Molecular approaches to the detection and monitoring of chronic myeloid leukemia: theory and practice.
暂无分享,去创建一个
[1] H. Heimpel,et al. Interferon alfa versus chemotherapy for chronic myeloid leukemia: a meta-analysis of seven randomized trials: Chronic Myeloid Leukemia Trialists' Collaborative Group. , 1997, Journal of the National Cancer Institute.
[2] C Chastang,et al. Interferon alfa-2b combined with cytarabine versus interferon alone in chronic myelogenous leukemia. French Chronic Myeloid Leukemia Study Group. , 1997, The New England journal of medicine.
[3] J. Reilly,et al. BCR-ABL transcript with an e19a2 (c3a2) junction in classical chronic myeloid leukemia. , 1997, Blood.
[4] H. Heimpel,et al. Molecular response of CML patients treated with interferon‐α monitored by quantitative Southern blot analysis , 1997 .
[5] G. Meloni,et al. Neutrophilic-chronic myeloid leukemia: a distinct disease with a specific molecular marker (BCR/ABL with C3/A2 junction) , 1996, Blood.
[6] J. Melo,et al. p190 BCR-ABL mRNA is expressed at low levels in p210-positive chronic myeloid and acute lymphoblastic leukemias. , 1996, Blood.
[7] J. Goldman,et al. Kinetics of increasing BCR-ABL transcript numbers in chronic myeloid leukemia patients who relapse after bone marrow transplantation. , 1996, Blood.
[8] R. V. van Etten,et al. The cytostatic function of c‐Abl is controlled by multiple nuclear localization signals and requires the p53 and Rb tumor suppressor gene products. , 1996, The EMBO journal.
[9] G. Martinelli,et al. Consistent amounts of acute leukemia-associated P190BCR/ABL transcripts are expressed by chronic myelogenous leukemia patients at diagnosis. , 1996, Blood.
[10] J. Melo,et al. Lack of correlation between ABL‐BCR expression and response to interferon‐α in chronic myeloid leukaemia , 1996 .
[11] S. Knuutila,et al. Minimal residual disease after allogeneic bone marrow transplantation for chronic myeloid leukaemia: a metaphase‐FISH study , 1996, British journal of haematology.
[12] J. Cigudosa,et al. BCR‐ABL rearrangement and Variant’Philadelphia chromosome in de novo acute myelogenous leukaemia FAB subtype M1 , 1995, British journal of haematology.
[13] J. Reiffers,et al. Chronic myelocytic leukemia patients achieving complete cytogenetic conversion under interferon alpha therapy: minimal residual disease follow-up. , 1995, Leukemia.
[14] F. Ragione,et al. Involvement of the cyclin‐dependent kinase‐4 inhibitor (CDKN2) gene in the pathogenesis of lymphoid blast crisis of chronic myelogenous leukaemia , 1995, British journal of haematology.
[15] G. Huez,et al. Detection of major bcr-abl gene expression at a very low level in blood cells of some healthy individuals. , 1995, Blood.
[16] R. Bouabdallah,et al. Minor breakpoint cluster region (m‐BCR) positive chronic myeloid leukaemia with an acute lymphoblastic leukaemia onset: a case report , 1995, British journal of haematology.
[17] T. Lion,et al. Increase of bcr-abl chimeric mRNA expression in tumor cells of patients with chronic myeloid leukemia precedes disease progression. , 1995, Blood.
[18] H. Kantarjian,et al. The breakpoint cluster region site in patients with Philadelphia chromosome–positive chronic myelogenous leukemia. Clinical, laboratory, and prognostic correlations , 1995, Cancer.
[19] J. Goldman,et al. Variable numbers of BCR‐ABL transcripts persist in CML patients who achieve complete cytogenetic remission with interferon‐α , 1995, British journal of haematology.
[20] A Ferrant,et al. Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients. , 1995, Blood.
[21] W. El-Deiry,et al. BCR-ABL-mediated inhibition of apoptosis with delay of G2/M transition after DNA damage: a mechanism of resistance to multiple anticancer agents. , 1995, Blood.
[22] D. Delia,et al. Establishment and molecular characterization of a novel leukemic cell line with Philadelphia chromosome expressing p230 BCR/ABL fusion protein. , 1995, Cancer research.
[23] J. Radich,et al. Benign marrow progenitors are enriched in the CD34+/HLA-DRlo population but not in the CD34+/CD38lo population in chronic myeloid leukemia: an analysis using interphase fluorescence in situ hybridization. , 1995, Blood.
[24] S. Richards,et al. UK Medical Research Council randomised, multicentre trial of interferon-αn1 for chronic myeloid leukaemia: improved survival irrespective of cytogenetic response , 1995, The Lancet.
[25] D. Catovsky,et al. Molecular cytogenetics of chronic myeloid leukemia with atypical t(6;9) (p23;q34) translocation. , 1995, Leukemia.
[26] R. Bouabdallah,et al. Philadelphia chromosome‐negative chronic myeloid leukaemia: a report of 14 new cases , 1995, British journal of haematology.
[27] H. Kantarjian,et al. Quantification of the breakpoint cluster region rearrangement for clinical monitoring in Philadelphia chromosome-positive chronic myeloid leukemia. , 1995, Blood.
[28] J. Radich,et al. Polymerase chain reaction detection of the BCR-ABL fusion transcript after allogeneic marrow transplantation for chronic myeloid leukemia: results and implications in 346 patients. , 1995, Blood.
[29] K. Ishizaki,et al. Hemizygous expression of the wild‐type p53 allele may confer a selective growth advantage before complete inactivation of the p53 gene in the progression of chronic myelogenous leukaemia , 1995, British journal of haematology.
[30] J. Goldman,et al. Characterization of genomic BCR‐ABL breakpoints in chronic myeloid leukaemia by PCR , 1995, British journal of haematology.
[31] J. Goldman,et al. Homozygous deletions of the p16 tumor-suppressor gene are associated with lymphoid transformation of chronic myeloid leukemia. , 1995, Blood.
[32] N. Cross,et al. Quantitative PCR techniques and applications. , 1995, British journal of haematology.
[33] D. Campana,et al. Detection of minimal residual disease in acute leukemia: methodologic advances and clinical significance. , 1995, Blood.
[34] D. Ma,et al. Interferon response in chronic myeloid leukaemia correlates with ABL/BCR expression: a preliminary study , 1995, British journal of haematology.
[35] J. Halsey,et al. Analysis of molecular breakpoint and m‐RNA transcripts in a prospective randomized trial of interferon in chronic myeloid leukaemia: no correlation with clinical features, cytogenetic response, duration of chronic phase, or survival , 1995, British journal of haematology.
[36] H. Kantarjian,et al. Prolonged Survival in Chronic Myelogenous Leukemia after Cytogenetic Response to Interferon- Therapy , 1995, Annals of Internal Medicine.
