Benzodiazepines, glia, and HIV-1 neuropathogenesis

[1]  P. Peterson,et al.  Diazepam-mediated inhibition of human immunodeficiency virus type 1 expression in human brain cells , 1997, Antimicrobial agents and chemotherapy.

[2]  D. Hardy,et al.  The Kidney Androgen-regulated Protein Promoter Confers Renal Proximal Tubule Cell-specific and Highly Androgen-responsive Expression on the Human Angiotensinogen Gene in Transgenic Mice* , 1997, The Journal of Biological Chemistry.

[3]  Shuxian Hu,et al.  IL‐1‐induced iNOS expression in human astrocytes via NF‐κB , 1997 .

[4]  L. Ignarro,et al.  Inducible Nitric-oxide Synthase and Nitric Oxide Production in Human Fetal Astrocytes and Microglia , 1997, The Journal of Biological Chemistry.

[5]  B. Brew,et al.  Levels of human immunodeficiency virus type 1 RNA in cerebrospinal fluid correlate with AIDS dementia stage. , 1997, The Journal of infectious diseases.

[6]  L. Ehrlich,et al.  Proinflammatory cytokines inhibit HIV-1(SF162) expression in acutely infected human brain cell cultures. , 1997, Journal of immunology.

[7]  J. Sodroski,et al.  CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia , 1997, Nature.

[8]  Justin C. McArthur,et al.  Immunologic NO Synthase: Elevation in Severe AIDS Dementia and Induction by HIV-1 gp41 , 1996, Science.

[9]  T. Clark,et al.  Investigation of the Uncatalyzed Hydration of CO2 and First Approximations to the Active Site of Carbonic Anhydrase - A Combined Ab initio and DFT Study - , 1996 .

[10]  D. Thomas,et al.  Permanent occupancy of the human immunodeficiency virus type 1 enhancer by NF-kappa B is needed for persistent viral replication in monocytes , 1996, Journal of virology.

[11]  G. Nuovo,et al.  AIDS Dementia Is Associated with Massive, Activated HIV-1 Infection and Concomitant Expression of Several Cytokines , 1996, Molecular medicine.

[12]  G. Bren,et al.  The Ras-Raf pathway is activated in human immunodeficiency virus-infected monocytes and particpates in the activation of NF-kappa B , 1996, Journal of virology.

[13]  M. Bukrinsky,et al.  Cytokine‐stimulated astrocytes damage human neurons via a nitric oxide mechanism , 1996, Glia.

[14]  E. Carboni,et al.  Characterization of peripheral benzodiazepine type sites in a cultured murine BV‐2 microglial cell line , 1996, Glia.

[15]  Shuxian Hu,et al.  Differential regulation by cytokines of human astrocyte nitric oxide production , 1995, Glia.

[16]  J. Merrill,et al.  Human immunodeficiency virus 1 envelope proteins induce interleukin 1, tumor necrosis factor alpha, and nitric oxide in glial cultures derived from fetal, neonatal, and adult human brain , 1995, The Journal of experimental medicine.

[17]  F. Scaravilli,et al.  Programmed cell death in brains of HIV-1-positive pre-AIDS patients , 1995, The Lancet.

[18]  M. Wainberg,et al.  Regulation of human immunodeficiency virus type 1 and cytokine gene expression in myeloid cells by NF-kappa B/Rel transcription factors , 1995, Microbiological reviews.

[19]  I. Elovaara,et al.  Abundant expression of HIV Nef and Rev proteins in brain astrocytes in vivo is associated with dementia , 1995, AIDS.

[20]  K. Fowke,et al.  Infection of Human Fetal Astrocytes with HIV‐1: Viral Tropism and the Role of Cell to Cell Contact in Viral Transmission , 1995, Journal of neuropathology and experimental neurology.

[21]  Howard E. Gendelman,et al.  Dementia Associated with the Acquired Immunodeficiency Syndrome , 1995 .

[22]  A. Rizzino,et al.  A regulatory role for astrocytes in HIV-1 encephalitis. An overexpression of eicosanoids, platelet-activating factor, and tumor necrosis factor-alpha by activated HIV-1-infected monocytes is attenuated by primary human astrocytes. , 1995, Journal of immunology.

