Prostaglandin inhibitors and suxamethonium-induced myalgia

Sir,—In their recent article in the British Journal of Anaesthesia, Dr Kahraman and his colleagues [1] did not quote our original work on the hypothesis that pretreatment with prostaglandin synthesis inhibitors might reduce the severity of suxamethoniuminduced myalgia. We demonstrated that use of lysine acetyl salicylate 13 mg kg" i.v. 3 min before the administration of suxamethonium reduced the incidence and intensity of suxamethonium-induced myalgia [2]. Similarly, Dr Kahraman and his colleagues showed that diclofenac (an inhibitor of prostaglandin synthesis) 70 mg i.m. in the gluteal muscle 20 min before operation significantly reduced the incidence and intensity of suxamethonium-induced myalgia [1].