[37] H. Kantarjian,et al. Philadelphia chromosome‐negative chronic myelogenous leukemia with rearrangement of the breakpoint cluster region. Long term follow‐up results , 1995, Cancer.
[38] H. Heimpel,et al. Randomized comparison of interferon-alpha with busulfan and hydroxyurea in chronic myelogenous leukemia. The German CML Study Group. , 1994, Blood.
[39] H. Kumagai,et al. Molecular elimination of Ph1 clone in a chronic myelogenous leukemia patient with interferon-alpha alone. , 1994, Leukemia.
[40] Z. Estrov,et al. Persistence of dormant leukemic progenitors during interferon-induced remission in chronic myelogenous leukemia. Analysis by polymerase chain reaction of individual colonies. , 1994, The Journal of clinical investigation.
[41] S. Iwata,et al. Heterogeneity of the breakpoint in the ABL gene in cases with BCR/ABL transcript lacking ABL exon a2. , 1994, Leukemia.
[42] J. Radich,et al. Detection of BCR-ABL fusion genes in adult acute lymphoblastic leukemia by the polymerase chain reaction. , 1994, Leukemia.
[43] J. Goldman,et al. Detection of residual leukaemia more than 10 years after allogeneic bone marrow transplantation for chronic myelogenous leukaemia. , 1994, Bone marrow transplantation.
[44] T. Lion. Clinical implications of qualitative and quantitative polymerase chain reaction analysis in the monitoring of patients with chronic myelogenous leukemia. The European Investigators on Chronic Myeloid Leukemia Group. , 1994, Bone marrow transplantation.
[45] M. Kirkland. ANTISENSE THERAPEUTICS IN HAEMATOLOGICAL MALIGNANCIES , 1994, British journal of haematology.
[46] J. Román,et al. Lymphoid blast crisis at the onset of chronic myelogenous leukaemia: molecular evidence , 1994, British journal of haematology.
[47] T. Fioretos,et al. No evidence for genomic imprinting of the human BCR gene. , 1994, Blood.
[48] C. Litz,et al. Paternal origin of the rearranged major breakpoint cluster region in chronic myeloid leukemia. , 1994, Blood.
[49] C. Litz,et al. Chronic myelogenous leukemia: molecular diagnostic considerations. , 1994, Human pathology.
[50] M. Taniwaki,et al. Prognostic significance of loss of a chromosome 17p and p53 gene mutations in blast crisis of chronic myelogenous leukaemia , 1994, British journal of haematology.
[51] J. Goldman,et al. Relapse of chronic myeloid leukemia after allogeneic bone marrow transplant: the case for giving donor leukocyte transfusions before the onset of hematologic relapse. , 1994, Blood.
[52] B. Clarkson,et al. A 62-kilodalton tyrosine phosphoprotein constitutively present in primary chronic phase chronic myelogenous leukemia enriched lineage negative blast populations. , 1994, Leukemia.
[53] H. Döhner,et al. Detection of chimeric BCR-ABL genes on bone marrow samples and blood smears in chronic myeloid and acute lymphoblastic leukemia by in situ hybridization. , 1994, Blood.
[54] X. H. Wang,et al. Variable transcription of BCR-ABL by Ph+ cells arising from hematopoietic progenitors in chronic myeloid leukemia. , 1994, Blood.
[55] H. Cavé,et al. Prospective monitoring and quantitation of residual blasts in childhood acute lymphoblastic leukemia by polymerase chain reaction study of delta and gamma T-cell receptor genes. , 1994, Blood.
[56] Sante Tura,et al. Interferon alfa-2a as compared with conventional chemotherapy for the treatment of chronic myeloid leukemia. , 1994, The New England journal of medicine.
[57] J. Goldman,et al. A comparison of the sensitivity of blood and bone marrow for the detection of minimal residual disease in chronic myeloid leukaemia , 1994, British journal of haematology.
[58] D. Green,et al. BCR-ABL Maintains Resistance of Chronic Myelogenous Leukemia Cells to Apoptotic Cell Death , 1994 .
[59] X. H. Wang,et al. Detection and direct sequence identification of BCR-ABL mRNA in Ph+ chronic myeloid leukemia. , 1993, Experimental hematology.
[60] K. Goi,et al. A novel 203 kD aberrant BCR‐ABL product in a girl with Philadelphia chromosome positive acute lymphoblastic leultaemia , 1993, British journal of haematology.
[61] F. Aversa,et al. Outcome for patients who relapse after allogeneic bone marrow transplantation for chronic myeloid leukemia. Chronic Leukemia Working Party. European Bone Marrow Transplantation Group , 1993 .
[62] G. Gahrton,et al. Bone marrow transplantation for chronic myeloid leukemia: long-term results. Chronic Leukemia Working Party of the European Group for Bone Marrow Transplantation. , 1993, Bone marrow transplantation.
[63] Nanxin Li,et al. BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein , 1993, Cell.
[64] A. Chase,et al. Competitive polymerase chain reaction to estimate the number of BCR-ABL transcripts in chronic myeloid leukemia patients after bone marrow transplantation. , 1993, Blood.
[65] A. Rimm,et al. 1993 progress report from the International Bone Marrow Transplant Registry. Advisory Committee of the International Bone Marrow Transplant Registry. , 1993, Bone marrow transplantation.
[66] B. Chapuis,et al. Adoptive immunotherapy for recurrent CML after BMT. , 1993, Bone marrow transplantation.
[67] Z. Estrov,et al. Chronic Myelogenous Leukemia : A Concise Update , 2003 .
[68] C. Bartram. Detection of minimal residual leukemia by the polymerase chain reaction: potential implications for therapy. , 1993, Clinica chimica acta; international journal of clinical chemistry.
[69] D. Ma,et al. Combined interferon alfa-2a and cytosine arabinoside as first-line treatment for chronic myeloid leukemia. , 1993, Acta haematologica.
[70] K. Akashi,et al. T lymphoid/myeloid bilineal crisis in chronic myelogenous leukemia. , 1993, Experimental hematology.
[71] M. Baccarani,et al. The type of BCR/ABL junction does not predict the survival of patients with Ph1‐positive chronic myeloid leukaemia , 1993, British journal of haematology.
[72] S. Sowerby,et al. DNA sequence analysis of the major breakpoint cluster region of the BCR gene rearranged in Philadelphia-positive human leukemias. , 1993, Oncogene.
[73] J. Melo,et al. Expression of the ABL-BCR fusion gene in Philadelphia-positive acute lymphoblastic leukemia. , 1993, Blood.
[74] P. Martiat,et al. Minimal residual disease after allogeneic bone marrow transplantation for chronic myeloid leukaemia in first chronic phase: correlations with acute graft‐versus‐host disease and relapse , 1993, British journal of haematology.
[75] D. Huhn,et al. Genetic alterations in the p53 gene in the blast crisis of chronic myelogenous leukemia: analysis by polymerase chain reaction based techniques. , 1993, Leukemia.
