Improper Gaussian signaling (IGS) has shown its capability of improving the rate of interference-limited networks by exploiting the additional degrees of freedom in signal processing. This article considers a system of a multiple-input single-output (MISO) cellular network coexisting with device-to-device (D2D) communication, where the former employs proper Gaussian signaling (PGS) but the latter employs IGS to improve D2D’s rate and also to mitigate interference to the former. Both non-orthogonal and orthogonal bandwidth sharing between cellular users (CUs) and D2D pairs are considered. The problems of joint bandwidth allocation and signal beamforming to maximize the minimum CUs’ rate subject to the transmit power budget and D2D’s rate threshold are addressed, which pose critical computational challenges. Path-following algorithms of low complexity are developed for computational solutions. Two distinct scenarios, i.e., unmanned aerial vehicle (UAV)-enabled networks, and MISO cellular networks are simulated to give insight into the superiority of using IGS over PGS. Our results reveal that in UAV-enabled networks, orthogonal sharing produces a higher D2D’s rate, while non-orthogonal sharing offers better CUs’ rate under practical levels of D2D’s rate. In MISO systems, IGS is a game-changer, which enables the orthogonal sharing to uniformly outperform the non-orthogonal sharing in terms of CUs’ rate.