NAP1L1‐MLLT10 is a rare recurrent translocation that is associated with HOXA activation and poor treatment response in T‐cell acute lymphoblastic leukaemia

expression, the testing threshold was extended to patients with HOXA9/ABL1 ≥ 0·4. Numbers in the relevant groups are indicated. Of the 173 HOXA High cases, 91 had known HOXA activating translocations, and 63 of the remaining 82 had material available for analysis. (D) Taqman Low-Density Array (TLDA) analysis of HOX gene transcription in NAP1L1-MLLT10 cases. Patient (Pt) samples show specific increases in HOXA gene expression relative to three normal thymic (Thy) controls, while other HOX loci were not activated.

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