Balanced Adjustable Mirrored Current Source with Common Mode Feedback and Output Measurement for Bioimpedance Applications

Bioimpedance methods are used in a variety of applications such as impedance tomography, electrodermal activity detection and vascular disease assessment. Recent developments in portable and unobtrusive biosignal acquisition systems facilitate the integration of wearable bioimpedance applications including sleep monitoring, respiration estimation and fluid monitoring. However, the less stable measurement situation in a wearable scenario increases the requirements for the system’s accuracy and adaptability. The current source of a bioimpedance system needs to drive large complex loads subject to vast variations over time while maintaining a high level of accuracy. The widely used improved Howland current source suffers from multiple disadvantages when considered for an adaptive bioimpedance system. We propose an optimized mirrored architecture which allows for a simple output current adjustment and current measurement without an additional shunt resistor in the load path. The system implements a common mode feedback system which includes balancing of the mirrored sources. Our design is validated by calculation, SPICE simulation and complex load measurements. We achieved output impedances in excess of 3 MΩ and derived a simplified transconductance function valid for frequencies up to 1 MHz. We conclude that the presented architecture is an important step forward towards accurate wearable bioimpedance acquisition. Employing generalized impedance converters, the output impedance could be further optimized.

[1]  Rosalind J. Sadleir,et al.  Biocompatible, High Precision, Wideband, Improved Howland Current Source With Lead-Lag Compensation , 2013, IEEE Transactions on Biomedical Circuits and Systems.

[2]  Fernando Seoane,et al.  An analog front-end enables electrical impedance spectroscopy system on-chip for biomedical applications , 2008, Physiological measurement.

[3]  Eung Je Woo,et al.  Calibration methods for a multi-channel multi-frequency EIT system , 2007, Physiological measurement.

[4]  Amin Mahnam,et al.  Comprehensive study of Howland circuit with non-ideal components to design high performance current pumps , 2016 .

[5]  Yang Zhang,et al.  Tomo: Wearable, Low-Cost Electrical Impedance Tomography for Hand Gesture Recognition , 2015, UIST.

[6]  F. Noveletto,et al.  Analog Front-End for the Integrated Circuit AD5933 Used in Electrical Bioimpedance Measurements , 2016 .

[8]  Gaetano D Gargiulo,et al.  Peripheral vascular disease assessment in the lower limb: a review of current and emerging non-invasive diagnostic methods , 2018, Biomedical engineering online.

[9]  G.J. Saulnier,et al.  ACT3: a high-speed, high-precision electrical impedance tomograph , 1991, IEEE Transactions on Biomedical Engineering.

[10]  Reinhold Orglmeister,et al.  Short Distance Impedance Pneumography , 2018 .

[11]  Alexandre Felipe,et al.  High Accurate Howland Current Source: Output Constraints Analysis , 2013 .

[12]  Fernando Seoane,et al.  A Handheld and Textile-Enabled Bioimpedance System for Ubiquitous Body Composition Analysis. An Initial Functional Validation , 2017, IEEE Journal of Biomedical and Health Informatics.