Oxidation of Recombinant Human Parathyroid Hormone: Effect of Oxidized Position on the Biological Activity

[1]  Toshiaki Watanabe,et al.  Comparative study of human-PTH(1-84) and human-PTH(1-34) in the chick hypercalcemia bioassay , 1994, Journal of Bone and Mineral Metabolism.

[2]  O. Tørring,et al.  The anabolic effects of human parathyroid hormone (hPTH) on rat vertebral body mass are also reflected in the quality of bone, assessed by biomechanical testing: a comparison study between hPTH-(1-34) and hPTH-(1-84). , 1991, Endocrinology.

[3]  H. Kronenberg,et al.  Expression of human parathyroid hormone-(1-84) in Escherichia coli as a factor X-cleavable fusion protein. , 1990, The Journal of biological chemistry.

[4]  L. Duong,et al.  The bovine renal parathyroid hormone (PTH) receptor has equal affinity for two different amino acid sequences: the receptor binding domains of PTH and PTH-related protein are located within the 14-34 region. , 1990, Endocrinology.

[5]  J. Zull,et al.  Effect of methionine oxidation and deletion of amino-terminal residues on the conformation of parathyroid hormone. Circular dichroism studies. , 1990, The Journal of biological chemistry.

[6]  B. Riggs,et al.  Bone Responsiveness to Parathyroid Hormone in Normal and Osteoporotic Postmenopausal Women , 1989 .

[7]  T. Tsushima,et al.  A highly sensitive bioassay for PTH using ROS 17/2.8 subclonal cells. , 1987, Acta endocrinologica.

[8]  T. Kimura,et al.  Biological activities of synthetic human parathyroid hormone (PTH) 1-84 relative to natural bovine 1-84 PTH in two different in vivo bioassay systems. , 1985, Endocrinology.

[9]  A. Frelinger,et al.  Oxidized forms of parathyroid hormone with biological activity. Separation and characterization of hormone forms oxidized at methionine 8 and methionine 18. , 1984, The Journal of biological chemistry.

[10]  G. Hendy,et al.  Complete amino acid sequence of human parathyroid hormone. , 1978, Biochemistry.

[11]  M. Yamamoto,et al.  Studies on soybean trypsin inhibitors. I. Purification and characterization of two soybean trypsin inhibitors. , 1978, Journal of biochemistry.

[12]  T. Koide,et al.  Studies on soybean trypsin inhibitors. II. Accidentally modified Kunitz soybean trypsin inhibitor. , 1971, Journal of biochemistry.

[13]  H. Keutmann,et al.  Isolation and chemical properties of porcine parathyroid hormone. , 1971, Biochemistry.

[14]  Y. Nabuchi,et al.  Peptide mapping of recombinant human parathyroid hormone by enzymatic digestion and subsequent fast-atom bombardment mass spectrometry. , 1995, Rapid communications in mass spectrometry : RCM.

[15]  H. Kronenberg,et al.  Parathyroid hormone: chemistry, biosynthesis, and mode of action. , 1982, Advances in protein chemistry.