Activity-Dependent Presynaptic Facilitation and Hebbian LTP Are Both Required and Interact during Classical Conditioning in Aplysia

[1]  B. J. Winer.  Statistical Principles in Experimental Design , 1992 .

[2]  E. Kandel,et al.  Receptive fields and response properties of mechanoreceptor neurons innervating siphon skin and mantle shelf in Aplysia. , 1974, Journal of neurophysiology.

[3]  E. Kandel,et al.  Cellular studies of peripheral neurons in siphon skin of Aplysia californica. , 1979, Journal of neurophysiology.

[4]  Central and peripheral control of siphon-withdrawal reflex in Aplysia californica. , 1979, Journal of neurophysiology.

[5]  E. Kandel,et al.  Classical conditioning in a simple withdrawal reflex in Aplysia californica , 1981, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[6]  E. Kandel,et al.  A cellular mechanism of classical conditioning in Aplysia: activity-dependent amplification of presynaptic facilitation. , 1983, Science.

[7]  J. Byrne,et al.  Associative conditioning of single sensory neurons suggests a cellular mechanism for learning. , 1983, Science.

[8]  E. Kandel,et al.  Differential classical conditioning of a defensive withdrawal reflex in Aplysia californica. , 1983, Science.

[9]  E. Kandel,et al.  Classical conditioning and sensitization share aspects of the same molecular cascade in Aplysia. , 1983, Cold Spring Harbor symposia on quantitative biology.

[10]  R. Hawkins.  A cellular mechanism of classical conditioning in Aplysia. , 1984, The Journal of experimental biology.

[11]  E. Kandel,et al.  A test of Hebb's postulate at identified synapses which mediate classical conditioning in Aplysia , 1984, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[12]  J. Byrne,et al.  Associative conditioning analog selectively increases cAMP levels of tail sensory neurons in Aplysia. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[13]  T. Carew,et al.  Invertebrate learning and memory: from behavior to molecules. , 1986, Annual review of neuroscience.

[14]  H. Wigström,et al.  Hippocampal long-term potentiation is induced by pairing single afferent volleys with intracellularly injected depolarizing current pulses. , 1986, Acta physiologica Scandinavica.

[15]  S. Kelso,et al.  Hebbian synapses in hippocampus. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[16]  E. Kandel,et al.  Effects of interstimulus interval and contingency on classical conditioning of the Aplysia siphon withdrawal reflex , 1986, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[17]  E. Kandel,et al.  Tail shock produces inhibition as well as sensitization of the siphon-withdrawal reflex of Aplysia: possible behavioral role for presynaptic inhibition mediated by the peptide Phe-Met-Arg-Phe-NH2. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[18]  J. Byrne.  Cellular analysis of associative learning. , 1987, Physiological reviews.

[19]  T. Teyler,et al.  Long-term potentiation. , 1987, Annual review of neuroscience.

[20]  Conditional discrimination learning in Aplysia californica , 1988, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[21]  R M Colwill,et al.  Context-US learning in Aplysia californica , 1988, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[22]  G. A. Clark,et al.  Classical conditioning of the Aplysia siphon-withdrawal reflex exhibits response specificity. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[23]  E T Walters.  Transformation of siphon responses during conditioning of Aplysia suggests a model of primitive stimulus-response association. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[24]  R. Hawkins,et al.  Identified serotonergic neurons LCB1 and RCB1 in the cerebral ganglia of Aplysia produce presynaptic facilitation of siphon sensory neurons , 1989, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[25]  S. Schacher,et al.  Identified facilitator neurons L29 and L28 are excited by cutaneous stimuli used in dishabituation, sensitization, and classical conditioning of Aplysia , 1989, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[26]  Aplysia(アメフラシ科)条件づけにおける水管反応の変換は原始的な刺激‐反応連関のモデルを示唆する , 1989 .

[27]  E. Kandel,et al.  Learning to modulate transmitter release: themes and variations in synaptic plasticity. , 1993, Annual review of neuroscience.

[28]  N Dale,et al.  L-glutamate may be the fast excitatory transmitter of Aplysia sensory neurons. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[29]  T. Bliss,et al.  A synaptic model of memory: long-term potentiation in the hippocampus , 1993, Nature.

