Lysosome-targeting chimaeras for degradation of extracellular proteins
暂无分享,去创建一个
Carolyn R. Bertozzi | C. Bertozzi | N. Riley | Nicholas M. Riley | S. Banik | Steven M. Banik | Kayvon Pedram | Simon Wisnovsky | Green Ahn | Kayvon Pedram | G. Ahn | S. Wisnovsky
[1] Jun S. Liu,et al. MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens , 2014, Genome Biology.
[2] G. Bu,et al. Apolipoprotein E as a Therapeutic Target in Alzheimer’s Disease: A Review of Basic Research and Clinical Evidence , 2016, CNS Drugs.
[3] R. Deshaies,et al. Protacs: Chimeric molecules that target proteins to the Skp1–Cullin–F box complex for ubiquitination and degradation , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[4] M. Prata,et al. A shortcut to the lysosome: the mannose-6-phosphate-independent pathway. , 2012, Molecular genetics and metabolism.
[5] W. Sly,et al. Enzyme therapy in mannose receptor-null mucopolysaccharidosis VII mice defines roles for the mannose 6-phosphate and mannose receptors , 2006, Proceedings of the National Academy of Sciences.
[6] Y. T. Wang,et al. Rapid and reversible knockdown of endogenous proteins by peptide-directed lysosomal degradation , 2014, Nature Neuroscience.
[7] Jamie B. Spangler,et al. Combination antibody treatment down-regulates epidermal growth factor receptor by inhibiting endosomal recycling , 2010, Proceedings of the National Academy of Sciences.
[8] Nicholas W. Kwiecien,et al. Improved Precursor Characterization for Data-Dependent Mass Spectrometry. , 2018, Analytical chemistry.
[9] Soumen Das,et al. Controlled Synthesis of End-Functionalized Mannose-6-phosphate Glycopolypeptides for Lysosome Targeting. , 2016, ACS macro letters.
[10] Melina Schuh,et al. A Method for the Acute and Rapid Degradation of Endogenous Proteins , 2017, Cell.
[11] J. Weissman,et al. Functional genomics platform for pooled screening and generation of mammalian genetic interaction maps , 2014, Nature Protocols.
[12] Anton Arkhipov,et al. EGFR oligomerization organizes kinase-active dimers into competent signalling platforms , 2016, Nature Communications.
[13] C. Bustamante,et al. Chemically tunable mucin chimeras assembled on living cells , 2015, Proceedings of the National Academy of Sciences.
[14] Marco Y. Hein,et al. Accurate Proteome-wide Label-free Quantification by Delayed Normalization and Maximal Peptide Ratio Extraction, Termed MaxLFQ * , 2014, Molecular & Cellular Proteomics.
[15] J. Blenis,et al. Activation of PI3K/Akt and MAPK pathways regulates Myc-mediated transcription by phosphorylating and promoting the degradation of Mad1 , 2008, Proceedings of the National Academy of Sciences.
[16] P. Olinga,et al. Albumin modified with mannose 6‐phosphate: A potential carrier for selective delivery of antifibrotic drugs to rat and human hepatic stellate cells , 1999, Hepatology.
[17] R. G. Anderson,et al. Folate receptors targeted to clathrin-coated pits cannot regulate vitamin uptake. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[18] Max A. Horlbeck,et al. Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation , 2016, eLife.
[19] Marco Y. Hein,et al. The Perseus computational platform for comprehensive analysis of (prote)omics data , 2016, Nature Methods.
[20] M. Rebelatto,et al. A Biparatopic HER2-Targeting Antibody-Drug Conjugate Induces Tumor Regression in Primary Models Refractory to or Ineligible for HER2-Targeted Therapy. , 2016, Cancer cell.
[21] James E. Bradner,et al. Phthalimide conjugation as a strategy for in vivo target protein degradation , 2015, Science.
[22] James E. Bradner,et al. The dTAG system for immediate and target-specific protein degradation , 2018, Nature Chemical Biology.
[23] E. Isacoff,et al. Molecular basis for multimerization in the activation of the epidermal growth factor receptor , 2016, eLife.
[24] M. Naito,et al. SNIPERs-Hijacking IAP activity to induce protein degradation. , 2019, Drug discovery today. Technologies.
[25] S. Kornfeld,et al. Mannose 6-phosphate receptors: new twists in the tale , 2003, Nature Reviews Molecular Cell Biology.
[26] Israel Steinfeld,et al. BMC Bioinformatics BioMed Central , 2008 .
[27] Y. Hathout,et al. The human secretome atlas initiative: implications in health and disease conditions. , 2013, Biochimica et biophysica acta.
[28] Margaret R. Heider,et al. Exorcising the Exocyst Complex , 2012, Traffic.
[29] Steven P Gygi,et al. Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry , 2007, Nature Methods.
[30] Dennis L. Buckley,et al. Selective Target Protein Degradation via Phthalimide Conjugation , 2015 .
[31] M. Gary‐Bobo,et al. Mannose 6-phosphate receptor targeting and its applications in human diseases. , 2007, Current medicinal chemistry.
[32] Valentin Jaumouillé,et al. The position of lysosomes within the cell determines their luminal pH , 2016, The Journal of cell biology.
[33] M. Wilchek,et al. Affinity cleavage of cell surface antibodies using the avidin-biotin system. , 1993, Journal of immunological methods.
[34] Jüergen Cox,et al. The MaxQuant computational platform for mass spectrometry-based shotgun proteomics , 2016, Nature Protocols.
[35] J. Montero,et al. A Flexible Route to Mannose 6-Phosphonate Functionalized Derivatives , 2002 .
[36] R D Klausner,et al. Exposure of K562 cells to anti-receptor monoclonal antibody OKT9 results in rapid redistribution and enhanced degradation of the transferrin receptor , 1986, The Journal of cell biology.
[37] D. Berkowitz,et al. Mono- and bivalent ligands bearing mannose 6-phosphate (M6P) surrogates: targeting the M6P/insulin-like growth factor II receptor. , 2004, Organic letters.
[38] M. Mann,et al. Andromeda: a peptide search engine integrated into the MaxQuant environment. , 2011, Journal of proteome research.
[39] J. Xia,et al. The role of EGF-EGFR signalling pathway in hepatocellular carcinoma inflammatory microenvironment , 2013, Journal of cellular and molecular medicine.
[40] Marcel Garcia,et al. Synthesis of new sulfonate and phosphonate derivatives for cation-independent mannose 6-phosphate receptor targeting. , 2008, Bioorganic & medicinal chemistry letters.
[41] S. Dawson,et al. CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity , 2017, Nature.
[42] J. Montero,et al. Synthesis and receptor binding affinity of carboxylate analogues of the mannose 6-phosphate recognition marker. , 2006, Bioorganic & medicinal chemistry.
[43] Qun Zhou,et al. Conjugation of Mannose 6-Phosphate-containing Oligosaccharides to Acid α-Glucosidase Improves the Clearance of Glycogen in Pompe Mice* , 2004, Journal of Biological Chemistry.
[44] P. Shang,et al. Transferrin receptor 1 in cancer: a new sight for cancer therapy. , 2018, American journal of cancer research.
[45] S. Kornfeld,et al. Engineering of GlcNAc-1-Phosphotransferase for Production of Highly Phosphorylated Lysosomal Enzymes for Enzyme Replacement Therapy , 2017, Molecular therapy. Methods & clinical development.
[46] G. von Heijne,et al. Tissue-based map of the human proteome , 2015, Science.
[47] T. Igawa,et al. Sweeping antibody as a novel therapeutic antibody modality capable of eliminating soluble antigens from circulation , 2016, Immunological reviews.