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Genomics: Encyclopaedia of humble DNA

Researchers of the ENCODE consortium have analysed 1% of the human genome. Their findings bring us a step closer to understanding the role of the vast amount of obscure DNA that does not function as genes.

John M. Greally | J. Greally

[1] T. Hudson,et al. A genome-wide association study identifies novel risk loci for type 2 diabetes , 2007, Nature.

[2] Mark Gerstein,et al. DNA replication-timing analysis of human chromosome 22 at high resolution and different developmental states. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[3] A. Reymond,et al. Conserved non-genic sequences — an unexpected feature of mammalian genomes , 2005, Nature Reviews Genetics.

[4] Marcia M. Nizzari,et al. Genome-Wide Association Analysis Identifies Loci for Type 2 Diabetes and Triglyceride Levels , 2007, Science.

[5] J. Gulcher,et al. A variant in CDKAL1 influences insulin response and risk of type 2 diabetes , 2007, Nature Genetics.

[6] Paul T. Groth,et al. The ENCODE (ENCyclopedia Of DNA Elements) Project , 2004, Science.

[7] G. Abecasis,et al. A Genome-Wide Association Study of Type 2 Diabetes in Finns Detects Multiple Susceptibility Variants , 2007, Science.

[8] William Stafford Noble,et al. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project , 2007, Nature.

[9] M. O’Neill. The influence of non-coding RNAs on allele-specific gene expression in mammals. , 2005, Human molecular genetics.