[23]  C. Park,et al.  Benzodiazepines and peptides stimulate pregnenolone synthesis in brain mitochondria. , 1995, European journal of pharmacology.

[24]  R. Brownstone,et al.  Human immunodeficiency virus type 1 tat activates non—N‐methyl‐D‐aspartate excitatory amino acid receptors and causes neurotoxicity , 1995, Annals of neurology.

[25]  S. Lipton,et al.  Regulation of nitric oxide synthase activity in human immunodeficiency virus type 1 (HIV-1)-infected monocytes: implications for HIV- associated neurological disease , 1995, The Journal of experimental medicine.

[26]  J. Mills,et al.  HIV replication in chronically infected macrophages is not inhibited by the Tat inhibitors Ro‐5‐3335 and Ro‐24‐7429 , 1994, Journal of leukocyte biology.

[27]  Shuxian Hu,et al.  Nitric oxide production and neurotoxicity mediated by activated microglia from human versus mouse brain. , 1994, The Journal of infectious diseases.

[28]  Takahiro Matsumoto,et al.  Effect of peripheral benzodiazepine receptor ligands on lipopolysaccharide-induced tumor necrosis factor activity in thioglycolate-treated mice , 1994, Antimicrobial Agents and Chemotherapy.

[29]  C. Ambrosino,et al.  The expression of the interleukin 6 gene is induced by the human immunodeficiency virus 1 TAT protein , 1994, The Journal of experimental medicine.

[30]  M. Norenberg,et al.  Characterization of the peripheral‐type benzodiazepine receptors in cultured astrocytes: Evidence for multiplicity , 1993, Glia.

[31]  E. Major,et al.  Human immunodeficiency virus type 1 infection of the brain , 1993, Clinical Microbiology Reviews.

[32]  J. Hiscott,et al.  Chronic human immunodeficiency virus type 1 infection stimulates distinct NF-kappa B/rel DNA binding activities in myelomonoblastic cells , 1993, Journal of virology.

[33]  D. Dickson,et al.  Induction of nitric oxide synthase activity in human astrocytes by interleukin-1β and interferon-γ , 1993, Journal of Neuroimmunology.

[34]  D. Dickson,et al.  Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease , 1993, Glia.

[35]  E. Masliah,et al.  Cellular neuropathology in HIV encephalitis , 1992, Journal of the Neurological Sciences.

[36]  S. Lipton.  Requirement for macrophages in neuronal injury induced by HIV envelope protein gp120. , 1992, Neuroreport.

[37]  R. Hay,et al.  NF-kappa B-dependent induction of the NF-kappa B p50 subunit gene promoter underlies self-perpetuation of human immunodeficiency virus transcription in monocytic cells. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[38]  M. Gavish,et al.  Immunomodulatory effect of peripheral benzodiazepine receptor ligands on human mononuclear cells , 1992, Journal of Neuroimmunology.

[39]  W. Kaufmann.  Cerebrocortical changes in AIDS. , 1992, Laboratory investigation; a journal of technical methods and pathology.

[40]  W. Farrar,et al.  The HIV-1 gp120 envelope protein has the intrinsic capacity to stimulate monokine secretion. , 1991, Journal of immunology.

[41]  F. Arenzana‐Seisdedos,et al.  HIV enhancer activity perpetuated by NF-κB induction on infection of monocytes , 1991, Nature.

[42]  B. Spire,et al.  Induction of NF-KB during monocyte differentiation by HIV type 1 infection. , 1991, Journal of immunology.

[43]  B. Descamps-Latscha,et al.  In vivo treatment with benzodiazepines inhibits murine phagocyte oxidative metabolism and production of interleukin 1, tumor necrosis factor and interleukin-6. , 1990, The Journal of pharmacology and experimental therapeutics.

[44]  C. Kufta,et al.  Specific tropism of HIV-1 for microglial cells in primary human brain cultures. , 1990, Science.

[45]  S. Lipton,et al.  HIV-1 coat protein neurotoxicity prevented by calcium channel antagonists. , 1990, Science.

[46]  P. Baeuerle,et al.  Regulation of tumor necrosis factor alpha transcription in macrophages: involvement of four kappa B-like motifs and of constitutive and inducible forms of NF-kappa B , 1990, Molecular and cellular biology.

