Genome-wide DNA methylation analysis of peripheral blood cells derived from patients with first-episode schizophrenia in the Chinese Han population

[1]  Chad A. Cowan,et al.  Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants , 2020, Science.

[2]  T. Wojdacz,et al.  Current status of development of methylation biomarkers for in vitro diagnostic IVD applications , 2020, Clinical Epigenetics.

[3]  Yuan Wu,et al.  A Novel Schizophrenia Diagnostic Model Based on Statistically Significant Changes in Gene Methylation in Specific Brain Regions , 2020, BioMed research international.

[4]  Michael F. Green,et al.  Contributions of common genetic variants to risk of schizophrenia among individuals of African and Latino ancestry , 2019, Molecular Psychiatry.

[5]  J. Duan,et al.  From Schizophrenia Genetics to Disease Biology: Harnessing New Concepts and Technologies , 2019, Journal of psychiatry and brain science.

[6]  D. Bourc’his,et al.  The diverse roles of DNA methylation in mammalian development and disease , 2019, Nature Reviews Molecular Cell Biology.

[7]  R. Deng,et al.  LIMK1 and LIMK2 regulate cortical development through affecting neural progenitor cell proliferation and migration , 2019, Molecular Brain.

[8]  M. Maier,et al.  Impaired attentional modulation of sensorimotor control and cortical excitability in schizophrenia , 2019, Brain : a journal of neurology.

[9]  J. Mill,et al.  Guidance for DNA methylation studies: statistical insights from the Illumina EPIC array , 2019, BMC Genomics.

[10]  Damian Szklarczyk,et al.  STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets , 2018, Nucleic Acids Res..

[11]  Haniye Sadat Sajadi,et al.  Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 , 2018, Lancet.

[12]  Brielin C. Brown,et al.  Comparative genetic architectures of schizophrenia in East Asian and European populations , 2018, Nature Genetics.

[13]  H. C. Hartzell,et al.  Tropomodulin Isoform-Specific Regulation of Dendrite Development and Synapse Formation , 2018, The Journal of Neuroscience.

[14]  N. Girard,et al.  Epigenetic prediction of response to anti-PD-1 treatment in non-small-cell lung cancer: a multicentre, retrospective analysis. , 2018, The Lancet. Respiratory medicine.

[15]  E. Lo,et al.  Neuroglobin promotes neurogenesis through Wnt signaling pathway , 2018, Cell Death & Disease.

[16]  Jeffrey T Leek,et al.  Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis , 2018, Nature Neuroscience.

[17]  G. Kirov,et al.  Schizophrenia-associated genomic copy number variants and subcortical brain volumes in the UK Biobank , 2018, bioRxiv.

[18]  T M Hyde,et al.  GAD1 alternative transcripts and DNA methylation in human prefrontal cortex and hippocampus in brain development, schizophrenia , 2018, Molecular Psychiatry.

[19]  Chen Zhang,et al.  Interaction between BDNF and TNF-α genes in schizophrenia , 2018, Psychoneuroendocrinology.

[20]  D. Weinberger,et al.  Genetic insights into the neurodevelopmental origins of schizophrenia , 2017, Nature Reviews Neuroscience.

[21]  Qi Zhao,et al.  Circulating tumour DNA methylation markers for diagnosis and prognosis of hepatocellular carcinoma. , 2017, Nature materials.

[22]  Yuan Tian,et al.  ChAMP: updated methylation analysis pipeline for Illumina BeadChips , 2017, Bioinform..

[23]  T. Vos,et al.  Global, regional, and national incidence and prevalence, and years lived with disability for 328 diseases and injuries in 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016 , 2017 .

[24]  R. Chan,et al.  Whole-genome sequencing of monozygotic twins discordant for schizophrenia indicates multiple genetic risk factors for schizophrenia. , 2017, Journal of genetics and genomics = Yi chuan xue bao.

[25]  Eran Halperin,et al.  GLINT: a user‐friendly toolset for the analysis of high‐throughput DNA‐methylation array data , 2017, Bioinform..

[26]  Hui Peng,et al.  Pharmacological modulation of the voltage-gated neuronal Kv7/KCNQ/M-channel alters the intrinsic excitability and synaptic responses of pyramidal neurons in rat prefrontal cortex slices , 2017, Acta Pharmacologica Sinica.