[76] R. Brunning,et al. Duplication of small segments within the major breakpoint cluster region in chronic myelogenous leukemia. , 1993, Blood.
[77] J. Rowley,et al. Cytogenetic clonality in myelodysplastic syndromes studied with fluorescence in situ hybridization: lineage, response to growth factor therapy, and clone expansion , 1993 .
[78] T. Lion,et al. Early detection of relapse after bone marrow transplantation in patients with chronic myelogenous leukaemia , 1993, The Lancet.
[79] C. Bloomfield,et al. Clinical significance of the BCR-ABL fusion gene in adult acute lymphoblastic leukemia: a Cancer and Leukemia Group B Study (8762). , 1992, Blood.
[80] J. Tanzer,et al. Quantitative determination of the hybrid Bcr‐Abl RNA in patients with chronic myelogenous leukaemia under interferon therapy , 1992, British journal of haematology.
[81] K. Ishizaki,et al. Frequent p53 gene mutations in blast crisis of chronic myelogenous leukemia, especially in myeloid crisis harboring loss of a chromosome 17p. , 1992, Cancer research.
[82] J. Tanzer,et al. Polymerase chain reaction detection of residual disease in chronic myeloid leukemia patients in complete cytogenetic remission under interferon with or without chemotherapy. , 1992, Leukemia.
[83] T. Lion,et al. Parental origin of chromosomes involved in the translocation t(9;22) , 1992, Nature.
[84] S. Seeber,et al. No correlation between the type of bcr-abl hybrid messenger RNA and platelet counts in chronic myelogenous leukemia [letter] , 1992 .
[85] C. Sawyers,et al. Dominant negative MYC blocks transformation by ABL oncogenes , 1992, Cell.
[86] C. Higano,et al. Use of alpha interferon for the treatment of relapse of chronic myelogenous leukemia in chronic phase after allogeneic bone marrow transplantation. , 1992, Blood.
[87] C. Westbrook,et al. The role of molecular techniques in the clinical management of leukemia: Lessons from the philadelphia chromosome , 1992, Cancer.
[88] S H Neoh,et al. Quantitation of targets for PCR by use of limiting dilution. , 1992, BioTechniques.
[89] S. Thibodeau,et al. Molecular remission occurring after donor leukocyte infusions for the treatment of relapsed chronic myelogenous leukemia after allogeneic bone marrow transplantation. , 1992, Bone marrow transplantation.
[90] A. Rimm,et al. Progress report from the International Bone Marrow Transplant Registry. , 1992, Bone marrow transplantation.
[91] B. Neel,et al. Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21 , 1992, Nature.
[92] M. Negrini,et al. A new chromosomal breakpoint in Ph positive, bcr negative chronic myelogenous leukemia. Report of a case. , 1992, Cancer genetics and cytogenetics.
[93] Y. Shaul,et al. c-abl has a sequence-specific enhancer binding activity , 1992, Cell.
[94] O. Witte,et al. Initiation of deregulated growth of multipotent progenitor cells by bcr-abl in vitro. , 1992, Science.
[95] J. Inazawa,et al. Absence in Ph-negative, M-BCR rearrangement-positive chronic myelogenous leukemia of linkage between 5' ABL and 3' M-BCR sequences in Philadelphia translocation. , 1992, Leukemia.
[96] P. Elvin,et al. Amplification and sequencing of genomic breakpoints located within the M-bcr region by Vectorette-mediated polymerase chain reaction. , 1992, Leukemia.
[97] M. Olson,et al. Metaphase and interphase cytogenetics with Alu-PCR-amplified yeast artificial chromosome clones containing the BCR gene and the protooncogenes c-raf-1, c-fms, and c-erbB-2. , 1992, Cancer research.
[98] R. Salgia,et al. Tyrosine phosphorylation of rasGAP and associated proteins in chronic myelogenous leukemia cell lines. , 1992, Blood.
[99] Jean Y. J. Wang,et al. Cell Cycle—Regulated Binding of c-Abl Tyrosine Kinase to DNA , 1992, Science.
[100] Emil,et al. Detection of minimal residual disease by polymerase chain reaction in Philadelphia chromosome-positive chronic myelogenous leukemia following interferon therapy. , 1992, Blood.
[101] T. Lints,et al. The hematopoietically expressed vav proto-oncogene shares homology with the dbl GDP-GTP exchange factor, the bcr gene and a yeast gene (CDC24) involved in cytoskeletal organization. , 1992, Oncogene.
[102] A. Barrett,et al. Donor leukocyte infusions for chronic myeloid leukemia in relapse after allogeneic bone marrow transplantation [letter] , 1992 .
[103] N. Kamada,et al. Molecular elimination of the minimal residual Ph1 clone with IFNα in CML , 1992, The Lancet.
[104] G. Daley,et al. Blast crisis in a murine model of chronic myelogenous leukemia. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[105] M. Bar‐eli,et al. Abnormalities of the retinoblastoma gene in the pathogenesis of acute leukemia , 1991 .
[106] P. Ely,et al. bcr/abl mRNA DETECTION FOLLOWING BONE MARROW TRANSPLANTATION FOR CHRONIC MYELOGENOUS LEUKEMIA , 1991, Transplantation.
[107] N. Kamada,et al. Molecular studies of chronic myelogenous leukemia using the polymerase chain reaction , 1991, Cancer.
[108] A. Gratwohl,et al. Second transplants for leukaemic relapse after bone marrow transplantation: high early mortality but favourable effect of chronic GVHD on continued remission. A REPORT BY THE EBMT LEUKAEMIA WORKING PARTY , 1991, British journal of haematology.
[109] J. Ritz,et al. Clinical significance of bcr-abl gene rearrangement detected by polymerase chain reaction after allogeneic bone marrow transplantation in chronic myelogenous leukemia. , 1991, Blood.
[110] E. Estey,et al. Significance of the P210 versus P190 molecular abnormalities in adults with Philadelphia chromosome-positive acute leukemia. , 1991, Blood.
[111] O. Witte,et al. The BCR gene encodes a novel serine/threonine kinase activity within a single exon , 1991, Cell.
[112] H. Saito,et al. Absence of the human retinoblastoma gene product in the megakaryoblastic crisis of chronic myelogenous leukemia. , 1991, Blood.
[113] K. Mills,et al. Mapping of breakpoints, and relationship to BCR-ABL RNA expression, in Philadelphia-chromosome-positive chronic myeloid leukaemia patients with a breakpoint around exon 14 (b3) of the BCR gene. , 1991, Leukemia.
[114] A. Rimm,et al. T-cell depletion of HLA-identical transplants in leukemia. , 1991, Blood.
[115] R. Espinosa,et al. axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase , 1991, Molecular and cellular biology.
[116] N. Rosenberg,et al. Differences in oncogenic potency but not target cell specificity distinguish the two forms of the BCR/ABL oncogene. , 1991, Molecular and cellular biology.
