Lab-on-a-Chip Device and System for Point-of-Care Applications

[1]  Zhen-Li Huang,et al.  Preparation of silica encapsulated quantum dot encoded beads for multiplex assay and its properties. , 2006, Analytical biochemistry.

[2]  S Xiong,et al.  An optofluidic prism tuned by two laminar flows. , 2011, Lab on a chip.

[3]  Monitoring CD4 in whole blood with an opto‐fluidic detector based on spatially modulated fluorescence emission , 2011, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

[4]  Guoan Zheng,et al.  Optical imaging techniques in microfluidics and their applications. , 2012, Lab on a chip.

[5]  Hongying Zhu,et al.  Opto-fluidic micro-ring resonator for sensitive label-free viral detection. , 2008, The Analyst.

[6]  K. Foley,et al.  Measuring surface charge density and particle height using surface plasmon resonance technique. , 2010, Analytical chemistry.

[7]  Yeshaiahu Fainman,et al.  Optofluidic devices and applications in photonics, sensing and imaging. , 2012, Lab on a chip.

[8]  Romeo Bernini,et al.  Integrated tunable liquid optical fiber. , 2012, Lab on a chip.

[9]  B. Liedberg,et al.  Biosensing with surface plasmon resonance--how it all started. , 1995, Biosensors & bioelectronics.

[10]  S. S. Gorthi,et al.  Microfabricated multiple field of view imaging flow cytometry. , 2012, Lab on a chip.

[11]  Luca Pion-Tonachini,et al.  An optical-coding method to measure particle distribution in microfluidic devices. , 2011, AIP advances.

[12]  Nicole K Henderson-Maclennan,et al.  Deformability-based cell classification and enrichment using inertial microfluidics. , 2011, Lab on a chip.

[13]  G. Whitesides,et al.  Dynamic control of liquid-core/liquid-cladding optical waveguides , 2004, (CLEO). Conference on Lasers and Electro-Optics, 2005..

[14]  D Haussler,et al.  Knowledge-based analysis of microarray gene expression data by using support vector machines. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[15]  Paul Galvin,et al.  Emerging optofluidic technologies for point-of-care genetic analysis systems: a review , 2009, Analytical and bioanalytical chemistry.

[16]  Jörg Peter Kutter,et al.  PIV measurements in a microfluidic 3D-sheathing structure with three-dimensional flow behaviour , 2002 .

[17]  L. Hood,et al.  Integrated barcode chips for rapid, multiplexed analysis of proteins in microliter quantities of blood , 2008, Nature Biotechnology.

[18]  Yu-Hwa Lo,et al.  Two-parameter angular light scatter collection for microfluidic flow cytometry by unique waveguide structures , 2010, Biomedical optics express.

[19]  V. Lien,et al.  Fluidic photonic integrated circuit for in-line detection , 2005 .

[20]  Hans Peter Herzig,et al.  Performance of an integrated microoptical system for fluorescence detection in microfluidic systems. , 2002, Analytical chemistry.

[21]  J. Kutter,et al.  Integrating advanced functionality in a microfabricated high-throughput fluorescent-activated cell sorter. , 2003, Lab on a chip.

[22]  Hong Wu,et al.  A microfluidic platform for systems pathology: multiparameter single-cell signaling measurements of clinical brain tumor specimens. , 2010, Cancer research.

[23]  Yuze Sun,et al.  Sensitive optical biosensors for unlabeled targets: a review. , 2008, Analytica chimica acta.

[24]  Yi-Chung Tung,et al.  Optofluidic detection for cellular phenotyping. , 2012, Lab on a chip.

[25]  D. Psaltis,et al.  Developing optofluidic technology through the fusion of microfluidics and optics , 2006, Nature.

[26]  Alex Groisman,et al.  Two-dimensional hydrodynamic focusing in a simple microfluidic device , 2005 .

[27]  R. Dasari,et al.  Single Molecule Detection Using Surface-Enhanced Raman Scattering (SERS) , 1997 .

[28]  A. Ladd,et al.  Inertial migration of neutrally buoyant particles in a square duct: An investigation of multiple equilibrium positions , 2006 .

[29]  Jeffrey S Erickson,et al.  Two simple and rugged designs for creating microfluidic sheath flow. , 2008, Lab on a chip.

