Development Of A Digital Video Subtraction System For Intravenous Angiography

This paper represents the third presentation to the SPIE that has dealt with our research activities in photoelectronic radiology and intravenous angiography. The earlier papers have been published in Volumes 1271 and 1642 of the Proceedings, and cover the evolution of the technical facilities and associated radiographic images obtained with dogs. We have now reached a level of competence suitable for the examination of patients, and we present examples of the images obtained to date. Although the research activity reported here began with the task of non-invasive imaging of arteries for the early detection of atherosclerosis, it is becoming increasingly clear that the method is applicable to all areas of the body to which angiography is being currently applied. Furthermore, with the advantages of this technique, new applications are being developed. Thus, we are now beginning examination of animals and patients to determine the utility of intravenous (non-invasive) angiography for examination of the head, coronary arteries, heart, lungs, kidneys, and extremities, and look forward with considerable optimism to the results.