High-Throughput Screening and Proteomic Characterization of Compounds Targeting Myeloid-Derived Suppressor Cells
暂无分享,去创建一个
B. Kuster | Hannes Hahne | M. Klingenspor | E. Petrova | Christina E. M. Schindler | J. Pieck | L. Helming | J. Mergner | T. Fromme | Alessandro Prestipino | Severin Lechner | H. Boehm | Johannes Krumm | Marshall L. Deline | Dominik Steinbrunn | Lisa Koetzner
[1] Wei Lu,et al. Targeting ACYP1-mediated glycolysis reverses lenvatinib resistance and restricts hepatocellular carcinoma progression. , 2023, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.
[2] Xiuzhen Chen,et al. Solvent‐induced proteome profiling for proteomic quantitation and target discovery of small molecular drugs , 2023, Proteomics.
[3] Z. Yao,et al. ACYP1 Is a Pancancer Prognostic Indicator and Affects the Immune Microenvironment in LIHC , 2022, Frontiers in Oncology.
[4] Aubry K. Miller,et al. Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target , 2022, Nature Chemical Biology.
[5] Xin Lu,et al. Enhancing immune checkpoint blockade therapy of genitourinary malignancies by co-targeting PMN-MDSCs. , 2022, Biochimica et biophysica acta. Reviews on cancer.
[6] X. Wan,et al. Regulating Histone Deacetylase Signaling Pathways of Myeloid-Derived Suppressor Cells Enhanced T Cell-Based Immunotherapy , 2022, Frontiers in Immunology.
[7] Yantong Lu,et al. Targeting Myeloid-Derived Suppressor Cells to Enhance the Antitumor Efficacy of Immune Checkpoint Blockade Therapy , 2021, Frontiers in Immunology.
[8] P. Paci,et al. Polymorphonuclear myeloid-derived suppressor cells impair the anti-tumor efficacy of GD2.CAR T-cells in patients with neuroblastoma , 2021, Journal of Hematology & Oncology.
[9] Wenxin Wang,et al. Regulatory Effects of Histone Deacetylase Inhibitors on Myeloid-Derived Suppressor Cells , 2021, Frontiers in Immunology.
[10] G. Friedlander,et al. CD74 is a regulator of hematopoietic stem cell maintenance , 2021, PLoS biology.
[11] J. Tavernier,et al. Interleukin-1 as Innate Mediator of T Cell Immunity , 2021, Frontiers in Immunology.
[12] T. Fukumoto,et al. Selective targeting of different populations of myeloid-derived suppressor cells by histone deacetylase inhibitors , 2020, Cancer Immunology, Immunotherapy.
[13] C. Zahnow,et al. Epigenetic therapy inhibits metastases by disrupting premetastatic niches , 2020, Nature.
[14] Bernhard Hemmer,et al. Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC–MS/MS , 2020, Nature Communications.
[15] M. Ahluwalia,et al. Glioblastoma Myeloid-Derived Suppressor Cell Subsets Express Differential Macrophage Migration Inhibitory Factor Receptor Profiles That Can Be Targeted to Reduce Immune Suppression , 2019, bioRxiv.
[16] Mario Leutert,et al. R2‐P2 rapid‐robotic phosphoproteomics enables multidimensional cell signaling studies , 2019, Molecular systems biology.
[17] A. Obenauf,et al. Allies or Enemies—The Multifaceted Role of Myeloid Cells in the Tumor Microenvironment , 2019, Front. Immunol..
[18] A. Zhitkovich. N-Acetylcysteine: Antioxidant, Aldehyde Scavenger, and More. , 2019, Chemical research in toxicology.
[19] S. Carr,et al. TMT Labeling for the Masses: A Robust and Cost-efficient, In-solution Labeling Approach* , 2019, Molecular & Cellular Proteomics.
[20] J. Santibañez,et al. How to measure the immunosuppressive activity of MDSC: assays, problems and potential solutions , 2019, Cancer Immunology, Immunotherapy.
[21] J. Pollard,et al. Deciphering myeloid-derived suppressor cells: isolation and markers in humans, mice and non-human primates , 2019, Cancer Immunology, Immunotherapy.
[22] J. Utikal,et al. Immunosuppression mediated by myeloid-derived suppressor cells (MDSCs) during tumour progression , 2018, British Journal of Cancer.
[23] Martin Eisenacher,et al. The PRIDE database and related tools and resources in 2019: improving support for quantification data , 2018, Nucleic Acids Res..
[24] Christopher S. Hughes,et al. Single-pot, solid-phase-enhanced sample preparation for proteomics experiments , 2018, Nature Protocols.
[25] Kang-Yun Lee,et al. Correction: S100A9+ MDSC and TAM-mediated EGFR-TKI resistance in lung adenocarcinoma: the role of RELB , 2018, Oncotarget.
[26] L. Travassos,et al. Blockade of MIF–CD74 Signalling on Macrophages and Dendritic Cells Restores the Antitumour Immune Response Against Metastatic Melanoma , 2018, Front. Immunol..
[27] P. Lowenstein,et al. Melanoma induced immunosuppression is mediated by hematopoietic dysregulation , 2018, Oncoimmunology.
[28] M. Zöller. Janus-Faced Myeloid-Derived Suppressor Cell Exosomes for the Good and the Bad in Cancer and Autoimmune Disease , 2018, Front. Immunol..
[29] D. Gabrilovich,et al. Myeloid-derived suppressor cells coming of age , 2018, Nature Immunology.
[30] G. Lesinski,et al. Targeted Therapies: Immunologic Effects and Potential Applications Outside of Cancer , 2018, Journal of clinical pharmacology.