[47]  W. Schaffner,et al.  Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. , 1989, Nucleic acids research.

[48]  H. Gendelman,et al.  The macrophage in the persistence and pathogenesis of HIV infection. , 1989, AIDS.

[49]  Karen L. Elkins,et al.  Neuronal cell killing by the envelope protein of HIV and its prevention by vasoactive intestinal peptide , 1988, Nature.

[50]  J. Sidtis,et al.  The brain in AIDS: central nervous system HIV-1 infection and AIDS dementia complex. , 1988, Science.

[51]  H. Gendelman,et al.  Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy. , 1986, Science.

[52]  F. Zavala,et al.  Interaction of benzodiazepines with mouse macrophages. , 1984, European journal of pharmacology.

[53]  G. Le Fur,et al.  Peripheral benzodiazepine binding sites: effect of PK 11195, 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide. I. In vitro studies. , 1983, Life sciences.

[54]  H. Schoemaker,et al.  Specific high-affinity saturable binding of [3H] R05-4864 to benzodiazepine binding sites in the rat cerebral cortex. , 1981, European journal of pharmacology.

[55]  C. Braestrup,et al.  Some properties of brain specific benzodiazepine receptors: New evidence for multiple receptors , 1979, Pharmacology Biochemistry and Behavior.

[56]  H. Mohler,et al.  Benzodiazepine receptor: demonstration in the central nervous system , 1977, Science.

[57]  C. Braestrup,et al.  Specific benzodiazepine receptors in rat brain characterized by high-affinity (3H)diazepam binding. , 1977, Proceedings of the National Academy of Sciences of the United States of America.

[58]  C. Braestrup,et al.  Benzodiazepine receptors in rat brain , 1977, Nature.

[59]  L. Mucke,et al.  Pathogenesis of HIV-1 associated neurodegeneration. , 1996, Critical reviews in neurobiology.

[60]  P. Peterson,et al.  Glia, cytokines, and neurotoxicity. , 1995, Critical reviews in neurobiology.

[61]  C. Petito,et al.  Evidence of apoptotic cell death in HIV encephalitis. , 1995, The American journal of pathology.

[62]  R. Drugan,et al.  Are the nonmitochondrial peripheral benzodiazepine receptors on leukocytes a novel intermediary of brain, behavior, and immunity? , 1994, Laboratory investigation; a journal of technical methods and pathology.

[63]  E. Benveniste.  Cytokine circuits in brain. Implications for AIDS dementia complex. , 1994, Research publications - Association for Research in Nervous and Mental Disease.

[64]  Shuxian Hu,et al.  Tumor necrosis factor-alpha potentiates glutamate neurotoxicity in human fetal brain cell cultures. , 1994, Developmental neuroscience.

[65]  P. Casellas,et al.  Distribution profile and properties of peripheral-type benzodiazepine receptors on human hemopoietic cells. , 1993, Life sciences.

[66]  D. Dickson,et al.  Induction of nitric oxide synthase activity in human astrocytes by interleukin-1 beta and interferon-gamma. , 1993, Journal of neuroimmunology.

[67]  R. Pauwels.  Discovery of TIBO, a New Family of HIV-1-Specific Reverse Transcriptase Inhibitors , 1993 .

[68]  S. Tam,et al.  A New Approach to Antiviral Chemotherapy: Intervention in Viral Gene Expression by HIV Tat Antagonists , 1993 .

[69]  Y. Oh,et al.  Interleukin-1-beta and tumor necrosis factor-alpha increase peripheral-type benzodiazepine binding sites in cultured polygonal astrocytes. , 1992, Journal of Neurochemistry.

[70]  F. Arenzana‐Seisdedos,et al.  HIV enhancer activity perpetuated by NF-kappa B induction on infection of monocytes. , 1991, Nature.

[71]  E. Vivés,et al.  Evidence for neurotoxic activity of tat from human immunodeficiency virus type 1. , 1991, Journal of virology.

[72]  L. Hertz,et al.  Pharmacological characteristics of diazepam receptors in neurons and astrocytes in primary cultures , 1987, Journal of neuroscience research.