Pbx1 regulates self-renewal of long-term hematopoietic stem cells by maintaining their quiescence.
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[1] A. Iwama,et al. Cytokine Signaling, Lipid Raft Clustering, and HSC Hibernation , 2007, Annals of the New York Academy of Sciences.
[2] I. Weissman,et al. B-cell development fails in the absence of the Pbx1 proto-oncogene. , 2007, Blood.
[3] Shamit Soneji,et al. Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors. , 2007, Immunity.
[4] G. Sauvageau,et al. Zfx: At the Crossroads of Survival and Self-Renewal , 2007, Cell.
[5] Leonid A. Mirny,et al. Zfx Controls the Self-Renewal of Embryonic and Hematopoietic Stem Cells , 2007, Cell.
[6] S. Armstrong,et al. FoxOs Are Critical Mediators of Hematopoietic Stem Cell Resistance to Physiologic Oxidative Stress , 2007, Cell.
[7] A. Ciarrocchi,et al. Id1 restrains myeloid commitment, maintaining the self-renewal capacity of hematopoietic stem cells , 2007, Proceedings of the National Academy of Sciences.
[8] S. Karlsson,et al. Smad7 promotes self-renewal of hematopoietic stem cells. , 2006, Blood.
[9] David G Kent,et al. Hematopoietic stem cells proliferate until after birth and show a reversible phase-specific engraftment defect. , 2006, The Journal of clinical investigation.
[10] M. Clarke,et al. Hematopoietic stem cell self-renewal. , 2006, Current opinion in genetics & development.
[11] Roger R. Gomis,et al. C/EBPβ at the core of the TGFβ cytostatic response and its evasion in metastatic breast cancer cells , 2006 .
[12] A. Iwama,et al. Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells , 2006, The EMBO journal.
[13] Keisuke Ito,et al. Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells , 2006, Nature Medicine.
[14] L. Selleri,et al. Hox cofactors in vertebrate development. , 2006, Developmental biology.
[15] L. Bystrykh,et al. The Polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion. , 2006, Blood.
[16] Irving L. Weissman,et al. Global analysis of proliferation and cell cycle gene expression in the regulation of hematopoietic stem and progenitor cell fates , 2005, The Journal of experimental medicine.
[17] T. Okano,et al. p57Kip2 is expressed in quiescent mouse bone marrow side population cells. , 2005, Biochemical and biophysical research communications.
[18] Pablo Tamayo,et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[19] I. Weissman,et al. Differential Expression of Novel Potential Regulators in Hematopoietic Stem Cells , 2005, PLoS genetics.
[20] S. Morrison,et al. Supplemental Experimental Procedures , 2022 .
[21] M. Cleary,et al. A Pbx1-dependent genetic and transcriptional network regulates spleen ontogeny , 2005, Development.
[22] I. Weissman,et al. Cell intrinsic alterations underlie hematopoietic stem cell aging. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[23] A. Su,et al. Gene expression profile of murine long-term reconstituting vs. short-term reconstituting hematopoietic stem cells. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[24] N. Manley,et al. Abnormalities of caudal pharyngeal pouch development in Pbx1 knockout mice mimic loss of Hox3 paralogs. , 2004, Developmental biology.
[25] C. Shaw,et al. Molecular Signatures of Proliferation and Quiescence in Hematopoietic Stem Cells , 2004, PLoS biology.
[26] I. Graef,et al. A Field of Myocardial-Endocardial NFAT Signaling Underlies Heart Valve Morphogenesis , 2004, Cell.
[27] S. Tapscott,et al. Pbx marks genes for activation by MyoD indicating a role for a homeodomain protein in establishing myogenic potential. , 2004, Molecular cell.
[28] P. Mellon,et al. Activin regulation of the follicle-stimulating hormone beta-subunit gene involves Smads and the TALE homeodomain proteins Pbx1 and Prep1. , 2004, Molecular endocrinology.
[29] M. Cleary,et al. Pbx1 is essential for adrenal development and urogenital differentiation , 2003, Genesis.
[30] J. Krosl,et al. The competitive nature of HOXB4-transduced HSC is limited by PBX1: the generation of ultra-competitive stem cells retaining full differentiation potential. , 2003, Immunity.
[31] M. Cleary,et al. Pbx1 regulates nephrogenesis and ureteric branching in the developing kidney. , 2003, Developmental biology.
[32] M. Cleary,et al. Pbx1 inactivation disrupts pancreas development and in Ipf1-deficient mice promotes diabetes mellitus , 2002, Nature Genetics.
[33] S. Chanda,et al. Requirement for Pbx1 in skeletal patterning and programming chondrocyte proliferation and differentiation. , 2001, Development.
[34] I. Weissman,et al. The Hox cofactor and proto-oncogene Pbx1 is required for maintenance of definitive hematopoiesis in the fetal liver. , 2001, Blood.
[35] R. Hammer,et al. Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo. , 2001, Developmental biology.
[36] C. Li,et al. Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection. , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[37] Xiang-Jiao Yang,et al. Cell Signaling Switches HOX-PBX Complexes from Repressors to Activators of Transcription Mediated by Histone Deacetylases and Histone Acetyltransferases , 2000, Molecular and Cellular Biology.
[38] L. Freedman,et al. p21 is a transcriptional target of HOXA10 in differentiating myelomonocytic cells. , 2000, Genes & development.
[39] D. Scadden,et al. Hematopoietic stem cell quiescence maintained by p21cip1/waf1. , 2000, Science.
[40] I. Weissman,et al. Identification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow , 1997, Cell.
[41] M Aguet,et al. Inducible gene targeting in mice , 1995, Science.
[42] J. Massagué,et al. C/EBPbeta at the core of the TGFbeta cytostatic response and its evasion in metastatic breast cancer cells. , 2006, Cancer cell.
[43] J. Massagué,et al. Transforming growth factor (cid:1) -induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation , 2022 .