[31] Bin Zhang,et al. CD39/CD73 upregulation on myeloid-derived suppressor cells via TGF-β-mTOR-HIF-1 signaling in patients with non-small cell lung cancer , 2017, Oncoimmunology.
[32] Xiaodong Zhang,et al. The biological function and significance of CD74 in immune diseases , 2017, Inflammation Research.
[33] Matthias Schröder,et al. Identification of inhibitors of myeloid-derived suppressor cells activity through phenotypic chemical screening , 2017, Oncoimmunology.
[34] Jüergen Cox,et al. The MaxQuant computational platform for mass spectrometry-based shotgun proteomics , 2016, Nature Protocols.
[35] J. Lee,et al. The expression profiles and regulation of PD-L1 in tumor-induced myeloid-derived suppressor cells , 2016, Oncoimmunology.
[36] Marco Y. Hein,et al. The Perseus computational platform for comprehensive analysis of (prote)omics data , 2016, Nature Methods.
[37] Y. Teng,et al. Exosomes miR-126a released from MDSC induced by DOX treatment promotes lung metastasis , 2016, Oncogene.
[38] S. Mocellin,et al. Activated T cells sustain myeloid-derived suppressor cell-mediated immune suppression , 2015, Oncotarget.
[39] Jie Zhou,et al. Norepinephrine-induced myeloid-derived suppressor cells block T-cell responses via generation of reactive oxygen species , 2015, Immunopharmacology and immunotoxicology.
[40] B. Kuster,et al. Optimized chemical proteomics assay for kinase inhibitor profiling. , 2015, Journal of proteome research.
[41] Hanspeter Pfister,et al. UpSet: Visualization of Intersecting Sets , 2014, IEEE Transactions on Visualization and Computer Graphics.
[42] Marco Y. Hein,et al. Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ * , 2014, Molecular & Cellular Proteomics.
[43] A. Wilk,et al. Subpopulations of myeloid‐derived suppressor cells impair T cell responses through independent nitric oxide‐related pathways , 2014, International journal of cancer.
[44] Edward L. Huttlin,et al. MultiNotch MS3 Enables Accurate, Sensitive, and Multiplexed Detection of Differential Expression across Cancer Cell Line Proteomes , 2014, Analytical chemistry.
[45] A. Mahmoud,et al. Warburg effect increases steady-state ROS condition in cancer cells through decreasing their antioxidant capacities (anticancer effects of 3-bromopyruvate through antagonizing Warburg effect). , 2013, Medical hypotheses.
[46] Q. Hu,et al. Myeloid-derived suppressor cell development is regulated by a STAT/IRF-8 axis. , 2013, The Journal of clinical investigation.
[47] Bernhard Kuster,et al. DMSO enhances electrospray response, boosting sensitivity of proteomic experiments , 2013, Nature Methods.
[48] P. De Baetselier,et al. Instruction of myeloid cells by the tumor microenvironment , 2012, Oncoimmunology.
[49] C. Drake,et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. , 2012, The New England journal of medicine.
[50] David C. Smith,et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. , 2012, The New England journal of medicine.
[51] N. L. La Thangue,et al. HDAC inhibitors in cancer biology: emerging mechanisms and clinical applications , 2012, Immunology and cell biology.
[52] Jonathan B. Mitchem,et al. Myeloid-derived suppressor cells: general characteristics and relevance to clinical management of pancreatic cancer. , 2011, Current cancer drug targets.
[53] P. Grandi,et al. Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes , 2011, Nature Biotechnology.
[54] D. Schadendorf,et al. Improved survival with ipilimumab in patients with metastatic melanoma. , 2010, The New England journal of medicine.
[55] B. Rini,et al. Direct and differential suppression of myeloid-derived suppressor cell subsets by sunitinib is compartmentally constrained. , 2010, Cancer research.
[56] Srinivas Nagaraj,et al. Myeloid-derived suppressor cells as regulators of the immune system , 2009, Nature Reviews Immunology.
[57] D. Foell,et al. Proinflammatory S100 Proteins Regulate the Accumulation of Myeloid-Derived Suppressor Cells1 , 2008, The Journal of Immunology.
[58] P. Rodriguez,et al. Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives , 2008, Immunological reviews.
[59] Z. Trajanoski,et al. Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome , 2006, Science.
[60] C. Divino,et al. Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host. , 2006, Cancer research.
[61] V. Bronte,et al. Regulation of immune responses by L-arginine metabolism , 2005, Nature Reviews Immunology.
[62] Christine Brun,et al. In silico prediction of protein-protein interactions in human macrophages , 2001, BMC Research Notes.
[63] M. Shurin,et al. Targeting Myeloid-Derived Suppressor Cells in Cancer. , 2017, Advances in experimental medicine and biology.
[64] D. Gabrilovich,et al. Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function. , 2011, Trends in immunology.
[65] Fu-Tsai Chung,et al. Population alterations of l-arginase- and inducible nitric oxide synthase-expressed CD11b+/CD14−/CD15+/CD33+ myeloid-derived suppressor cells and CD8+ T lymphocytes in patients with advanced-stage non-small cell lung cancer , 2009, Journal of Cancer Research and Clinical Oncology.
[66] M. Nishimura,et al. Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin–cyclophosphamide chemotherapy , 2008, Cancer Immunology, Immunotherapy.
[67] M. Colombo,et al. The terminology issue for myeloid-derived suppressor cells. , 2007, Cancer research.
[68] Hua Yu,et al. Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells , 2004, Nature Medicine.