Role of ultrasound‐guided fine‐needle aspiration of indeterminate and suspicious axillary lymph nodes in the initial staging of breast carcinoma

Ultrasound (US) is more sensitive than physical examination alone in determining axillary lymph node involvement during preliminary staging of breast carcinoma. Due to occasional overlap of sonographic features of benign and indeterminate lymph nodes, fine‐needle aspiration (FNA) of sonographically indeterminate/suspicious lymph nodes can provide a more definitive diagnosis than US alone. This study was undertaken to determine the diagnostic accuracy of US‐guided FNA of indeterminate/suspicious/metastatic‐appearing axillary lymph nodes during the initial staging of breast carcinoma.

[1]  J L Picard,et al.  Axillary lymph node metastases in breast cancer: preoperative detection with US. , 1986, Radiology.

[2]  Umberto Veronesi,et al.  Sentinel-node biopsy to avoid axillary dissection in breast cancer with clinically negative lymph-nodes , 1997, The Lancet.

[3]  M. Pamilo,et al.  Real‐time ultrasound, axillary mammography, and clinical examination in the detection of axillary lymph node metastases in breast cancer patients. , 1989, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[4]  E. Mamounas.  Overview of National Surgical Adjuvant Breast Project neoadjuvant chemotherapy studies. , 1998, Seminars in oncology.

[5]  G. Bonadonna,et al.  Combined chemotherapy-radiotherapy approach in locally advanced (T3b-T4) breast cancer , 2004, Cancer Chemotherapy and Pharmacology.

[6]  Sacre Ra.  Clinical evaluation of axillar lymph nodes compared to surgical and pathological findings. , 1986 .

[7]  I. Vandewiele,et al.  Value of axillary ultrasonography and sonographically guided puncture of axillary nodes: A prospective study in 144 consecutive patients , 1997, Journal of clinical ultrasound : JCU.

[8]  Mamounas Ep.  Overview of National Surgical Adjuvant Breast Project neoadjuvant chemotherapy studies. , 1998 .

[9]  Theo Wiggers,et al.  Ultrasound-Guided Aspiration Biopsy for Detection of Nonpalpable Axillary Node Metastases in Breast Cancer Patients: New Diagnostic Method , 1997, World Journal of Surgery.

[10]  D. D. Hoff.  Phase I trials of dexrazoxane and other potential applications for the agent. , 1998 .

[11]  R Fábregas,et al.  Metastatic breast carcinoma in axillary lymph nodes: in vitro US detection. , 1997, Radiology.

[12]  E. Marussi,et al.  Accuracy of ultrasound and clinical examination in the diagnosis of axillary lymph node metastases in breast cancer. , 1991, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

[13]  O. Kosunen,et al.  Ultrasonographic detection of metastatic axillary lymph nodes in breast cancer. , 1990, Annales chirurgiae et gynaecologiae.

[14]  M. Lippman,et al.  Treatment of locally advanced breast cancer using primary induction chemotherapy with hormonal synchronization followed by radiation therapy with or without debulking surgery. , 1986, NCI monographs : a publication of the National Cancer Institute.

[15]  G. Royle,et al.  Ultrasound detection of axillary lymph node metastases in breast cancer. , 1989, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

[16]  A. Y. de Kanter,et al.  Multicentre study of ultrasonographically guided axillary node biopsy in patients with breast cancer , 1999, The British journal of surgery.

[17]  Mark C Kelley,et al.  Lymphatic mapping and sentinel lymphadenectomy for breast cancer. , 2004, American journal of surgery.

[18]  W. Yang,et al.  Detection of axillary lymph node metastases in breast carcinoma by technetium-99m sestamibi breast scintigraphy, ultrasound and conventional mammography , 1996, European Journal of Nuclear Medicine.