Imaging of low- and intermediate-grade gliomas.

Imaging plays a crucial role in the diagnosis and management of low- and intermediate-grade gliomas. In this article, the traditional role of imaging studies in glioma patients and the appearance of some of the more common glial tumors on conventional computed tomography (CT) and magnetic resonance (MR) examinations are reviewed. The impact that MR spectroscopy and MR perfusion imaging have made on the evaluation patients after therapy for glial tumors also is reviewed.

[1]  T. H. Newton,et al.  Brain radiation lesions: MR imaging. , 1986, Radiology.

[2]  J. Parisi,et al.  Principles and practice of neuropathology , 2003 .

[3]  R. Kauppinen,et al.  Radiation-induced changes in human brain metabolites as studied by 1H nuclear magnetic resonance spectroscopy in vivo. , 1995, International journal of radiation oncology, biology, physics.

[4]  S. Bluml,et al.  Efficacy of Proton Magnetic Resonance Spectroscopy Inclinical Decision Making for Patients with Suspected Malignant Brain Tumors , 2004, Journal of Neuro-Oncology.

[5]  H. Hacker,et al.  Oligodendrogliomas: CT patterns with emphasis on features indicating malignancy. , 1979, Journal of computer assisted tomography.

[6]  R. Prayson,et al.  Protoplasmic astrocytoma. A clinicopathologic study of 16 tumors. , 1995, American journal of clinical pathology.

[7]  D. Eberhard,et al.  Pleomorphic xanthoastrocytoma, a distinctive astroglial tumor: neuroradiologic and pathologic features. , 1993, AJNR. American journal of neuroradiology.

[8]  D. Louis Collins,et al.  Accurate, noninvasive diagnosis of human brain tumors by using proton magnetic resonance spectroscopy , 1996, Nature Medicine.

[9]  W. Reddick,et al.  Clinical value of proton magnetic resonance spectroscopy for differentiating recurrent or residual brain tumor from delayed cerebral necrosis. , 1996, International journal of radiation oncology, biology, physics.

[10]  P. Burger,et al.  The morphologic effects of radiation administered therapeutically for intracranial gliomas.A Postmortem study of 25 cases , 1979, Cancer.

[11]  N. de Tribolet,et al.  Pilocytic cerebellar astrocytoma in adults: case report. , 1993, Surgical neurology.

[12]  M Takahashi,et al.  Correlation of MR imaging-determined cerebral blood volume maps with histologic and angiographic determination of vascularity of gliomas. , 1998, AJR. American journal of roentgenology.

[13]  Harlan I. Firminger,et al.  Atlas of tumor pathology , 1954 .

[14]  S Ekholm,et al.  Adverse effects of brain irradiation correlated with MR and CT imaging. , 1987, International journal of radiation oncology, biology, physics.

[15]  W. Paulus,et al.  Intratumoral histologic heterogeneity of gliomas. A quantitative study , 1989, Cancer.

[16]  Bruce R. Rosen,et al.  Echo-Planar MR Cerebral Blood Volume Mapping of Gliomas , 1995 .

[17]  G. Fuller,et al.  The significance of lack of MR contrast enhancement of supratentorial brain tumors in adults: histopathological evaluation of a series. , 1998, Surgical neurology.

[18]  R. Lenkinski,et al.  Proton MR Spectroscopy of Experimental Radiation‐Induced White Matter Injury , 1992, Journal of computer assisted tomography.

[19]  J E Heiserman,et al.  Effect of voxel position on single-voxel MR spectroscopy findings. , 2000, AJNR. American journal of neuroradiology.

[20]  P. Van Tassel,et al.  Intracranial oligodendrogliomas: imaging findings in 35 untreated cases. , 1989, AJR. American journal of roentgenology.

[21]  K. Plate,et al.  Angiogenesis in malignant gliomas , 1995, Glia.

[22]  C R Bird,et al.  Gliomas: classification with MR imaging. , 1990, Radiology.

[23]  Y. Olsson,et al.  Reliability of Computed Tomography in Assessing Histopathological Features of Malignant Supratentorial Gliomas , 1981, Journal of computer assisted tomography.

[24]  W P Dillon,et al.  Radiation injury of the brain. , 1991, AJNR. American journal of neuroradiology.

[25]  Pascale Varlet,et al.  Oligodendrogliomas. Part II: A new grading system based on morphological and imaging criteria , 1997, Journal of Neuro-Oncology.

[26]  S. Brem.  The role of vascular proliferation in the growth of brain tumors. , 1976, Clinical neurosurgery.

[27]  E F Halpern,et al.  Cerebral blood volume maps of gliomas: comparison with tumor grade and histologic findings. , 1994, Radiology.

[28]  J. Frahm,et al.  Noninvasive differentiation of tumors with use of localized H-1 MR spectroscopy in vivo: initial experience in patients with cerebral tumors. , 1989, Radiology.

[29]  S. Nelson,et al.  Serial evaluation of patients with brain tumors using volume MRI and 3D 1H MRSI , 1999, NMR in biomedicine.

[30]  J Hennig,et al.  Human brain tumors: assessment with in vivo proton MR spectroscopy. , 1993, Radiology.

[31]  S B Green,et al.  Patient age, histologic features, and length of survival in patients with glioblastoma multiforme , 1987, Cancer.