Process Technology in Cellular and Tissue Engineering

Many potential new therapeutic procedures employ autologous or allogeneic cells after ex-vivo expansion or even controlled differentiation. In many cases the aim of ex-vivo cultivation is not only the expansion of cells but also the formation of tissue-like or even organotypic structures for partial or complete replacement of vital functions. Such cellular and tissue engineering applications pose major challenges for process engineering. Critical needs exist for the improvement of cell culture environment, reactor design, process automation and scale translation.

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