[117] K. Mills,et al. Does the breakpoint within the major breakpoint cluster region (M-bcr) influence the duration of the chronic phase in chronic myeloid leukemia? An analytical comparison of current literature. , 1991, Blood.
[118] N. Heisterkamp,et al. Entire ABL gene is joined with 5'-BCR in some patients with Philadelphia-positive leukemia. , 1991, Blood.
[119] B. Calabretta,et al. Selective inhibition of leukemia cell proliferation by BCR-ABL antisense oligodeoxynucleotides. , 1991, Science.
[120] P. Koduru,et al. Extramedullary blast crisis in chronic myelogenous leukemia. Demonstration of t‐cell lineage and philadelphia chromosome in a paraspinal tumor , 1991, Cancer.
[121] E. Bryant,et al. Chimeric BCR-abl messenger RNA as a marker for minimal residual disease in patients transplanted for Philadelphia chromosome-positive acute lymphoblastic leukemia. , 1991, Blood.
[122] O. Witte,et al. BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner , 1991, Cell.
[123] P. Martiat,et al. Philadelphia-negative (Ph-) chronic myeloid leukemia (CML): comparison with Ph+ CML and chronic myelomonocytic leukemia. The Groupe Français de Cytogénétique Hématologique. , 1991, Blood.
[124] A. Hagemeijer,et al. bcr-abl mRNA lacking abl exon a2 detected by polymerase chain reaction in a chronic myelogeneous leukemia patient. , 1991, Leukemia.
[125] J. Wang,et al. Detection of BCR-ABL proteins in blood cells of benign phase chronic myelogenous leukemia patients. , 1991, Cancer research.
[126] M. Bar‐eli,et al. The spectrum of molecular alterations in the evolution of chronic myelocytic leukemia. , 1991, The Journal of clinical investigation.
[127] P. Koduru,et al. Correlation between molecular and clinical events in the evolution of chronic myelocytic leukemia to blast crisis , 1991 .
[128] C. Hall,et al. Bcr encodes a GTPase-activating protein for p21rac , 1991, Nature.
[129] E. Thiel,et al. Detection of chimeric BCR-ABL genes in acute lymphoblastic leukaemia by the polymerase chain reaction , 1991, The Lancet.
[130] M. Slovak,et al. Persistence of bcr-able gene expression following bone marrow transplantation for chronic myelogenous leukemia in chronic phase. , 1991, Transplantation.
[131] O. Witte,et al. BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias , 1991, Molecular and cellular biology.
[132] R. Kurzrock,et al. Interferon-alpha produces sustained cytogenetic responses in chronic myelogenous leukemia. Philadelphia chromosome-positive patients. , 1991, Annals of internal medicine.
[133] J. Compton,et al. Nucleic acid sequence-based amplification , 1991, Nature.
[134] A. Morley,et al. Molecular diagnosis of Philadelphia negative CML using the polymerase chain reaction and DNA analysis: clinical features and course of M-bcr negative and M-bcr positive CML. , 1991, Leukemia.
[135] J. Wang,et al. Activation of tyrosinase kinase and microfilament-binding functions of c-abl by bcr sequences in bcr/abl fusion proteins , 1991, Molecular and cellular biology.
[136] J. Craig,et al. Philadelphia positive acute lymphoblastic leukemia in adults: age distribution, BCR breakpoint and prognostic significance. , 1991, Leukemia.
[137] J. Shuster,et al. Philadelphia chromosome and monosomy 7 in childhood acute lymphoblastic leukemia: a Pediatric Oncology Group study. , 1991, Blood.
[138] G. Morgan,et al. Detection of residual leukemia after bone marrow transplant for chronic myeloid leukemia: role of polymerase chain reaction in predicting relapse. , 1991, Blood.
[139] J. Fletcher,et al. Translocation (9;22) is associated with extremely poor prognosis in intensively treated children with acute lymphoblastic leukemia. , 1991, Blood.
[140] K. Suryanarayan,et al. Consistent involvement of the bcr gene by 9;22 breakpoints in pediatric acute leukemias. , 1991, Blood.
[141] W. Wilmanns,et al. Donor Leukocyte Transfusions for Treatment of Recurrent Chronic Myelogenous Leukemia in Marrow Transplant Patients , 1990 .
[142] D. Schaid,et al. The location of the Philadelphia chromosomal breakpoint site and prognosis in chronic granulocytic leukemia. , 1990, Leukemia.
[143] C. Mecucci,et al. P190 BCR/ABL transcript in a case of Philadelphia-positive multiple myeloma. , 1990, Leukemia.
[144] G. Saglio,et al. New type of Bcr/Abl junction in Philadelphia chromosome-positive chronic myelogenous leukemia. , 1990, Blood.
[145] N. Heisterkamp,et al. Ph-negative chronic myeloid leukemia: molecular analysis of ABL insertion into M-BCR on chromosome 22. , 1990, Blood.
[146] D Pinkel,et al. Detection of bcr-abl fusion in chronic myelogeneous leukemia by in situ hybridization , 1990, Science.
[147] G. Saglio,et al. Alternative BCR/ABL transcripts in chronic myeloid leukemia [letter; comment] , 1990 .
[148] G. Saglio,et al. Alternative BCR/ABL transcripts in chronic myeloid leukemia. , 1990, Blood.
[149] M. Gulley,et al. Bcr/abl recombinant DNA analysis versus karyotype in the diagnosis and therapeutic monitoring of chronic myeloid leukemia. , 1990, American journal of clinical pathology.
[150] Seamus J. Martin,et al. Induction of apoptosis (programmed cell death) in human leukemic HL-60 cells by inhibition of RNA or protein synthesis. , 1990, Journal of immunology.
[151] P. Martiat,et al. Use of pulsed field gel electrophoresis to characterize BCR gene involvement in CML patients lacking M-BCR rearrangement. , 1990, Leukemia.
[152] R. Foà,et al. ABL proteins in Philadelphia‐positive acute leukaemias and chronic myelogenous leukaemia blast crises , 1990, British journal of haematology.
[153] P. Martiat,et al. The role of alternative splicing patterns of BCR/ABL transcripts in the generation of the blast crisis of chronic myeloid leukaemia , 1990, British journal of haematology.
[154] Y. C. Chen,et al. Chromosome and bcr rearrangement in chronic myelogenous leukaemia and their correlation with clinical states and prognosis of the disease , 1990, British journal of haematology.
[155] F. Behm,et al. Philadelphia chromosome positive childhood acute lymphoblastic leukemia: clinical and cytogenetic characteristics and treatment outcome. A Pediatric Oncology Group study , 1990 .
[156] J. Sklar,et al. Expression of bcr-abl fusion transcripts following bone marrow transplantation for Philadelphia chromosome-positive leukemia. , 1990, Leukemia.
[157] P. Martiat,et al. Detection of residual BCR/ABL transcripts in chronic myeloid leukaemia patients in complete remission using the polymerase chain reaction and nested primers , 1990, British journal of haematology.