[30]  K. Foley,et al.  A label-free optical detection method for biosensors and microfluidics , 2008 .

[31]  Seung‐Man Yang,et al.  Fluorescent liquid-core/air-cladding waveguides towards integrated optofluidic light sources. , 2008, Lab on a chip.

[32]  A. Hawkins,et al.  The photonic integration of non-solid media using optofluidics , 2011 .

[33]  L. Blum,et al.  DNA biosensors and microarrays. , 2008, Chemical reviews.

[34]  P. Kiesel,et al.  Spatially modulated fluorescence emission from moving particles , 2009 .

[35]  V. Lien,et al.  Integrated Fluidic Photonics for Multi-Parameter In-Plane Detection in Microfluidic Flow Cytometry , 2006, LEOS 2006 - 19th Annual Meeting of the IEEE Lasers and Electro-Optics Society.

[36]  A. Liu,et al.  Label-free detection with micro optical fluidic systems (MOFS): a review , 2008, Analytical and bioanalytical chemistry.

[37]  Shuming Nie,et al.  Quantum dot-encoded mesoporous beads with high brightness and uniformity: rapid readout using flow cytometry. , 2004, Analytical chemistry.

[38]  B. Liedberg,et al.  Principles of biosensing with an extended coupling matrix and surface plasmon resonance , 1993 .

[39]  Ethan Schonbrun,et al.  High-throughput fluorescence detection using an integrated zone-plate array. , 2010, Lab on a chip.

[40]  Seung‐Man Yang,et al.  Liquid–liquid fluorescent waveguides using microfluidic-drifting-induced hydrodynamic focusing , 2011 .

[41]  Y. K. Cheung,et al.  1 Supplementary Information for : Microfluidics-based diagnostics of infectious diseases in the developing world , 2011 .

[42]  Ryuji Koyama,et al.  Counting and sizing of particles and particle agglomerates in a microfluidic device using laser light scattering: application to a particle-enhanced immunoassay. , 2003, Lab on a chip.

[43]  Luke P. Lee,et al.  Disposable integrated microfluidics with self-aligned planar microlenses , 2004 .

[44]  Zhe Mei,et al.  Label-free Optofluidic Cell Classifier Utilizing Support Vector Machines. , 2013, Sensors and actuators. B, Chemical.

[45]  Xudong Fan,et al.  Optofluidic Microsystems for Chemical and Biological Analysis. , 2011, Nature photonics.

[46]  Aaron R. Hawkins,et al.  Handbook of Optofluidics , 2010 .

[47]  N. Sundararajan,et al.  Three-dimensional hydrodynamic focusing in polydimethylsiloxane (PDMS) microchannels , 2004, Journal of Microelectromechanical Systems.

[48]  Yu-Hwa Lo,et al.  Human mammalian cell sorting using a highly integrated micro-fabricated fluorescence-activated cell sorter (microFACS). , 2010, Lab on a chip.

[49]  Xinping Huang,et al.  Label-free imaging, detection, and mass measurement of single viruses by surface plasmon resonance , 2010, Proceedings of the National Academy of Sciences.

[50]  A D Stroock,et al.  An integrated fluorescence detection system in poly(dimethylsiloxane) for microfluidic applications. , 2001, Analytical chemistry.

[51]  Sumita Pennathur,et al.  Optofluidics: field or technique? , 2008, Lab on a chip.

[52]  Y. Lo,et al.  Lab-on-a-chip flow cytometer employing color-space-time coding. , 2010, Applied physics letters.

[53]  Sindy K. Y. Tang,et al.  Dynamically reconfigurable liquid-core liquid-cladding lens in a microfluidic channel. , 2008, Lab on a chip.

[54]  V. Lien,et al.  High-sensitivity cytometric detection using fluidic-photonic integrated circuits with array waveguides , 2005, IEEE Journal of Selected Topics in Quantum Electronics.

[55]  R. Tompkins,et al.  Continuous inertial focusing, ordering, and separation of particles in microchannels , 2007, Proceedings of the National Academy of Sciences.

[56]  Yu-Hwa Lo,et al.  Review Article: Recent advancements in optofluidic flow cytometer. , 2010, Biomicrofluidics.

