Coffee consumption and bladder cancer risk

The relationship between coffee drinking and the risk of bladder cancer was analyzed within the framework of a French hospital‐based case‐control study conducted between 1984 and 1987, which included 690 cases of histologically confirmed bladder cancer (599 males and 91 females), and 690 age‐, sex‐ and hospital‐matched controls. To dissociate the effects of smoking and coffee drinking among males, the analysis of the male group was restricted to 2 contrasted subgroups: non‐smokers on the one hand, and current smokers and inhalers of black tobacco cigarettes on the other. Coffee drinking was found to be significantly associated with the risk of bladder cancer among men in both groups and the increase in the risk was dose‐dependent (OR = 1, 2.9, 5.1 respectively, for drinking 1, 2, × 3 cups of coffee per day among non‐smokers, and 1, 2.5 and 3.0 respectively, for drinking 1‐4, 5‐7, >7 cups among smokers). This result was not observed for women.

[1]  I. Berenblum,et al.  The effect of caffeine on two-stage skin carcinogenesis and on complete systemic carcinogenesis. , 1981, Carcinogenesis.

[2]  S. Mommsen,et al.  A case-control study of female bladder cancer. , 1983, European journal of cancer & clinical oncology.

[3]  D. Trichopoulos,et al.  Tobacco smoking, coffee drinking, and occupation as risk factors for bladder cancer in Greece. , 1985, Journal of the National Cancer Institute.

[4]  S. Yen,et al.  Coffee drinking and cancer of the lower urinary tract. , 1971, Journal of the National Cancer Institute.

[5]  P. Hartge,et al.  Coffee Drinking and Risk of Bladder Cancer , 1983 .

[6]  A. Miller,et al.  Tobacco use, occupation, coffee, various nutrients, and bladder cancer. , 1980, Journal of the National Cancer Institute.

[7]  D. West,et al.  Fluid intake and bladder cancer in UTAH , 1988, International journal of cancer.

[8]  A. Miller The etiology of bladder cancer from the epidemiological viewpoint. , 1977, Cancer research.

[9]  S. Walter,et al.  Coffee drinking and bladder cancer in Connecticut. , 1983, American journal of epidemiology.

[10]  A. Morrison,et al.  Coffee drinking and cancer of the lower urinary tract. , 1982, Journal of the National Cancer Institute.

[11]  E. Wynder,et al.  Bladder cancer in nonsmokers , 1986, Cancer.

[12]  R. Frentzel-Beyme,et al.  Life-style and occupational risk factors in cancer of the lower urinary tract. , 1986, American journal of epidemiology.

[13]  P. Vineis,et al.  Coffee drinking and bladder cancer. , 1988, Cancer letters.

[14]  D. Hémon,et al.  Tobacco and bladder cancer in males: Increased risk for inhalers and smokers of black tobacco , 1989, International journal of cancer.

[15]  C. González,et al.  Occupation, Tobacco Use, Coffee, and Bladder Cancer in the County of Mataro (Spain) , 1985, Cancer.

[16]  C. Mettlin,et al.  Dietary risk factors in human bladder cancer. , 1979, American journal of epidemiology.

[17]  J. Fraumeni,et al.  Coffee-drinking and bladder cancer. , 1971, Lancet.

[18]  R. Cartwright,et al.  The epidemiology of bladder cancer in West Yorkshire. A preliminary report on non-occupational aetiologies. , 1981, Carcinogenesis.

[19]  D. Louria,et al.  Life time occupation, smoking, caffeine, saccharine, hair dyes and bladder carcinogenesis. , 1982, International journal of epidemiology.

[20]  T. Sugimura,et al.  Mutagens in coffee and tea. , 1979, Mutation research.

[21]  J. Wahrendorf,et al.  The copenhagen case‐control study of bladder cancer. II. Effect of coffee and other beverages , 1986, International journal of cancer.

[22]  A. Miller,et al.  Dietary factors and the incidence of cancer of the urinary bladder. , 1988, American journal of epidemiology.

[23]  T. Nomura Timing of chemically induced neoplasia in mice revealed by the antineoplastic action of caffeine. , 1980, Cancer research.

[24]  W. Taylor,et al.  CARBENOXOLONE AND GASTRIC SECRETION , 1975, The Lancet.

[25]  D A Savitz,et al.  Estimating and correcting for confounder misclassification. , 1989, American journal of epidemiology.

[26]  N. Muñoz,et al.  Tobacco smoking, occupational exposure and bladder cancer in Argentina , 1987, International journal of cancer.