[158] J. Reiffers,et al. Long-term follow-up after bone marrow transplantation for chronic myelogenous leukemia: factors associated with relapse. , 1990, Bone marrow transplantation.
[159] A. Hagemeijer,et al. A novel variant of the bcr-abl fusion product in Philadelphia chromosome-positive acute lymphoblastic leukemia. , 1990, Leukemia.
[160] A. Keating,et al. Neutrophilic myelofibrosis presenting as philadelphia chromosome negative BCR non‐rearranged chronic myeloid leukemia , 1990, American journal of hematology.
[161] P. Martiat,et al. False-positive results with PCR to detect leukaemia-specific transcript , 1990, The Lancet.
[162] P. Martiat,et al. Interstitial insertion of varying amounts of ABL-containing genetic material into chromosome 22 in Ph-negative CML. , 1990, Leukemia.
[163] A. Elefanty,et al. bcr‐abl, the hallmark of chronic myeloid leukaemia in man, induces multiple haemopoietic neoplasms in mice. , 1990, The EMBO journal.
[164] J. Rowley,et al. Recurring chromosome abnormalities in leukemia and lymphoma. , 1990, Seminars in hematology.
[165] G. Jenster,et al. Acute leukaemia in bcr/abl transgenic mice , 1990, Nature.
[166] O. Witte,et al. Tyrosine kinase activity and transformation potency of bcr-abl oncogene products. , 1990, Science.
[167] G. Grosveld,et al. Chronic myeloid leukemia may be associated with several bcr-abl transcripts including the acute lymphoid leukemia-type 7 kb transcript. , 1990, Blood.
[168] J. Gabert,et al. Residual bcr/abl transcripts in chronic myeloid leukaemia , 1990, The Lancet.
[169] G. Daley,et al. Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome. , 1990, Science.
[170] M. Vidaud,et al. Frequent detection of minimal residual disease by use of the polymerase chain reaction in long-term survivors after bone marrow transplantation for chronic myeloid leukemia. , 1990, Leukemia.
[171] R. Berger,et al. Philadelphia-positive acute leukemia. Cytogenetic and molecular aspects. , 1990, Cancer genetics and cytogenetics.
[172] R. Kurzrock,et al. Philadelphia chromosome-negative chronic myelogenous leukemia without breakpoint cluster region rearrangement: a chronic myeloid leukemia with a distinct clinical course. , 1990, Blood.
[173] C. Sawyers,et al. Significance of residual leukaemia transcripts after bone marrow transplant for CML , 1990, The Lancet.
[174] L. Wiedemann,et al. Characterization of the translocation breakpoint sequences in philadelphia‐positive acute lymphoblastic leukemia , 1990, Genes, chromosomes & cancer.
[175] P. Martiat,et al. The position of the M‐BCR breakpoint does not predict the duration of chronic phase or survival in chronic myeloid leukaemia , 1990, British journal of haematology.
[176] K. Mills,et al. Further evidence that the site of the breakpoint in the major breakpoint cluster region (M-bcr) may be a prognostic indicator. , 1989, Leukemia.
[177] V. Rotter,et al. Rearrangements in the p53 gene in Philadelphia chromosome positive chronic myelogenous leukemia. , 1989, Blood.
[178] J. Gabert,et al. DETECTION OF RESIDUAL bcr/abl TRANSLOCATION BY POLYMERASE CHAIN REACTION IN CHRONIC MYELOID LEUKAEMIA PATIENTS AFTER BONE-MARROW TRANSPLANTATION , 1989, The Lancet.
[179] C. Marcelle,et al. Analysis of BCR‐ABL mRNA in chronic myelogenous leukemia patients and identification of a new BCR‐related sequence in human DNA , 1989, Genes, chromosomes & cancer.
[180] P. Gascón,et al. Fine mapping of chromosome 22 breakpoints within the breakpoint cluster region (bcr) implies a role for bcr exon 3 in determining disease duration in chronic myeloid leukemia. , 1989, American journal of human genetics.
[181] D. Baltimore,et al. The mouse type IV c-abl gene product is a nuclear protein, and activation of transforming ability is associated with cytoplasmic localization , 1989, Cell.
[182] C. Westbrook,et al. Detection of the Philadelphia chromosome in acute lymphoblastic leukemia by pulsed-field gel electrophoresis. , 1989, Blood.
[183] D. Ginsburg,et al. Detection of Philadelphia chromosome-positive cells by the polymerase chain reaction following bone marrow transplant for chronic myelogenous leukemia , 1989 .
[184] T. Soma,et al. No correlation between locations of bcr breakpoints and clinical states in Ph1-positive CML patients. , 1989, Leukemia.
[185] J. Rowley,et al. Unexpected heterogeneity of BCR-ABL fusion mRNA detected by polymerase chain reaction in Philadelphia chromosome-positive acute lymphoblastic leukemia. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[186] H. Kantarjian,et al. Detection of two alternative bcr/abl mRNA junctions and minimal residual disease in Philadelphia chromosome positive chronic myelogenous leukemia by polymerase chain reaction. , 1989, Blood.
[187] S. Kwok,et al. Avoiding false positives with PCR , 1989, Nature.
[188] J. Bosco,et al. Clinical stage of chronic granulocytic leukaemia and BCR breakpoint location in South‐East Asian patients , 1989, British journal of haematology.
[189] O. Witte,et al. Alternative forms of the BCR-ABL oncogene have quantitatively different potencies for stimulation of immature lymphoid cells , 1989, Molecular and cellular biology.
[190] W. Lange,et al. Detection by enzymatic amplification of bcr-abl mRNA in peripheral blood and bone marrow cells of patients with chronic myelogenous leukemia. , 1989, Blood.
[191] G. Morgan,et al. POLYMERASE CHAIN REACTION FOR DETECTION OF RESIDUAL LEUKAEMIA , 1989, The Lancet.
[192] S. Raimondi,et al. Comparative biochemical and cytogenetic studies of childhood acute lymphoblastic leukemia with the Philadelphia chromosome and other 22q 11 variants , 1989 .
[193] S. Thibodeau,et al. The bcr Gene in Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia , 1989 .
[194] S. Collins,et al. Rare occurrence of N-ras point mutations in Philadelphia chromosome positive chronic myeloid leukemia. , 1989, Blood.
[195] H. Kantarjian,et al. Ras oncogene mutations are rare late stage events in chronic myelogenous leukemia. , 1989, Blood.
[196] E. Thomas,et al. Indications for marrow transplantation in chronic myelogenous leukemia. , 1989, Blood.
[197] A. Hagemeijer,et al. Cytogenetic and molecular analysis in Philadelphia negative CML. , 1989, Blood.
[198] D. Baltimore,et al. N‐terminal mutations activate the leukemogenic potential of the myristoylated form of c‐abl. , 1989, The EMBO journal.
[199] R. Berger,et al. Ph1+bcr- acute leukemias: implication of Alu sequences in a chromosomal translocation occurring in the new cluster region within the BCR gene. , 1989, Oncogene.
