Decapping protein EDC4 regulates DNA repair and phenocopies BRCA1

[1]  Minoru Takata,et al.  Biallelic mutations in the ubiquitin ligase RFWD3 cause Fanconi anemia , 2017, The Journal of clinical investigation.

[2]  F. Storici,et al.  Rad52 Inverse Strand Exchange Drives RNA-Templated DNA Double-Strand Break Repair. , 2017, Molecular cell.

[3]  Lara E Sucheston-Campbell,et al.  Germline whole exome sequencing and large-scale replication identifies FANCM as a likely high grade serous ovarian cancer susceptibility gene , 2017, Oncotarget.

[4]  C. Lefebvre,et al.  Mutational Profile of Metastatic Breast Cancers: A Retrospective Analysis , 2016, PLoS medicine.

[5]  Ahmet Zehir,et al.  Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer. , 2016, The New England journal of medicine.

[6]  Hongtae Kim,et al.  Factors forming the BRCA1-A complex orchestrate BRCA1 recruitment to the sites of DNA damage. , 2016, Acta biochimica et biophysica Sinica.

[7]  S. Francia,et al.  DICER, DROSHA and DNA damage response RNAs are necessary for the secondary recruitment of DNA damage response factors , 2016, Journal of Cell Science.

[8]  M. Smolka,et al.  TOPBP1 takes RADical command in recombinational DNA repair , 2016, The Journal of cell biology.

[9]  J. Bartek,et al.  TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity , 2016, The Journal of cell biology.

[10]  Alan Ashworth,et al.  BRCAness revisited , 2016, Nature Reviews Cancer.

[11]  R. Gibbons,et al.  The Fanconi Anemia Pathway Maintains Genome Stability by Coordinating Replication and Transcription , 2015, Molecular cell.

[12]  I. V. Rosado,et al.  The Fanconi Anemia Pathway Protects Genome Integrity from R-loops , 2015, PLoS genetics.

[13]  James Y. Zou Analysis of protein-coding genetic variation in 60,706 humans , 2015, Nature.

[14]  Andrés Aguilera,et al.  R loops: new modulators of genome dynamics and function , 2015, Nature Reviews Genetics.

[15]  Eliseos J. Mucaki,et al.  FANCM c.5791C>T nonsense mutation (rs144567652) induces exon skipping, affects DNA repair activity and is a familial breast cancer risk factor. , 2015, Human molecular genetics.

[16]  Edward L. Huttlin,et al.  Quantitative Proteomic Atlas of Ubiquitination and Acetylation in the DNA Damage Response. , 2015, Molecular cell.

[17]  J. Surrallés,et al.  Fanconi anemia: a model disease for studies on human genetics and advanced therapeutics. , 2015, Current opinion in genetics & development.

[18]  A. Valencia,et al.  POLE and POLD1 mutations in 529 kindred with familial colorectal cancer and/or polyposis: review of reported cases and recommendations for genetic testing and surveillance , 2015, Genetics in Medicine.

[19]  G. von Heijne,et al.  Tissue-based map of the human proteome , 2015, Science.

[20]  P. Huertas,et al.  BRCA1 accelerates CtIP-mediated DNA-end resection. , 2014, Cell reports.

[21]  J. Joung,et al.  Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage , 2014, Genes & development.

[22]  A. Aguilera,et al.  BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2 , 2014, Nature.

[23]  Suresh Ramakrishna,et al.  Gene disruption by cell-penetrating peptide-mediated delivery of Cas9 protein and guide RNA , 2014, Genome research.

[24]  Le Cong,et al.  Multiplex Genome Engineering Using CRISPR/Cas Systems , 2013, Science.

[25]  Juliane C. Dohm,et al.  Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia , 2011, Nature.

[26]  S. Seal,et al.  Exploring the link between MORF4L1 and risk of breast cancer , 2011, Breast Cancer Research.

[27]  R. Greenberg,et al.  The BRCA1-RAP80 Complex Regulates DNA Repair Mechanism Utilization by Restricting End Resection* , 2011, The Journal of Biological Chemistry.

[28]  J. Surrallés,et al.  Chromosome fragility in patients with Fanconi anaemia: diagnostic implications and clinical impact , 2011, Journal of Medical Genetics.

[29]  J. Hoeijmakers DNA damage, aging, and cancer. , 2009, The New England journal of medicine.

[30]  J. Bartek,et al.  The DNA-damage response in human biology and disease , 2009, Nature.

[31]  A. Consiglio,et al.  Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells , 2009, Nature.

[32]  J. Lykke-Andersen,et al.  The control of mRNA decapping and P-body formation. , 2008, Molecular cell.

[33]  M. Jinek,et al.  The C-terminal region of Ge-1 presents conserved structural features required for P-body localization. , 2008, RNA.

[34]  B. A. Ballif,et al.  ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage , 2007, Science.

[35]  Stephen D Dertinger,et al.  In vitro micronucleus scoring by flow cytometry: Differential staining of micronuclei versus apoptotic and necrotic chromatin enhances assay reliability , 2006, Environmental and molecular mutagenesis.

[36]  J. Lykke-Andersen,et al.  Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping. , 2005, Molecular cell.

[37]  Alan Ashworth,et al.  Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy , 2005, Nature.

[38]  Thomas Helleday,et al.  Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase , 2005, Nature.

[39]  A. Auerbach Diagnosis of Fanconi Anemia by Diepoxybutane Analysis , 2003, Current protocols in human genetics.

[40]  D. Sgroi,et al.  BACH1, a Novel Helicase-like Protein, Interacts Directly with BRCA1 and Contributes to Its DNA Repair Function , 2001, Cell.

[41]  V. Yamazaki,et al.  A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage , 2000, Current Biology.

[42]  L. Thompson,et al.  XRCC3 promotes homology-directed repair of DNA damage in mammalian cells. , 1999, Genes & development.

[43]  G E Tomlinson,et al.  BRCA2 is required for ionizing radiation-induced assembly of Rad51 complex in vivo. , 1999, Cancer research.

[44]  Yonghong Xiao,et al.  Association of BRCA1 with Rad51 in Mitotic and Meiotic Cells , 1997, Cell.

[45]  R. Greenberg,et al.  Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes. , 2006, Genes & development.

[46]  M. F. Parry,et al.  A Retrospective Analysis , 1990 .