Enhancing Transferability of Features from Pretrained Deep Neural Networks for Lung Nodule Classification

Among most popular feature extractors, pretrained deep neural networks play a central role in transfer learning to extract high-level feature on small datasets. The transferable performance, however, cannot be guaranteed for the task of interest. To enhance the transferability, this paper employs fine-tuning and feature selection in a different way to improve the accuracy of lung nodule classification. The fine-tuning technique retrains the neural network using lung nodule dataset, while feature selection captures a useful subset of features for lung nodule classification. Preliminary experimental results on CT images from Lung Image Database Consortium and Image Database Resource Initiative (LIDC-IDRI) confirm that the classification accuracy on lung nodule can be significantly improved via finetuning and feature selection. Furthermore, the results outperform competitively handcrafted texture descriptors.

[1]  Michael S. Bernstein,et al.  ImageNet Large Scale Visual Recognition Challenge , 2014, International Journal of Computer Vision.

[2]  Jian Sun,et al.  Deep Residual Learning for Image Recognition , 2015, 2016 IEEE Conference on Computer Vision and Pattern Recognition (CVPR).

[3]  Gaël Varoquaux,et al.  Scikit-learn: Machine Learning in Python , 2011, J. Mach. Learn. Res..

[4]  Richard C. Pais,et al.  The Lung Image Database Consortium (LIDC) and Image Database Resource Initiative (IDRI): a completed reference database of lung nodules on CT scans. , 2011, Medical physics.

[5]  M. Roizen Reduced Lung-Cancer Mortality with Low-Dose Computed Tomographic Screening , 2012 .

[6]  Bill Triggs,et al.  Histograms of oriented gradients for human detection , 2005, 2005 IEEE Computer Society Conference on Computer Vision and Pattern Recognition (CVPR'05).

[7]  Wei Shen,et al.  Multi-scale Convolutional Neural Networks for Lung Nodule Classification , 2015, IPMI.

[8]  Leo Breiman,et al.  Random Forests , 2001, Machine Learning.

[9]  Matti Pietikäinen,et al.  Multiresolution Gray-Scale and Rotation Invariant Texture Classification with Local Binary Patterns , 2002, IEEE Trans. Pattern Anal. Mach. Intell..

[10]  Emmanuelle Gouillart,et al.  scikit-image: image processing in Python , 2014, PeerJ.

[11]  G. Saranya,et al.  Lung Nodule Classification Using Deep Features in Ct Images , 2016 .

[12]  Yoshua Bengio,et al.  How transferable are features in deep neural networks? , 2014, NIPS.

[13]  Stefan Carlsson,et al.  CNN Features Off-the-Shelf: An Astounding Baseline for Recognition , 2014, 2014 IEEE Conference on Computer Vision and Pattern Recognition Workshops.

[14]  Hong Zhao,et al.  A texture feature analysis for diagnosis of pulmonary nodules using LIDC-IDRI database , 2013, 2013 IEEE International Conference on Medical Imaging Physics and Engineering.

[15]  Dumitru Erhan,et al.  Going deeper with convolutions , 2014, 2015 IEEE Conference on Computer Vision and Pattern Recognition (CVPR).