[200] N. Heisterkamp,et al. Nucleotide sequence of both reciprocal translocation junction regions in a patient with Ph positive acute lymphoblastic leukaemia, with a breakpoint within the first intron of the BCR gene. , 1989, Nucleic acids research.
[201] J. Wang,et al. Deletion of an N‐terminal regulatory domain of the c‐abl tyrosine kinase activates its oncogenic potential. , 1989, The EMBO journal.
[202] K. Sullivan,et al. HLA-identical marrow transplantation during accelerated-phase chronic myelogenous leukemia: analysis of survival and remission duration. , 1988, Blood.
[203] J. Goldman,et al. Rearrangement of the Breakpoint Cluster Region and Expression of P210 BCR-ABL in a "Masked" Philadelphia Chromosome-Positive Acute Myeloid Leukemia , 1988 .
[204] D. Przepiorka. Breakpoint zone of bcr in chronic myelogenous leukemia does not correlate with disease phase or prognosis. , 1988, Cancer genetics and cytogenetics.
[205] T. Pawson,et al. Non-catalytic domains of cytoplasmic protein-tyrosine kinases: regulatory elements in signal transduction. , 1988, Oncogene.
[206] R. Kurzrock,et al. Significance and correlations of molecular analysis results in patients with Philadelphia chromosome-negative chronic myelogenous leukemia and chronic myelomonocytic leukemia. , 1988, The American journal of medicine.
[207] J U Gutterman,et al. The molecular genetics of Philadelphia chromosome-positive leukemias. , 1988, The New England journal of medicine.
[208] G. Saglio,et al. Variability of the molecular defects corresponding to the presence of a Philadelphia chromosome in human hematologic malignancies. , 1988, Blood.
[209] R. Chaganti,et al. Clinical evaluation of a DNA probe assay for the Philadelphia (Ph1) translocation in chronic myelogenous leukemia. , 1988, Leukemia.
[210] R. Kurzrock,et al. Philadelphia-negative chronic myelogenous leukemia with breakpoint cluster region rearrangement: molecular analysis, clinical characteristics, and response to therapy. , 1988, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[211] R. Silver,et al. The location of breakpoints within the breakpoint cluster region (bcr) of chromosome 22 in chronic myeloid leukemia. , 1988, Leukemia.
[212] O. Witte,et al. Selective transformation of primitive lymphoid cells by the BCR/ABL oncogene expressed in long-term lymphoid or myeloid cultures , 1988, Molecular and cellular biology.
[213] K. Mills,et al. The site of the breakpoint within the bcr is a prognostic factor in Philadelphia-positive CML patients. , 1988, Blood.
[214] K. Ohyashiki,et al. Analysis of DNA from cells fixed in Carnoy's solution for cytogenetic study. , 1988, Cancer genetics and cytogenetics.
[215] H. Kantarjian,et al. Detection of minimal residual bcr/abl transcripts by a modified polymerase chain reaction. , 1988, Blood.
[216] R. Kurzrock,et al. Analysis of breakpoints within the bcr gene and their correlation with the clinical course of Philadelphia-positive chronic myelogenous leukemia. , 1988, Blood.
[217] E. Coustan-Smith,et al. Variable Philadelphia breakpoints and potential lineage restriction of bcr rearrangement in acute lymphoblastic leukemia , 1988 .
[218] R. Hoffmann,et al. Bone marrow transplantation for chronic myelogenous leukemia in chronic phase. Increased risk for relapse associated with T-cell depletion. , 1988 .
[219] W. Gregory,et al. Bone marrow transplantation for chronic myeloid leukaemia in first chronic phase: importance of a graft‐versus‐leukaemia effect , 1988, British journal of haematology.
[220] J. Goldman,et al. Cytogenetic events after bone marrow transplantation for chronic myeloid leukemia in chronic phase. , 1988, Blood.
[221] S. Smith,et al. Heterogeneity of genomic fusion of BCR and ABL in Philadelphia chromosome-positive acute lymphoblastic leukemia. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[222] R. Kriz,et al. Sequence similarity of phospholipase C with the non-catalytic region of src , 1988, Nature.
[223] R. Gale,et al. Molecular abnormalities of bcr and c-abl in chronic myelogenous leukemia associated with a long chronic phase. , 1988, Blood.
[224] G. Dewald,et al. Possible cytogenetic distinction between lymphoid and myeloid blast crisis in chronic granulocytic leukemia , 1988, American journal of hematology.
[225] B. Hjelle,et al. Transforming genes in chronic myelogenous leukemia. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[226] M. L. Le Beau,et al. Long-range mapping of the Philadelphia chromosome by pulsed-field gel electrophoresis. , 1988, Blood.
[227] D. Bevan,et al. The correlation of breakpoint cluster region rearrangement and p210 phl/abl expression with morphological analysis of Ph-negative chronic myeloid leukemia and other myeloproliferative diseases. , 1988, Blood.
[228] Goldie Jh,et al. Impact of dose-intense chemotherapy on the development of permanent drug resistance. , 1987 .
[229] N. Heisterkamp,et al. The BCR/ABL hybrid gene. , 1987, Bailliere's clinical haematology.
[230] J. Wainscoat,et al. Molecular diagnosis of haematological disorders using DNA from stored bone marrow slides , 1987, British journal of haematology.
[231] R. Kurzrock,et al. Expression of c-abl in Philadelphia-positive acute myelogenous leukemia. , 1987, Blood.
[232] G. Torelli,et al. Philadelphia-positive chronic myeloid leukemia with a chromosome 22 breakpoint outside the breakpoint cluster region. , 1987, Blood.
[233] F. Behm,et al. Clinical and biologic hallmarks of the Philadelphia chromosome in childhood acute lymphoblastic leukemia. , 1987, Blood.
[234] A. Hagenbeek,et al. Nonhomogeneous distribution of leukemia in the bone marrow during minimal residual disease. , 1987, Blood.
[235] R. Kurzrock,et al. Molecular analysis of chromosome 22 breakpoints in adult Philadelphia‐positive acute lymphoblastic leukaemia , 1987, British journal of haematology.
[236] O. Witte,et al. In vitro transformation of immature hematopoietic cells by the P210 BCR/ABL oncogene product of the Philadelphia chromosome. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[237] J. Mears,et al. CML patients in blast crisis have breakpoints localized to a specific region of the BCR , 1987 .
[238] R. Kurzrock,et al. Molecular characteristics of chronic myelogenous leukemia in blast crisis. , 1987, Cancer genetics and cytogenetics.
[239] R. Gale,et al. DO ONCOGENES DETERMINE CLINICAL FEATURES IN CHRONIC MYELOID LEUKAEMIA? , 1987, The Lancet.
[240] M. Groudine,et al. Chronic myelogenous leukemia: amplification of a rearranged c-abl oncogene in both chronic phase and blast crisis. , 1987, Blood.
