Acute effects of black carbon and PM₂.₅ on children asthma admissions: a time-series study in a Chinese city.

Epidemiologic evidence for an association between black carbon (BC) and health outcomes is limited. We estimated associations and exposure-response relationships between childhood asthma admission and concentration of BC and PM2.5 (particle less than 2.5mm in aerodynamic diameter) in ambient air in Shanghai using a lag distributed model. The PM2.5 and the BC were significantly associated with childhood asthma admissions in single-pollution model. However, the effects of BC on asthma attacks were slightly stronger than those of PM2.5 after adjusting or not adjusting for NO2 and SO2. In conclusion, our study suggests combustion-associated particles are important in China. Black carbon should be considered as one of the air quality indicators in China.

[1]  A. Gasparrini,et al.  The short-term influence of temperature on daily mortality in the temperate climate of Montreal, Canada. , 2011, Environmental research.

[2]  Daniel Krewski,et al.  Public health benefits of strategies to reduce greenhouse-gas emissions: health implications of short-lived greenhouse pollutants , 2009, The Lancet.

[3]  Who Europe Air Quality Guidelines Global Update 2005: Particulate Matter, ozone, nitrogen dioxide and sulfur dioxide , 2006 .

[4]  S L Zeger,et al.  The National Morbidity, Mortality, and Air Pollution Study. Part I: Methods and methodologic issues. , 2000, Research report.

[5]  Richard L. Verrier,et al.  Association of Air Pollution with Increased Incidence of Ventricular Tachyarrhythmias Recorded by Implanted Cardioverter Defibrillators , 2005, Environmental health perspectives.

[6]  F. Dominici,et al.  Time-series studies of particulate matter. , 2004, Annual review of public health.

[7]  J. Chow,et al.  Comparison of Continuous and Filter-Based Carbon Measurements at the Fresno Supersite , 2006, Journal of the Air & Waste Management Association.

[8]  Antonio Gasparrini,et al.  Distributed Lag Linear and Non-Linear Models in R: The Package dlnm. , 2011, Journal of statistical software.

[9]  G. Mancini Clarion call for trials assessing "cardiopulmonary" agents to reduce morbidity and mortality in inflammatory lung diseases. , 2007, Chest.

[10]  P. Mulawa,et al.  P API reference , 2003 .

[11]  J. Schwartz,et al.  Air Pollution and ST-Segment Depression in Elderly Subjects , 2005, Environmental health perspectives.

[12]  B. Brunekreef,et al.  Air pollution and health , 2002, The Lancet.

[13]  M. Lippmann,et al.  Associations between Health Effects and Particulate Matter and Black Carbon in Subjects with Respiratory Disease , 2005, Environmental health perspectives.

[14]  C. Sioutas,et al.  Circulating Biomarkers of Inflammation, Antioxidant Activity, and Platelet Activation Are Associated with Primary Combustion Aerosols in Subjects with Coronary Artery Disease , 2008, Environmental health perspectives.

[15]  H. R. Anderson,et al.  Black Carbon as an Additional Indicator of the Adverse Health Effects of Airborne Particles Compared with PM10 and PM2.5 , 2011, Environmental health perspectives.

[16]  H. Sørensen,et al.  Gender differences in hospitalization rates for respiratory tract infections in Danish youth , 2004, Scandinavian journal of infectious diseases.

[17]  A Opperhuizen,et al.  Traffic-Related Air Pollution Affects Peak Expiratory Flow, Exhaled Nitric Oxide, and Inflammatory Nasal Markers , 2001, Archives of environmental health.

[18]  C. Bjornson,et al.  Gender differences in asthma in childhood and adolescence. , 2000, The journal of gender-specific medicine : JGSM : the official journal of the Partnership for Women's Health at Columbia.

[19]  Y. Lau,et al.  Association between air pollution and asthma admission among children in Hong Kong , 2006, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[20]  M. Kleinman,et al.  Personal and Ambient Air Pollution is Associated with Increased Exhaled Nitric Oxide in Children with Asthma , 2006, Environmental health perspectives.