[30]  V. Castellucci,et al.  Excitatory amino acid neurotransmission at sensory-motor and interneuronal synapses of Aplysia californica. , 1993, Journal of neurophysiology.

[31]  G. A. Clark,et al.  Activity-dependent enhancement of presynaptic facilitation provides a cellular mechanism for the temporal specificity of classical conditioning in Aplysia. , 1994, Learning & memory.

[32]  D. Glanzman.  Postsynaptic regulation of the development and long-term plasticity of Aplysia sensorimotor synapses in cell culture. , 1994, Journal of neurobiology.

[33]  D. Glanzman,et al.  Long-term potentiation of Aplysia sensorimotor synapses in cell culture: regulation by postsynaptic voltage , 1994, Proceedings of the Royal Society of London. Series B: Biological Sciences.

[34]  E. Kandel,et al.  cAMP contributes to mossy fiber LTP by initiating both a covalently mediated early phase and macromolecular synthesis-dependent late phase , 1994, Cell.

[35]  R. Nicoll,et al.  Mediation of hippocampal mossy fiber long-term potentiation by cyclic AMP. , 1994, Science.

[36]  E. Walters,et al.  Response-specific inhibition during general facilitation of defensive responses in Aplysia , 1994 .

[37]  E. Kandel,et al.  Pairing-specific, activity-dependent presynaptic facilitation at Aplysia sensory-motor neuron synapses in isolated cell culture , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[38]  D. Glanzman,et al.  Hebbian induction of long-term potentiation of Aplysia sensorimotor synapses: partial requirement for activation of an NMDA-related receptor , 1994, Proceedings of the Royal Society of London. Series B: Biological Sciences.

[39]  E. Kandel,et al.  Structure of the network mediating siphon-elicited siphon withdrawal in Aplysia. , 1995, Journal of neurophysiology.

[40]  I Rovira,et al.  Nitric oxide , 2021, Reactions Weekly.

[41]  Enhancement of sensorimotor connections by conditioning-related stimulation in Aplysia depends upon postsynaptic Ca2+. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[42]  E R Kandel,et al.  Presynaptic facilitation revisited: state and time dependence , 1996, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[43]  S. Tonegawa,et al.  The Essential Role of Hippocampal CA1 NMDA Receptor–Dependent Synaptic Plasticity in Spatial Memory , 1996, Cell.

[44]  E. Kandel,et al.  Control of Memory Formation Through Regulated Expression of a CaMKII Transgene , 1996, Science.

[45]  E R Kandel,et al.  Involvement of Pre- and Postsynaptic Mechanisms in Posttetanic Potentiation at Aplysia Synapses , 1997, Science.

[46]  E. Kandel,et al.  A Simplified Preparation for Relating Cellular Events to Behavior: Mechanisms Contributing to Habituation, Dishabituation, and Sensitization of the Aplysia Gill-Withdrawal Reflex , 1997, The Journal of Neuroscience.

[47]  D. Glanzman,et al.  Mediation of classical conditioning in Aplysia californica by long-term potentiation of sensorimotor synapses. , 1997, Science.

[48]  E R Kandel,et al.  A Simplified Preparation for Relating Cellular Events to Behavior: Contribution of LE and Unidentified Siphon Sensory Neurons to Mediation and Habituation of the Aplysia Gill- and Siphon-Withdrawal Reflex , 1997, The Journal of Neuroscience.

[49]  P M Balaban,et al.  The Synapse Between LE Sensory Neurons and Gill Motoneurons Makes Only a Small Contribution to the Aplysia Gill‐withdrawal Reflex , 1997, The European journal of neuroscience.

[50]  D. Glanzman,et al.  Effect of interstimulus interval on pairing-induced LTP of Aplysia sensorimotor synapses in cell culture. , 1997, Journal of neurophysiology.

[51]  LTP and learning: Let's stay together , 1997, Behavioral and Brain Sciences.

[52]  Zhongna Sun,et al.  Pathway-Specific Synaptic Plasticity: Activity-Dependent Enhancement and Suppression of Long-Term Heterosynaptic Facilitation at Converging Inputs on a Single Target , 1997, The Journal of Neuroscience.