[241] H. Kantarjian,et al. Molecular analysis of interferon-induced suppression of Philadelphia chromosome in patients with chronic myeloid leukemia. , 1987, Blood.
[242] A. Berrebi,et al. bcr-abl RNA in patients with chronic myelogenous leukemia. , 1987, Blood.
[243] M. Greaves,et al. A novel abl protein expressed in Philadelphia chromosome positive acute lymphoblastic leukaemia positive acute lymphoblastic leukaemia , 1987, Nature.
[244] J. Bishop. The molecular genetics of cancer. , 1987, Science.
[245] I. Hariharan,et al. cDNA sequence for human bcr, the gene that translocates to the abl oncogene in chronic myeloid leukaemia. , 1987, The EMBO journal.
[246] R. Kurzrock,et al. Rearrangement in the breakpoint cluster region and the clinical course in Philadelphia-negative chronic myelogenous leukemia. , 1986, Annals of internal medicine.
[247] J. Mears,et al. Frequent and extensive deletion during the 9,22 translocation in CML. , 1986, Blood.
[248] Bruce A. Roe,et al. Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene , 1986, Cell.
[249] T. Ganesan,et al. Rearrangement of the bcr gene in Philadelphia-chromosome-negative chronic myeloid leukemia. , 1986, Haematology and blood transfusion.
[250] N. Heisterkamp,et al. Molecular analysis of both translocation products of a Philadelphia-positive CML patient. , 1986, Nucleic acids research.
[251] J. Gutterman,et al. Chronic myelogenous leukaemia: haematological remissions with alpha interferon , 1986, British journal of haematology.
[252] J W Gray,et al. Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[253] L. Kearney,et al. Correlation between chromosomal abnormalities and blast phenotype in the blast crisis of Ph-positive CGL. , 1986, Cancer genetics and cytogenetics.
[254] M. Olson,et al. Electrophoretic separations of large DNA molecules by periodic inversion of the electric field. , 1986, Science.
[255] A. Reeve,et al. Genomic diversity correlates with clinical variation in Ph′-negative chronic myeloid leukaemia , 1986, Nature.
[256] D. Patterson,et al. Fractionation of large mammalian DNA restriction fragments using vertical pulsed-field gradient gel electrophoresis , 1986, Somatic cell and molecular genetics.
[257] G. Daley,et al. Alternative 5′ exons in c-abl mRNA , 1986, Cell.
[258] H. Deeg,et al. Marrow transplantation for the treatment of chronic myelogenous leukemia. , 1986, Annals of internal medicine.
[259] R. Marcus,et al. Bone marrow transplantation for patients with chronic myeloid leukemia. , 1986, The New England journal of medicine.
[260] C. Bartram. Brief Definitive Report , 2022 .
[261] O. Witte,et al. Activation of the abl oncogene in murine and human leukemias. , 1985, Biochimica et biophysica acta.
[262] F. Mitelman,et al. Variant Ph translocations in chronic myeloid leukemia. , 1985, Cancer genetics and cytogenetics.
[263] A. Hagemeijer,et al. Translocation of c-abl to "masked" Ph in chronic myeloid leukemia. , 1985, Cancer genetics and cytogenetics.
[264] E. Canaani,et al. Fused transcript of abl and bcr genes in chronic myelogenous leukaemia , 1985, Nature.
[265] Kees Stam,et al. Structural organization of the bcr gene and its role in the Ph′ translocation , 1985, Nature.
[266] D. Golde,et al. Chronic myelogenous leukemia: recent advances. , 1985, Blood.
[267] D. Baltimore,et al. The minimum transforming region of v-abl is the segment encoding protein-tyrosine kinase , 1985, Journal of virology.
[268] R. Kurzrock,et al. The human cellular abl gene product in the chronic myelogenous leukemia cell line K562 has an associated tyrosine protein kinase activity. , 1985, Virology.
[269] R. Davis,et al. Activation of the c-abl oncogene by viral transduction or chromosomal translocation generates altered c-abl proteins with similar in vitro kinase properties , 1985, Molecular and cellular biology.
[270] J. Goldman,et al. GENOMIC ALTERATIONS INVOLVING THE C-MYC PROTO-ONCOGENE LOCUS DURING THE EVOLUTION OF A CASE OF CHRONIC GRANULOCYTIC LEUKAEMIA , 1984, The Lancet.
[271] D. Schwartz,et al. Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis , 1984, Cell.
[272] Francisco Cervantes,et al. Prognostic discrimination in "good-risk" chronic granulocytic leukemia , 1984 .
[273] M. L. Beau,et al. Deletion of 5q , 1984 .
[274] D. Arthur. Abnormalities of Chromosome 16 , 1984 .
[275] J. Stephenson,et al. Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22 , 1984, Cell.
[276] C. Bloomfield,et al. Chromosomal abnormalities and their clinical significance in acute lymphoblastic leukemia. Third International Workshop on Chromosomes in Leukemia. , 1983, Cancer research.
[277] J. Stephenson,et al. A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia , 1982, Nature.
[278] Goldman Jm,et al. New approaches in chronic granulocytic leukemia--origin, prognosis, and treatment. , 1982 .
[279] Koeffler Hp,et al. Chronic myelogenous leukemia--new concepts (first of two parts). , 1981 .
[280] W. N. Burnette,et al. "Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate--polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. , 1981, Analytical biochemistry.
[281] A. Sandberg. Second International Workshop on Chromosomes in Leukemia. , 1980, Cancer research.
[282] D. Baltimore,et al. A transformation-defective mutant of Abelson murine leukemia virus lacks protein kinase activity. , 1980, Proceedings of the National Academy of Sciences of the United States of America.
[283] H. Towbin,et al. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. , 1979, Proceedings of the National Academy of Sciences of the United States of America.
[284] D. Catovsky. Ph1‐POSITIVE ACUTE LEUKAEMIA AND CHRONIC GRANULOCYTIC LEUKAEMIA: ONE OR TWO DISEASES? , 1979, British journal of haematology.
[285] F. Reyes,et al. The Blast Crisis of Chronic Granulocytic Leukaemia: Megakaryoblastic Nature of Cells as Revealed by the Presence of Platelet‐Peroxidase—A Cytochemical Ultrastructural Study , 1978, British journal of haematology.
[286] G. Canellos,et al. Erythroblastic transformation of chronic granulocytic leukemia. , 1977, The American journal of medicine.
[287] G. Canellos,et al. Basophilic Chronic Granulocytic Leukaemia with Hyperhistaminaemia , 1977, British journal of haematology.
[288] B. Bain,et al. Megakaryoblastic transformation of chronic granulocytic leukaemia. An electron microscopy and cytochemial study. , 1977, Journal of clinical pathology.
[289] M. Greaves,et al. Blast Crisis of Chronic Myeloid Leukaemia (CML): I. PRESENTATION SIMULATING ACUTE LYMPHOID LEUKAEMIA (ALL) , 1976, British journal of haematology.
