Significance of early cellular and molecular changes for the evolution and the prevention of liver cancer

In cooperation with: Susanne Brendler-Schwaab, Harald Enzmann, Ludwig Schladt, Toxicology Rodent Studies and Genetic Toxicology, Bayer AG, Wuppertal; Erhard Deml, Doris Oesterle, Institute of Toxicology of the National Research Center for Environment and Health, Neuherberg; Karin Küttler, Werner Mellert, Product Safety Regulations, Toxicology and Ecology, BASF AG, Ludwigshafen; Oliver Mönnikes, Michael Schwarz, Department of Toxicology, Universitiy of Tübingen; Eikichi Okada, Sakae Taira, Department of Gastroenterology, Tokyo Universitiy School of Medicine, Tokyo, Japan; Masao Omata, Department of Pathology, Toyama Medical-Pharmacological University, Toyama, Japan; Ulrike Protzer, Department of Virology (Hygiene Institute), University Hospital, Heidelberg; Kunio Tagegoshi, Tagegoshi Internal Medicine Clinic, Takaoka, Japan; DKFZ: Carina Ittrich, Annette Kopp-Schneider, Central Unit of Biostatistics; Doris Mayer, Research Group Hormones and Signal Transduction; Claus Schröder, Division Virus-Host Interactions; Thomas Flohr, Heinz Werner Thielmann, Division Interaction of Chemicals with Cellular Macromolecules; Andreas Hunzicker, Division Cell Biology.