[27]  A. Bird,et al.  The Role of Epigenetic Mechanisms in the Regulation of Gene Expression in the Nervous System , 2016, The Journal of Neuroscience.

[28]  Peter W. Laird,et al.  Comprehensive characterization, annotation and innovative use of Infinium DNA methylation BeadChip probes , 2016, Nucleic acids research.

[29]  Robin M. Murray,et al.  An integrated genetic-epigenetic analysis of schizophrenia: evidence for co-localization of genetic associations and differential DNA methylation , 2016, Genome Biology.

[30]  Daniel R Weinberger,et al.  Association of DNA Methylation Differences With Schizophrenia in an Epigenome-Wide Association Study. , 2016, JAMA psychiatry.

[31]  Eran Halperin,et al.  Sparse PCA corrects for cell type heterogeneity in epigenome-wide association studies , 2016, Nature Methods.

[32]  Jingyu Liu,et al.  Correspondence of DNA Methylation Between Blood and Brain Tissue and Its Application to Schizophrenia Research. , 2016, Schizophrenia bulletin.

[33]  G. Zunta-Soares,et al.  Interaction of BDNF with cytokines in chronic schizophrenia , 2016, Brain, Behavior, and Immunity.

[34]  P. Vourc'h,et al.  Roles of LIM kinases in central nervous system function and dysfunction , 2015, FEBS letters.

[35]  J. Corradi,et al.  Altered Expression of CDC42 Signaling Pathway Components in Cortical Layer 3 Pyramidal Cells in Schizophrenia , 2015, Biological Psychiatry.

[36]  Daniel R Weinberger,et al.  Mapping DNA methylation across development, genotype, and schizophrenia in the human frontal cortex , 2015, Nature Neuroscience.

[37]  Liang Niu,et al.  ENmix: a novel background correction method for Illumina HumanMethylation450 BeadChip , 2015, Nucleic acids research.

[38]  Peter L Molloy,et al.  De novo identification of differentially methylated regions in the human genome , 2015, Epigenetics & Chromatin.

[39]  M. Rietschel,et al.  Identification and functional characterization of rare SHANK2 variants in schizophrenia , 2015, Molecular Psychiatry.

[40]  C. Spencer,et al.  Biological Insights From 108 Schizophrenia-Associated Genetic Loci , 2014, Nature.

[41]  Martin J. Aryee,et al.  Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays , 2014, Bioinform..

[42]  Guimin Gao,et al.  Methylome-wide association study of schizophrenia: identifying blood biomarker signatures of environmental insults. , 2014, JAMA psychiatry.

[43]  K. Hansen,et al.  Functional normalization of 450k methylation array data improves replication in large cancer studies , 2014, Genome Biology.

[44]  Christofer L. Bäcklin,et al.  Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia , 2013, Genome Biology.

[45]  T. Dudev,et al.  Wnt and lithium: a common destiny in the therapy of nervous system pathologies? , 2013, Cellular and Molecular Life Sciences.

[46]  P. Laird,et al.  Low-level processing of Illumina Infinium DNA Methylation BeadArrays , 2013, Nucleic acids research.

[47]  Francesco Marabita,et al.  A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data , 2012, Bioinform..

[48]  Guangchuang Yu,et al.  clusterProfiler: an R package for comparing biological themes among gene clusters. , 2012, Omics : a journal of integrative biology.

[49]  S. Gong,et al.  Gene expression in accumbens GABA neurons from inbred rats with different drug‐taking behavior , 2011, Genes, brain, and behavior.

[50]  H. Hakonarson,et al.  ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data , 2010, Nucleic acids research.

[51]  Heike Wulff,et al.  Voltage-gated potassium channels as therapeutic targets , 2009, Nature Reviews Drug Discovery.

[52]  P. Shannon,et al.  Cytoscape: a software environment for integrated models of biomolecular interaction networks. , 2003, Genome research.

[53]  A. Bird,et al.  Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals , 2003, Nature Genetics.

[54]  T. Jentsch Neuronal KCNQ potassium channels:physislogy and role in disease , 2000, Nature Reviews Neuroscience.

[55]  Cheng Li,et al.  Adjusting batch effects in microarray expression data using empirical Bayes methods. , 2007, Biostatistics.