[290] G. Canellos,et al. Chronic granulocytic leukemia. , 1976, The Medical clinics of North America.
[291] E. Southern. Detection of specific sequences among DNA fragments separated by gel electrophoresis. , 1975, Journal of molecular biology.
[292] J. August,et al. Structural Proteins of Mammalian Oncogenic RNA Viruses: Multiple Antigenic Determinants of the Major Internal Protein and Envelope Glycoprotein , 1974, Journal of virology.
[293] J. Rowley. A New Consistent Chromosomal Abnormality in Chronic Myelogenous Leukaemia identified by Quinacrine Fluorescence and Giemsa Staining , 1973, Nature.
[294] J. Gart,et al. Cytogenetic studies in acute myelocytic leukemia with special emphasis on the occurrence of Ph1 chromosome. , 1970, Blood.
[295] C. Bloomfield,et al. Value of molecular monitoring during the treatment of chronic myeloid leukemia: a Cancer and Leukemia Group B study. , 1997, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[296] H. Kantarjian,et al. Significance of cytogenetic clonal evolution in chronic myelogenous leukemia. , 1996, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[297] S. Bi,et al. Retroviral transduction of Philadelphia-positive chronic myeloid leukemia cells with a human mutant p53 cDNA and its effect on in vitro proliferation. , 1994, Experimental hematology.
[298] J. Melo,et al. P190BCR-ABL chronic myeloid leukaemia: the missing link with chronic myelomonocytic leukaemia? , 1994, Leukemia.
[299] H. Heimpel,et al. New perspectives with interferon alpha. The German CML study group experience. , 1994, Bone marrow transplantation.
[300] J. Melo,et al. The ABL-BCR Fusion Gene Is Expressed in Chronic Myeloid Leukemia , 1993 .
[301] M. Campbell,et al. Acute lymphoid leukemia molecular phenotype in a patient with benign-phase chronic myelogenous leukemia. , 1993, Hematologic pathology.
[302] M. Rozman,et al. Prognosis of chronic myeloid leukemia: studies from the Barcelona Group. , 1993, Leukemia & lymphoma.
[303] F. Mitelman. The cytogenetic scenario of chronic myeloid leukemia. , 1993, Leukemia & lymphoma.
[304] H. Saito,et al. Long persistent bcr-abl positive transcript detected by polymerase chain reaction after marrow transplant for chronic myelogenous leukemia without clinical relapse: a study of 64 patients. , 1993, Blood.
[305] R. Berger. Differences between blastic chronic myeloid leukemia and Ph-positive acute leukemia. , 1993, Leukemia & lymphoma.
[306] M. Horowitz,et al. Second HLA-identical sibling transplants for leukemia recurrence. , 1992, Bone marrow transplantation.
[307] Sawyers Cl. The bcr-abl gene in chronic myelogenous leukaemia. , 1992 .
[308] R. Kurzrock,et al. Minimal residual disease in interferon-treated chronic myelogenous leukemia: results and pitfalls of analysis based on polymerase chain reaction. , 1992, Leukemia.
[309] D. Ginsburg,et al. Prognostic significance of Philadelphia chromosome-positive cells detected by the polymerase chain reaction after allogeneic bone marrow transplant for chronic myelogenous leukemia. , 1992, Blood.
[310] T. Yamada,et al. The relationship between the site of breakpoints within the bcr gene and thrombopoiesis of Philadelphia-positive chronic myelocytic leukemia. , 1991, Leukemia research.
[311] R. Kurzrock,et al. Appearance of acute leukemia-associated P190BCR-ABL in chronic myelogenous leukemia may correlate with disease progression. , 1991, Leukemia.
[312] I. Dubé,et al. Chromosome Abnormalities in Chronic Myeloid Leukaemia , 1990 .
[313] I. Dubé,et al. Chromosome abnormalities in chronic myeloid leukaemia. A model for acquired chromosome changes in haematological malignancy. , 1990, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.
[314] R. Gale,et al. Ph-chromosome positive acute leukemias and acute phase CML: one or two diseases? Two. , 1990, Leukemia research.
[315] P. Fenaux,et al. Detection of minimal residual disease in chronic myeloid leukemia patients after bone marrow transplantation by polymerase chain reaction. , 1990, Leukemia.
[316] C. Sawyers,et al. Molecular relapse in chronic myelogenous leukemia patients after bone marrow transplantation detected by polymerase chain reaction. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[317] J. Wiegant,et al. Detection of the Philadelphia chromosome in interphase nuclei. , 1990, Cytogenetics and cell genetics.
[318] M. Luppi,et al. Chronic myelogenous leukemia with typical clinical and morphological features can be Philadelphia chromosome negative and "bcr negative". , 1990, Hematologic pathology.
[319] B. Trask,et al. Analytical approaches to detection and characterization of disease-linked chromosome aberrations. , 1990, Bone marrow transplantation.
[320] R. Gale,et al. Do chromosome abnormalities determine the type of acute leukemia that develops in CML? , 1990, Leukemia.
[321] J. Trujillo,et al. Chromosomal breakpoints within the first intron of the ABL gene are nonrandom in patients with chronic myelogenous leukemia. , 1990, Blood.
[322] Larry J. Smith,et al. Rearrangement and expression of p53 in the chronic phase and blast crisis of chronic myelogenous leukemia. , 1990, Blood.
[323] C. Bartram,et al. Detection of minimal residual leukemia by polymerase chain reactions. , 1990, Bone marrow transplantation.
[324] R. Bernstein. Cytogenetics of chronic myelogenous leukemia. , 1988, Seminars in hematology.
[325] R. Storb,et al. Second marrow transplants in patients with leukemia who relapse after allogeneic marrow transplantation. , 1988, Bone marrow transplantation.
[326] C. Bartram. Rearrangement of the c-abl and bcr genes in Ph-negative CML and Ph-positive acute leukemias. , 1988, Leukemia.
[327] S. Smith,et al. A new fused transcript in Philadelphia chromosome positive acute lymphocytic leukaemia , 1987, Nature.
[328] Walker,et al. Chromosomal abnormalities identify high-risk and low-risk patients with acute lymphoblastic leukemia. , 1986, Blood.
[329] O. Witte,et al. The complexity of virus--cell interactions in Abelson virus infection of lymphoid and other hematopoietic cells. , 1985, Advances in immunology.
[330] M. Minamihisamatsu,et al. Chromosome 9 in variant Ph translocations. , 1985, Cancer genetics and cytogenetics.
[331] K B McCredie,et al. Philadelphia chromosome-positive adult acute leukemia with monosomy of chromosome number seven: a subgroup with poor response to therapy. , 1983, Leukemia research.
[332] E. Hook. Exclusion of chromosomal mosaicism: tables of 90%, 95% and 99% confidence limits and comments on use. , 1977, American journal of human genetics.
[333] P. Nowell,et al. A minute chromosome in human chronic granulocytic leukemia , 1960 .