[21]  S L Zeger,et al.  Exposure measurement error in time-series studies of air pollution: concepts and consequences. , 2000, Environmental health perspectives.

[22]  H. Kan,et al.  A time-stratified case-crossover study of fine particulate matter air pollution and mortality in Guangzhou, China , 2012, International Archives of Occupational and Environmental Health.

[23]  H. Schulz,et al.  Role of oxidative stress in ultrafine particle-induced exacerbation of allergic lung inflammation. , 2009, American journal of respiratory and critical care medicine.

[24]  J. V. van Amsterdam,et al.  Association between exhaled nitric oxide, ambient air pollution and respiratory health in school children , 2002, International archives of occupational and environmental health.

[25]  H. Kan,et al.  Associations between fine particle, coarse particle, black carbon and hospital visits in a Chinese city. , 2013, The Science of the total environment.

[26]  Alexandros Gryparis,et al.  Association between Traffic-Related Black Carbon Exposure and Lung Function among Urban Women , 2008, Environmental health perspectives.

[27]  A Gasparrini,et al.  Distributed lag non-linear models , 2010, Statistics in medicine.

[28]  Thomas Lumley,et al.  Exhaled Nitric Oxide in Children with Asthma and Short-Term PM2.5 Exposure in Seattle , 2005, Environmental health perspectives.

[29]  Joel Schwartz,et al.  Air pollution and child respiratory health: a case-crossover study in Australia and New Zealand. , 2005, American journal of respiratory and critical care medicine.

[30]  D. Dockery,et al.  Health Effects of Fine Particulate Air Pollution: Lines that Connect , 2006, Journal of the Air & Waste Management Association.

[31]  L. Wallace,et al.  Indoor particles: a review. , 1996, Journal of the Air & Waste Management Association.

[32]  Xiaohui Xu,et al.  Differentiating the associations of black carbon and fine particle with daily mortality in a Chinese city. , 2013, Environmental research.

[33]  Kazuhiko Ito,et al.  Time-Series Analysis of Mortality Effects of Fine Particulate Matter Components in Detroit and Seattle , 2010, Environmental health perspectives.

[34]  J. Schwartz,et al.  DIABETES ENHANCES VULNERABILITY TO PARTICULATE AIR POLLUTION-ASSOCIATED IMPAIRMENT IN VASCULAR REACTIVITY AND ENDOTHELIAL FUNCTION , 2004, Circulation.

[35]  Michael Q. Wang,et al.  Black carbon emissions in China , 2001 .

[36]  Tong Zhu,et al.  Acute Respiratory Inflammation in Children and Black Carbon in Ambient Air before and during the 2008 Beijing Olympics , 2011, Environmental health perspectives.

[37]  J Schwartz,et al.  The distributed lag between air pollution and daily deaths. , 2000, Epidemiology.

[38]  J Schwartz,et al.  Traffic related pollution and heart rate variability in a panel of elderly subjects , 2005, Thorax.

[39]  Particulate matter, sulfur dioxide, and daily mortality in Chongqing, China. , 2003 .

[40]  Panagiotis T Nastos,et al.  Outdoor particulate matter and childhood asthma admissions in Athens, Greece: a time-series study , 2010, Environmental health : a global access science source.

[41]  Haidong Kan,et al.  Differentiating the effects of fine and coarse particles on daily mortality in Shanghai, China. , 2007, Environment international.

[42]  P. Quincey A relationship between Black Smoke Index and Black Carbon concentration , 2007 .

[43]  L. Murr,et al.  Cytotoxic Responses and Potential Respiratory Health Effects of Carbon and Carbonaceous Nanoparticulates in the Paso del Norte Airshed Environment , 2008, International journal of environmental research and public health.

[44]  Xiaohui Xu,et al.  Fine particulate air pollution and daily mortality in Shenyang, China. , 2011, The Science of the total environment.