[53]  Joseph E LeDoux,et al.  Fear conditioning induces associative long-term potentiation in the amygdala , 1997, Nature.

[54]  R. Hawkins,et al.  Nitric oxide as a retrograde messenger during long-term potentiation in hippocampus. , 1998, Progress in brain research.

[55]  E R Kandel,et al.  Classical conditioning, differential conditioning, and second-order conditioning of the Aplysia gill-withdrawal reflex in a simplified mantle organ preparation. , 1998, Behavioral neuroscience.

[56]  Eric R Kandel,et al.  Postsynaptic Induction and PKA-Dependent Expression of LTP in the Lateral Amygdala , 1998, Neuron.

[57]  Haruko Matsui,et al.  Inhibitory long-term potentiation underlies auditory conditioning of goldfish escape behaviour , 1998, Nature.

[58]  T. Abrams,et al.  Analysis of sequence-dependent interactions between transient calcium and transmitter stimuli in activating adenylyl cyclase in Aplysia: possible contribution to CS--US sequence requirement during conditioning. , 1998, Learning & memory.

[59]  Eric R. Kandel,et al.  Involvement of Presynaptic and Postsynaptic Mechanisms in a Cellular Analog of Classical Conditioning at AplysiaSensory-Motor Neuron Synapses in Isolated Cell Culture , 1998, The Journal of Neuroscience.

[60]  E R Kandel,et al.  Relationships between dishabituation, sensitization, and inhibition of the gill- and siphon-withdrawal reflex in Aplysia californica: effects of response measure, test time, and training stimulus. , 1998, Behavioral neuroscience.

[61]  E. Kandel,et al.  The Contribution of Facilitation of Monosynaptic PSPs to Dishabituation and Sensitization of the Aplysia Siphon Withdrawal Reflex , 1999, The Journal of Neuroscience.

[62]  J. Lübke,et al.  Importance of AMPA receptors for hippocampal synaptic plasticity but not for spatial learning. , 1999, Science.

[63]  J. Sanes,et al.  Development of the vertebrate neuromuscular junction. , 1999, Annual review of neuroscience.

[64]  Daniel Johnston,et al.  Multiple forms of LTP in hippocampal CA3 neurons use a common postsynaptic mechanism , 1999, Nature Neuroscience.

[65]  G. Murphy,et al.  Cellular Analog of Differential Classical Conditioning inAplysia: Disruption by the NMDA Receptor Antagonistdl-2-Amino-5-Phosphonovalerate , 1999, The Journal of Neuroscience.

[66]  S. Schacher,et al.  Changes in functional glutamate receptors on a postsynaptic neuron accompany formation and maturation of an identified synapse. , 1999, Journal of neurobiology.

[67]  P. Pavlidis,et al.  Presynaptic Protein Kinase Activity Supports Long-Term Potentiation at Synapses Between Individual Hippocampal Neurons , 2000, The Journal of Neuroscience.

[68]  E. Kandel,et al.  Is Heterosynaptic modulation essential for stabilizing hebbian plasiticity and memory , 2000, Nature Reviews Neuroscience.

[69]  M. Poo,et al.  Enhancement of presynaptic neuronal excitability by correlated presynaptic and postsynaptic spiking , 2000, Nature Neuroscience.

[70]  E R Kandel,et al.  The Contribution of Activity-Dependent Synaptic Plasticity to Classical Conditioning in Aplysia , 2001, The Journal of Neuroscience.

[71]  R. Hawkins,et al.  Presynaptic Role of cGMP-Dependent Protein Kinase during Long-Lasting Potentiation , 2001, The Journal of Neuroscience.

[72]  S. Heinemann,et al.  Trans-Synaptic Eph Receptor-Ephrin Signaling in Hippocampal Mossy Fiber LTP , 2002, Science.

[73]  Eric R. Kandel,et al.  Fear Conditioning Occludes LTP-Induced Presynaptic Enhancement of Synaptic Transmission in the Cortical Pathway to the Lateral Amygdala , 2002, Neuron.