐sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS‐UPDRS): Scale presentation and clinimetric testing results , 2008, Movement disorders : official journal of the Movement Disorder Society.

[2]  Tipu Z. Aziz,et al.  Parkinson's Disease tremor classification - A comparison between Support Vector Machines and neural networks , 2012, Expert Syst. Appl..

[3]  Cemal Hanilçi,et al.  A comparison of regression methods for remote tracking of Parkinson's disease progression , 2012, Expert Syst. Appl..

[4]  M. Politis,et al.  Imaging the Nonmotor Symptoms in Parkinson's Disease. , 2017, International review of neurobiology.

[5]  S. Sorbi,et al.  Nonmotor Symptoms of Parkinson's Disease , 2017, Parkinson's disease.

[6]  Sundaram Suresh,et al.  A novel PBL-McRBFN-RFE approach for identification of critical brain regions responsible for Parkinson's disease , 2014, Expert Syst. Appl..

[7]  Freddie Åström,et al.  A parallel neural network approach to prediction of Parkinson's Disease , 2011, Expert Syst. Appl..

[8]  Sang-Hong Lee,et al.  Parkinson's disease classification using gait characteristics and wavelet-based feature extraction , 2012, Expert Syst. Appl..

[9]  Özge Uncu,et al.  A novel feature selection approach: Combining feature wrappers and filters , 2007, Inf. Sci..

[10]  M. Esmel ElAlami A filter model for feature subset selection based on genetic algorithm , 2009, Knowl. Based Syst..

[11]  Juan Manuel Górriz,et al.  Automatic detection of Parkinsonism using significance measures and component analysis in DaTSCAN imaging , 2014, Neurocomputing.

[12]  A. Lang,et al.  Parkinson's disease. First of two parts. , 1998, The New England journal of medicine.

[13]  Ahmed Hammouch,et al.  Voice assessments for detecting patients with Parkinson’s diseases using PCA and NPCA , 2016, Int. J. Speech Technol..

[14]  D B Calne,et al.  Is idiopathic parkinsonism the consequence of an event or a process? , 1994, Neurology.

[15]  M. Breteler,et al.  Epidemiology of Parkinson's disease , 2006, The Lancet Neurology.

[16]  M. Hariharan,et al.  A new hybrid intelligent system for accurate detection of Parkinson's disease , 2014, Comput. Methods Programs Biomed..

[17]  Irnad Irnad,et al.  PENGARUH LINGKUNGAN KERJA KELOMPOK TANI DAN PERANAN SUMBERDAYA KONTAK TANI TERHADAP KINERJA PETANI DESA SIDO URIP KABUPATEN BENGKULU UTARA , 2018, Naturalis: Jurnal Penelitian Pengelolaan Sumber Daya Alam dan Lingkungan.

[18]  Concha Bielza,et al.  Unveiling relevant non-motor Parkinson's disease severity symptoms using a machine learning approach , 2013, Artif. Intell. Medicine.

[19]  Til Aach,et al.  Challenges of medical image processing , 2011, Computer Science - Research and Development.

[20]  Wei Zeng,et al.  Classification of neurodegenerative diseases using gait dynamics via deterministic learning , 2015, Inf. Sci..

[21]  A Schrag,et al.  How does Parkinson's disease affect quality of life? A comparison with quality of life in the general population , 2000, Movement disorders : official journal of the Movement Disorder Society.

[22]  Kuncheng Li,et al.  Changes of functional connectivity of the motor network in the resting state in Parkinson's disease , 2009, Neuroscience Letters.

[23]  Faculty Member,et al.  A Decision Support System for Parkinson's Disease Diagnosis using Classification and Regression Tree , 2012 .

[24]  Hyunsoo Yoon,et al.  Algorithm learning based neural network integrating feature selection and classification , 2013, Expert Syst. Appl..

[25]  Sundaram Suresh,et al.  Parkinson's disease prediction using gene expression - A projection based learning meta-cognitive neural classifier approach , 2013, Expert Syst. Appl..

[26]  Tipu Z. Aziz,et al.  Prediction of Parkinson's disease tremor onset using radial basis function neural networks , 2010, Expert Syst. Appl..

