Factors Associated with Asthma Symptoms in Schoolchildren from Greece: The Physical Activity, Nutrition and Allergies in Children Examined in Athens (PANACEA) Study

To evaluate whether dietary habits and anthropometric and lifestyle characteristics are associated with the prevalence of asthma symptoms, a sample of 700 Greek schoolchildren were evaluated through a standardized questionnaire. Body height and weight were measured, and body mass index was calculated. Multiple logistic regression and multivariate techniques (principal components analysis) were performed. Overall lifetime prevalence for asthma symptoms was found to be 23.7%. Increased body weight, sedentary lifestyle, and consumption of sulphur-dioxide-enriched foods and beverages seem to promote asthma symptoms, while avoidance of this chemical preservative and physical activity was associated with reduced odds of reporting asthma symptoms.

[1]  L. Epstein,et al.  Determinants of physical activity and interventions in youth. , 1992, Medicine and science in sports and exercise.

[2]  M. Suzuki,et al.  Parental obesity and overweight affect the body‐fat accumulation in the offspring: the possible effect of a high‐fat diet through epigenetic inheritance , 2006, Obesity reviews : an official journal of the International Association for the Study of Obesity.

[3]  D. Solé,et al.  Obesity and Its Relationship with Asthma Prevalence and Severity in Adolescents from Southern Brazil , 2006, The Journal of asthma : official journal of the Association for the Care of Asthma.

[4]  A. Stipić-Marković,et al.  [Prevalence of symptoms of asthma, allergic rhinitis, conjunctivitis and atopic eczema: ISAAC (International Study of Asthma and Allergies in Childhood) in a population of schoolchildren in Zagreb]. , 2003, Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti.

[5]  D. Mannino,et al.  Dietary intake, physical activity, body mass index, and childhood asthma in the third national health and nutrition survey (NHANES III) , 2004, Pediatric pulmonology.

[6]  C. Saçkesen,et al.  Prevalence of asthmatic phenotypes and bronchial hyperresponsiveness in Turkish schoolchildren: an International Study of Asthma and Allergies in Childhood (ISAAC) phase 2 study. , 2003, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

[7]  B. Freedman Sulphur dioxide in foods and beverages: its use as a preservative and its effect on asthma. , 1980, British journal of diseases of the chest.

[8]  S. Guerra,et al.  Persistence of asthma symptoms during adolescence: role of obesity and age at the onset of puberty. , 2004, American journal of respiratory and critical care medicine.

[9]  K. Berhane,et al.  Obesity and the risk of newly diagnosed asthma in school-age children. , 2003, American journal of epidemiology.

[10]  D. Panagiotakos,et al.  Aims, methods and preliminary findings of the Physical Activity, Nutrition and Allergies in Children Examined in Athens (PANACEA) epidemiological study , 2007, BMC public health.

[11]  D. Panagiotakos,et al.  Prevalence of asthma among schoolchildren in Patras, Greece: four questionnaire surveys during 1978–2003 , 2006, Archives of Disease in Childhood.

[12]  K. Flegal,et al.  Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002. , 2004, JAMA.

[13]  P. Cassano,et al.  Relationship of serum antioxidants to asthma prevalence in youth. , 2004, American journal of respiratory and critical care medicine.

[14]  A. Pistorio,et al.  Relationship between body mass index and asthma characteristics in a group of Italian children and adolescents. , 2005, The Journal of asthma : official journal of the Association for the Care of Asthma.

[15]  J. Castro‐Rodriguez,et al.  A different pattern of risk factors for atopic and non‐atopic wheezing in 9–12‐year‐old children , 2005, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

[16]  Richard Beasley,et al.  Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC , 1998, The Lancet.

[17]  A. Papadimitriou,et al.  Prevalence of Obesity in Elementary Schoolchildren Living in Northeast Attica, Greece , 2006, Obesity.

[18]  J. Choung,et al.  The Prevalence of Atopy and Asthma among University Freshmen in Seoul, Korea: Association with Obesity , 2007, The Journal of asthma : official journal of the Association for the Care of Asthma.

[19]  Gregory Titus,et al.  Hypercholesterolemia is a Potential Risk Factor for Asthma , 2006, The Journal of asthma : official journal of the Association for the Care of Asthma.

[20]  D. Strachan,et al.  Phase II of the International Study of Asthma and Allergies in Childhood (ISAAC II): rationale and methods , 2004, European Respiratory Journal.

[21]  G. Krassas Thyroid Eye Disease in Children and Adolescents - New Therapeutic Approaches , 2001, Journal of pediatric endocrinology & metabolism : JPEM.

[22]  T. Tzotzas,et al.  Prevalence and trends in overweight and obesity among children and adolescents in Thessaloniki, Greece. , 2001, Journal of pediatric endocrinology & metabolism : JPEM.

[23]  A. Litonjua,et al.  Association of body mass with pulmonary function in the Childhood Asthma Management Program (CAMP) , 2003, Thorax.

[24]  M. Michalopoulou,et al.  Validity and reliability of physical activity measures in greek high school age children. , 2004, Journal of sports science & medicine.

[25]  A. McPherson,et al.  Asthma as a Barrier to Children's Physical Activity: Implications for Body Mass Index and Mental Health , 2006, Pediatrics.

[26]  T. Fok,et al.  The effects of obesity on pulmonary function , 2003, Archives of disease in childhood.

[27]  S. Weiland,et al.  Asthma and allergies among children in West and East Germany: a comparison between Münster and Greifswald using the ISAAC phase I protocol. International Study of Asthma and Allergies in Childhood. , 1998, The European respiratory journal.

[28]  A. Smith,et al.  Is there a relationship between asthma and dental erosion? A case control study. , 2002, International journal of paediatric dentistry.

[29]  A. Custovic,et al.  Dietary intake in sensitized children with recurrent wheeze and healthy controls: a nested case–control study , 2006, Allergy.

[30]  T. Cole,et al.  Establishing a standard definition for child overweight and obesity worldwide: international survey , 2000, BMJ : British Medical Journal.

[31]  H. Steinman,et al.  The effects of soft-drink preservatives on asthmatic children. , 1986, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.

[32]  E. Vandewater,et al.  Linking obesity and activity level with children's television and video game use. , 2004, Journal of adolescence.

[33]  S. Muro,et al.  High sensitivity C-reactive protein in asthma , 2006, European Respiratory Journal.