A pre-task resting condition neither ‘baseline’ nor ‘zero’

This study introduce the comparison of a 'reference state' versus a resting condition (zero), defined upon normative developmental equations. We compared pre-task 'resting' data from healthy individuals with the Normative Cuban digital resting EEG-database recently calculated for VARETA (qEEG/VARETA). The results allowed us to state that a 'pre-task resting conditions' exists as a state beyond the 'zero' or 'baseline' condition. The pre-task 'resting' condition is never truly 'at rest', however most of the previous published fMRI/PET studies assumed such a pre-task condition as reference/baseline condition. By defining different 'resting states' by qEEG/VARETA analyses, we have a potential methodology which can define resting state conditions and to be sure that they are consistent when comparing within group analyses across tasks or between groups either void of task or for task specific conditions.

[1]  N. Trujillo-Barreto,et al.  3D Statistical Parametric Mapping of EEG Source Spectra by Means of Variable Resolution Electromagnetic Tomography (VARETA) , 2001, Clinical EEG.

[2]  E. John,et al.  Conventional and quantitative electroencephalography in psychiatry. , 1999, The Journal of neuropsychiatry and clinical neurosciences.

[3]  A. von Stein,et al.  Different frequencies for different scales of cortical integration: from local gamma to long range alpha/theta synchronization. , 2000, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[4]  E. John The neurophysics of consciousness , 2002, Brain Research Reviews.

[5]  M. Scherg,et al.  Intracerebral Sources of Human Auditory-Evoked Potentials , 1999, Audiology and Neurotology.

[6]  B. Mazoyer,et al.  Cortical networks for working memory and executive functions sustain the conscious resting state in man , 2001, Brain Research Bulletin.

[7]  E. Aubert,et al.  Induced oscillations and the distributed cortical sources during the Wisconsin card sorting test performance in schizophrenic patients: new clues to neural connectivity. , 2003, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[8]  A. Kondacs,et al.  Long-term intra-individual variability of the background EEG in normals , 1999, Clinical Neurophysiology.

[9]  Vinod Menon,et al.  Functional connectivity in the resting brain: A network analysis of the default mode hypothesis , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[10]  Matthias M. Müller,et al.  Effects of spatial selective attention on the steady-state visual evoked potential in the 20-28 Hz range. , 1998, Brain research. Cognitive brain research.

[11]  G L Shulman,et al.  INAUGURAL ARTICLE by a Recently Elected Academy Member:A default mode of brain function , 2001 .

[12]  Jorge Bosch-Bayard,et al.  Wisconsin card sorting test synchronizes the prefrontal, temporal and posterior association cortex in different frequency ranges and extensions , 2002, Human brain mapping.

[13]  Craig E. L. Stark,et al.  When zero is not zero: The problem of ambiguous baseline conditions in fMRI , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[14]  E. John,et al.  Localization of Deep White Matter Lymphoma Using VARETA: A Case Study , 2001, Clinical EEG.

[15]  Juan Silva-Pereyra,et al.  EEG changes during word and figure categorization , 2001, Clinical Neurophysiology.

[16]  Nelson J. Trujillo-Barreto,et al.  Bayesian model averaging in EEG/MEG imaging , 2004, NeuroImage.