[27]  Resul Das,et al.  A comparison of multiple classification methods for diagnosis of Parkinson disease , 2010, Expert Syst. Appl..

[28]  Narayana Prasad Padhy,et al.  Cuckoo Search Algorithm for Emission Reliable Economic Multi-objective Dispatch Problem , 2014 .

[29]  Renu Vig,et al.  Dynamic PSO-Based Associative Classifier for Medical Datasets , 2014 .

[30]  Academisch Proefschrift,et al.  UvA-DARE ( Digital Academic Repository ) Clinimetrics , clinical profile and prognosis in early Parkinson ’ s disease , 2009 .

[31]  R W Angel,et al.  Control of movement in Parkinson's disease. , 1970, Brain : a journal of neurology.

[32]  Madhuri Behari,et al.  Regions-of-interest based automated diagnosis of Parkinson's disease using T1-weighted MRI , 2015, Expert Syst. Appl..

[33]  Lakshminarayanan Samavedham,et al.  Unsupervised learning based feature extraction for differential diagnosis of neurodegenerative diseases: A case study on early-stage diagnosis of Parkinson disease , 2015, Journal of Neuroscience Methods.

[34]  A. Cerasa,et al.  Machine learning on brain MRI data for differential diagnosis of Parkinson's disease and Progressive Supranuclear Palsy , 2014, Journal of Neuroscience Methods.

[35]  U. Bonuccelli,et al.  Mild cognitive impairment and cognitive reserve in Parkinson's disease. , 2011, Parkinsonism & related disorders.

[36]  Sundaram Suresh,et al.  Identification of brain regions responsible for Alzheimer's disease using a Self-adaptive Resource Allocation Network , 2012, Neural Networks.

[37]  Chin-Hsing Chen,et al.  A vision-based regression model to evaluate Parkinsonian gait from monocular image sequences , 2012, Expert Syst. Appl..

[38]  Ron Kohavi,et al.  Wrappers for Feature Subset Selection , 1997, Artif. Intell..

[39]  Gang Wang,et al.  An efficient diagnosis system for detection of Parkinson's disease using fuzzy k-nearest neighbor approach , 2013, Expert Syst. Appl..

[40]  Max A. Little,et al.  Exploiting Nonlinear Recurrence and Fractal Scaling Properties for Voice Disorder Detection , 2007, Biomedical engineering online.

[41]  Mohammad Bagher Menhaj,et al.  Training feedforward networks with the Marquardt algorithm , 1994, IEEE Trans. Neural Networks.

[42]  Paola Piccini,et al.  Functional brain imaging in the differential diagnosis of Parkinson's disease , 2004, The Lancet Neurology.

[43]  Donghai Guan,et al.  A Review of Ensemble Learning Based Feature Selection , 2014 .

[44]  K. Gwinn‐Hardy,et al.  The role of radiotracer imaging in Parkinson disease , 2005, Neurology.

[45]  B. Park,et al.  Choice of neighbor order in nearest-neighbor classification , 2008, 0810.5276.

[46]  Carlos J. Perez,et al.  A two-stage variable selection and classification approach for Parkinson's disease detection by using voice recording replications , 2017, Comput. Methods Programs Biomed..

[47]  Max A. Little,et al.  Suitability of Dysphonia Measurements for Telemonitoring of Parkinson's Disease , 2008, IEEE Transactions on Biomedical Engineering.

[48]  Vladimir Naumovich Vapni The Nature of Statistical Learning Theory , 1995 .

[49]  Xiaoming Xu,et al.  A hybrid genetic algorithm for feature selection wrapper based on mutual information , 2007, Pattern Recognit. Lett..

[50]  Anupam Shukla,et al.  A survey of nature-inspired algorithms for feature selection to identify Parkinson's disease , 2017, Comput. Methods Programs Biomed..

[51]  C. Good,et al.  Differentiation of atypical parkinsonian syndromes with routine MRI , 2000, Neurology.

[52]  M. Morris Movement disorders in people with Parkinson disease: a model for physical therapy. , 2000, Physical therapy.