Comprehensive pathway‐based interrogation of genetic variations in the nucleotide excision DNA repair pathway and risk of bladder cancer

Growing evidence suggests that single nucleotide polymorphisms (SNPs) in nucleotide excision repair (NER) pathway genes play an important role in bladder cancer etiology. However, only a limited number of genes and variations in this pathway have been evaluated to date.

[1]  William Wheeler,et al.  A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci , 2010, Nature Genetics.

[2]  A. Jemal,et al.  Cancer Statistics, 2010 , 2010, CA: a cancer journal for clinicians.

[3]  H. Morgenstern,et al.  Associations between NBS1 polymorphisms, haplotypes and smoking-related cancers. , 2010, Carcinogenesis.

[4]  Melissa Bondy,et al.  Polymorphisms of LIG4, BTBD2, HMGA2, and RTEL1 genes involved in the double-strand break repair pathway predict glioblastoma survival. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[5]  F. Clavel-Chapelon,et al.  Polymorphisms in fatty-acid-metabolism-related genes are associated with colorectal cancer risk. , 2010, Carcinogenesis.

[6]  Jian Gu,et al.  Novel Susceptibility Loci for Second Primary Tumors/Recurrence in Head and Neck Cancer Patients: Large-Scale Evaluation of Genetic Variants , 2009, Cancer Prevention Research.

[7]  L. Kiemeney,et al.  The present and future burden of urinary bladder cancer in the world , 2009, World Journal of Urology.

[8]  David B. Goldstein,et al.  A Genome-Wide Investigation of SNPs and CNVs in Schizophrenia , 2009, PLoS genetics.

[9]  L. Kiemeney,et al.  Epidemiology and genetic susceptibility to bladder cancer , 2008, BJU international.

[10]  D. Campa,et al.  A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of non-small cell lung cancer in smokers. , 2008, Carcinogenesis.

[11]  J. Wakefield,et al.  Sequence Variants of NAT1 and NAT2 and Other Xenometabolic Genes and Risk of Lung and Aerodigestive Tract Cancers in Central Europe , 2008, Cancer Epidemiology Biomarkers & Prevention.

[12]  M. Boehnke,et al.  So many correlated tests, so little time! Rapid adjustment of P values for multiple correlated tests. , 2007, American journal of human genetics.

[13]  M. Spitz,et al.  Projecting individualized probabilities of developing bladder cancer in white individuals. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[14]  J. Gu,et al.  High-order interactions among genetic polymorphisms in nucleotide excision repair pathway genes and smoking in modulating bladder cancer risk. , 2007, Carcinogenesis.

[15]  Paolo Vineis,et al.  DNA Repair Polymorphisms Modify Bladder Cancer Risk: A Multi-factor Analytic Strategy , 2007, Human Heredity.

[16]  Jon Wakefield,et al.  A Bayesian measure of the probability of false discovery in genetic epidemiology studies. , 2007, American journal of human genetics.

[17]  D. Harrison,et al.  E2F regulates DDB2: consequences for DNA repair in Rb-deficient cells , 2007, Oncogene.

[18]  Anjanabha Saha,et al.  ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression , 2006, Nature.

[19]  T. Magnaldo,et al.  Nucleotide excision repair and related human diseases. , 2006, Genome dynamics.

[20]  N. Malats,et al.  Genetic Variation in the Nucleotide Excision Repair Pathway and Bladder Cancer Risk , 2006, Cancer Epidemiology Biomarkers & Prevention.

[21]  Jing Wang,et al.  The novel tumor suppressor p33ING2 enhances nucleotide excision repair via inducement of histone H4 acetylation and chromatin relaxation. , 2006, Cancer research.

[22]  R. Millikan,et al.  Polymorphisms in inflammation genes and bladder cancer: from initiation to recurrence, progression, and survival. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[23]  J. Gu,et al.  Nucleotide Excision Repair Gene Polymorphisms and Recurrence after Treatment for Superficial Bladder Cancer , 2005, Clinical Cancer Research.

[24]  Q. Wei,et al.  Nucleotide excision repair as a marker for susceptibility to tobacco‐related cancers: A review of molecular epidemiological studies , 2005, Molecular carcinogenesis.

[25]  Junying Yuan,et al.  The PHD Finger of the Chromatin-Associated Protein ING2 Functions as a Nuclear Phosphoinositide Receptor , 2003, Cell.

[26]  Jun-ichi Sawada,et al.  The Ubiquitin Ligase Activity in the DDB2 and CSA Complexes Is Differentially Regulated by the COP9 Signalosome in Response to DNA Damage , 2003, Cell.

[27]  F. Zolezzi,et al.  Basal transcriptional regulation of human damage-specific DNA-binding protein genes DDB1 and DDB2 by Sp1, E2F, N-myc and NF1 elements. , 2003, Nucleic acids research.

[28]  W. El-Deiry,et al.  BRCA1 Transcriptionally Regulates Damaged DNA Binding Protein (DDB2) In the DNA Repair Response Following UV-Irradiation , 2002, Cancer biology & therapy.

[29]  X. Wang,et al.  DNA damage-inducible gene p33ING2 negatively regulates cell proliferation through acetylation of p53 , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[30]  H. Jockusch,et al.  Assignment1 of homologous genes, Peli1/PELI1 and Peli2/PELI2, for the Pelle adaptor protein Pellino to mouse chromosomes 11 and 14 and human chromosomes 2p13.3 and 14q21, respectively, by physical and radiation hybrid mapping , 2001, Cytogenetic and Genome Research.

[31]  Jack A. Taylor,et al.  DNA repair gene XRCC1 polymorphisms, smoking, and bladder cancer risk. , 2001, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[32]  A. Saito,et al.  Cloning of a novel gene (ING1L) homologous to ING1, a candidate tumor suppressor , 1999, Cytogenetic and Genome Research.

[33]  P. Hanawalt,et al.  Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repair. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[34]  U. Francke,et al.  p48 Activates a UV-Damaged-DNA Binding Factor and Is Defective in Xeroderma Pigmentosum Group E Cells That Lack Binding Activity , 1998, Molecular and Cellular Biology.

[35]  S. Keeney,et al.  Chromosomal localization and cDNA cloning of the genes (DDB1 and DDB2) for the p127 and p48 subunits of a human damage-specific DNA binding protein. , 1995, Genomics.

[36]  H. Joenje,et al.  Genetic toxicology of oxygen. , 1989, Mutation research.

[37]  A. Kiltie Molecular epidemiology of DNA repair genes in bladder cancer. , 2009, Methods in molecular biology.

[38]  Jian Gu,et al.  Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer , 2009, Nature Genetics.

[39]  A. Kiltie,et al.  DNA double strand break repair in human bladder cancer is error prone and involves microhomology-associated end-joining. , 2004, Nucleic acids research.

[40]  H. Jockusch,et al.  Assignment of homologous genes, Peli1/PELI1 and Peli2/PELI2, for the Pelle adaptor protein Pellino to mouse chromosomes 11 and 14 and human chromosomes 2p13.3 and 14q21, respectively, by physical and radiation hybrid mapping. , 2001, Cytogenetics and cell genetics.

[41]  H. van Steeg The role of nucleotide excision repair and loss of p53 in mutagenesis and carcinogenesis. , 2001, Toxicology letters.

[42]  N. Dubrawsky Cancer statistics , 1989, CA: a cancer journal for clinicians.