[57]  R. Austin,et al.  Hydrodynamic Focusing on a Silicon Chip: Mixing Nanoliters in Microseconds , 1998 .

[58]  Y. Lo,et al.  Optofluidic device for label-free cell classification from whole blood. , 2012, Lab on a chip.

[59]  A. Bhagat,et al.  Inertial microfluidics for continuous particle filtration and extraction , 2009 .

[60]  Paul Yager,et al.  Chemical signal amplification in two-dimensional paper networks. , 2010, Sensors and actuators. B, Chemical.

[61]  V. Lien,et al.  Demonstration of two-dimensional fluidic lens for integration into microfluidic flow cytometers , 2006 .

[62]  Zhe Mei,et al.  Universally applicable three-dimensional hydrodynamic microfluidic flow focusing. , 2013, Lab on a chip.

[63]  C. Bliss,et al.  Integrated wavelength-selective optical waveguides for microfluidic-based laser-induced fluorescence detection. , 2008, Lab on a chip.

[64]  Ruey-Jen Yang,et al.  Three-dimensional hydrodynamic focusing in two-layer polydimethylsiloxane (PDMS) microchannels , 2007 .

[65]  Yi Zhang,et al.  An integrated fluorescence detection system for lab-on-a-chip applications. , 2007, Lab on a chip.

[66]  Chun-Hao Chen,et al.  Microfluidics and photonics for Bio‐System‐on‐a‐Chip: A review of advancements in technology towards a microfluidic flow cytometry chip , 2008, Journal of biophotonics.

[67]  Sungyoung Choi,et al.  Three-dimensional hydrodynamic focusing with a single sheath flow in a single-layer microfluidic device. , 2009, Lab on a chip.

[68]  David S Boyle,et al.  Emerging technologies for point-of-care CD4 T-lymphocyte counting. , 2012, Trends in biotechnology.

[69]  Lipo Wang.  Support vector machines : theory and applications , 2005 .

[70]  Stefan Andersson-Engels,et al.  Numerical simulations of light scattering by red blood cells , 2005, IEEE Transactions on Biomedical Engineering.

[71]  Ramasamy Manoharan,et al.  Detection and identification of a single DNA base molecule using surface-enhanced Raman scattering (SERS) , 1998 .

[72]  Christelle Monat,et al.  Integrated optofluidics: A new river of light , 2007 .

[73]  Feng Chu,et al.  Applications of support vector machines to cancer classification with microarray data , 2005, Int. J. Neural Syst..

[74]  R. Tsien,et al.  On/off blinking and switching behaviour of single molecules of green fluorescent protein , 1997, Nature.

[75]  Daniel L. Feeback,et al.  Microfabrication and test of a three-dimensional polymer hydro-focusing unit for flow cytometry applications , 2005 .

[76]  T. Poggio,et al.  Multiclass cancer diagnosis using tumor gene expression signatures , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[77]  Gabriel A Kwong,et al.  DNA-encoded antibody libraries: a unified platform for multiplexed cell sorting and detection of genes and proteins. , 2007, Journal of the American Chemical Society.

[78]  Tony Jun Huang,et al.  "Microfluidic drifting"--implementing three-dimensional hydrodynamic focusing with a single-layer planar microfluidic device. , 2007, Lab on a chip.

[79]  G. Whitesides,et al.  Soft lithography for micro- and nanoscale patterning , 2010, Nature Protocols.

[80]  E. Kroeger,et al.  Reflection and transmission of light by a rough surface, including results for surface-plasmon effects , 1975 .

[81]  Y. Lo,et al.  Optofluidic Waveguides in Teflon AF-Coated PDMS Microfluidic Channels , 2009, IEEE Photonics Technology Letters.

[82]  Martin Moskovits,et al.  Free-surface microfluidic control of surface-enhanced Raman spectroscopy for the optimized detection of airborne molecules , 2007, Proceedings of the National Academy of Sciences.

[83]  George M. Whitesides,et al.  Integrated fluorescent light source for optofluidic applications , 2005 .

[84]  Luca Pion-Tonachini,et al.  Applying an optical space-time coding method to enhance light scattering signals in microfluidic devices. , 2011, Biomicrofluidics.