Medical Prognosis Generation from General Blood Test Results Using Knowledge-Based and Machine-Learning-Based Approaches

In this paper, we present two approaches to generate prognosis from general blood test results. The first approach is a knowledge-based approach using ripple-down rules (RDR). The knowledge-based approach with RDR converts knowledge of pathologists into a knowledge base with the minimum intervention of knowledge engineers. The second approach is a machine-learning(ML)-based approach using decision tree, random forest and deep neural network (DNN). The ML-based approach learns patterns of attributes from various cases of general blood test. Our experimental results show that there are indeed some important patterns of the attributes in general blood test results, and they are adequately encoded by the both approaches.

[1]  Lior Rokach,et al.  Data Mining with Decision Trees - Theory and Applications , 2007, Series in Machine Perception and Artificial Intelligence.

[2]  Samir El-Masri,et al.  A survey of agent-based intelligent decision support systems to support clinical management and research , 2005, AAMAS 2005.

[3]  Eta S. Berner,et al.  Clinical Decision Support Systems , 1999, Health Informatics.

[4]  Sunita Sarawagi,et al.  Discriminative Methods for Multi-labeled Classification , 2004, PAKDD.

[5]  Dhiya Al-Jumeily,et al.  Toward an optimal use of artificial intelligence techniques within a clinical decision support system , 2015, 2015 Science and Information Conference (SAI).

[6]  Byeong Ho Kang,et al.  Multiple Classification Ripple Down Rules : Evaluation and Possibilities , 2000 .

[7]  A E Smith,et al.  Implementation of intelligent decision support systems in health care. , 2002, Journal of management in medicine.

[8]  Daniel B Hier,et al.  Clinical Decision Support Systems: An Effective Pathway to Reduce Medical Errors and Improve Patient Safety , 2010 .

[9]  Zhibin Jiang,et al.  A Knowledge-Based Variance Management System for Supporting the Implementation of Clinical Pathways , 2009, 2009 International Conference on Management and Service Science.

[10]  Brian R. Gaines,et al.  Induction of ripple-down rules applied to modeling large databases , 1995, Journal of Intelligent Information Systems.

[11]  Marcus Lieberman,et al.  Computer-Aided Diagnoses of Chronic Head Pain: Explanation, Study Data, Implications, and Challenges , 2006, Cranio : the journal of craniomandibular practice.

[12]  R. Malor,et al.  Ripple down rules: possibilities and limitations , 2010 .