Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury.

[1]  P. Doevendans,et al.  Myocardial Ischemia/Reperfusion Injury Is Mediated by Leukocytic Toll-Like Receptor-2 and Reduced by Systemic Administration of a Novel Anti–Toll-Like Receptor-2 Antibody , 2010, Circulation.

[2]  Tian Sheng Chen,et al.  Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs , 2009, Nucleic acids research.

[3]  Lianbo Yu,et al.  Detection of microRNA Expression in Human Peripheral Blood Microvesicles , 2008, PloS one.

[4]  P. Quesenberry,et al.  The Paradoxical Dynamism of Marrow Stem Cells: Considerations of Stem Cells, Niches, and Microvesicles , 2008, Stem Cell Reviews.

[5]  Cicek Gercel-Taylor,et al.  MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. , 2008, Gynecologic oncology.

[6]  P. Doevendans,et al.  Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium. , 2008, Stem cell research.

[7]  H. Northoff,et al.  Cardioprotection and cardiac regeneration by mesenchymal stem cells. , 2008, Panminerva medica.

[8]  Hui Zhao,et al.  Elucidating the Secretion Proteome of Human Embryonic Stem Cell-derived Mesenchymal Stem Cells*S , 2007, Molecular & Cellular Proteomics.

[9]  J. Lötvall,et al.  Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells , 2007, Nature Cell Biology.

[10]  D. Knight Editorial overview: cardioprotective drugs for myocardial ischemic injury--a therapeutic area at risk. , 2007, Current opinion in investigational drugs.

[11]  M. Salto‐Tellez,et al.  Derivation of Clinically Compliant MSCs from CD105+, CD24− Differentiated Human ESCs , 2007, Stem cells.

[12]  Sascha Keller,et al.  Exosomes: from biogenesis and secretion to biological function. , 2006, Immunology letters.

[13]  A. Caplan,et al.  Mesenchymal stem cells as trophic mediators , 2006, Journal of cellular biochemistry.

[14]  J Ratajczak,et al.  Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery , 2006, Leukemia.

[15]  J. Ingwall,et al.  Evidence supporting paracrine hypothesis for Akt‐modified mesenchymal stem cell‐mediated cardiac protection and functional improvement , 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[16]  Aled Clayton,et al.  Isolation and Characterization of Exosomes from Cell Culture Supernatants and Biological Fluids , 2006, Current protocols in cell biology.

[17]  J. Minguell,et al.  Mesenchymal Stem Cells and the Treatment of Cardiac Disease , 2006, Experimental biology and medicine.

[18]  Shiaw-Min Hwang,et al.  Cytokine interactions in mesenchymal stem cells from cord blood. , 2005, Cytokine.

[19]  J. Hare,et al.  Emerging role for bone marrow derived mesenchymal stem cells in myocardial regenerative therapy , 2005, Basic Research in Cardiology.

[20]  X. Qin,et al.  Paracrine action enhances the effects of autologous mesenchymal stem cell transplantation on vascular regeneration in rat model of myocardial infarction. , 2005, The Annals of thoracic surgery.

[21]  J. Ingwall,et al.  Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells , 2005, Nature Medicine.

[22]  G. Raposo,et al.  Exosomes: endosomal-derived vesicles shipping extracellular messages. , 2004, Current opinion in cell biology.

[23]  M. Pittenger,et al.  Mesenchymal stem cells and their potential as cardiac therapeutics. , 2004, Circulation research.

[24]  G. Bernardi,et al.  [Relationship of symptom-onset-to-balloon time and door-to-balloon time with mortality in patients undergoing angioplasty for acute myocardial infarction]. , 2000, Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology.

[25]  C M Gibson,et al.  Relationship of symptom-onset-to-balloon time and door-to-balloon time with mortality in patients undergoing angioplasty for acute myocardial infarction. , 2000, JAMA.

[26]  A. Saraste,et al.  Apoptosis in human acute myocardial infarction. , 1997, Circulation.

[27]  C. Melief,et al.  B lymphocytes secrete antigen-presenting vesicles , 1996, The Journal of experimental medicine.

[28]  R. Rosell,et al.  Circulating MicroRNA Signatures of Tumor-Derived Exosomes for Early Diagnosis of Non-Small-Cell Lung Cancer. , 2009, Clinical lung cancer.

[29]  M. Vidal,et al.  Proteomic analysis of secreted exosomes. , 2007, Sub-cellular biochemistry.

[30]  E. Bouhassira,et al.  Congenital Factor V Deficiency Low Plasma Levels of Tissue Factor Pathway Inhibitor in Patients With , 2006 .