A simple, precise, and sensitive HPLC method for quantification of letrozole in rat plasma: development, validation, and preclinical pharmacokinetics

[1]  Hatem A. Abuelizz,et al.  Evaluation of the pharmacokinetics of the simultaneous quantification of letrozole and palbociclib in rat plasma by a developed and validated HPLC–PDA , 2020, Acta Chromatographica.

[2]  P. Sengupta,et al.  Simultaneous quantification of abemaciclib and letrozole in rat plasma: method development, validation and pharmacokinetic application. , 2020, Biomedical chromatography : BMC.

[3]  S. Mutalik,et al.  Full Factorial Experimental Design for Development and Validation of a RP-HPLC Method for Estimation of Letrozole in Nanoformulations , 2017 .

[4]  S. Mutalik,et al.  Preclinical pharmacokinetics and biodistribution studies of asenapine maleate using novel and sensitive RP-HPLC method. , 2017, Bioanalysis.

[5]  Prarthana V. Rewatkar,et al.  Peptide dendrimer‐conjugates of ketoprofen: Synthesis and ex vivo and in vivo evaluations of passive diffusion, sonophoresis and iontophoresis for skin delivery , 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[6]  J. Stone.  Sample preparation techniques for mass spectrometry in the clinical laboratory , 2017 .

[7]  Jaivik V. Shah,et al.  SPE–UPLC–MS/MS assay for determination of letrozole in human plasma and its application to bioequivalence study in healthy postmenopausal Indian women☆ , 2016, Journal of pharmaceutical analysis.

[8]  Dietrich A. Volmer,et al.  Recent advances in sample preparation techniques to overcome difficulties encountered during quantitative analysis of small molecules from biofluids using LC-MS/MS. , 2014, The Analyst.

[9]  B. Panda,et al.  Development of a High-Performance Liquid Chromatographic Method for Determination of Letrozole in Wistar Rat Serum and its Application in Pharmacokinetic Studies , 2012, Scientia pharmaceutica.

[10]  G. Higa.  Letrozole in Postmenopausal Hormone-Responsive Early-Stage Breast Cancer , 2012, Drugs.

[11]  A. Brodie,et al.  Aromatase, aromatase inhibitors, and breast cancer , 2011, The Journal of Steroid Biochemistry and Molecular Biology.

[12]  C. Joshi,et al.  VALIDATION AND APPLICATION OF A HIGH­PERFORMANCE LIQUID CHROMATOGRAPHY- TANDEM MASS SPECTROMETRY ASSAY FOR LETROZOLE IN HUMAN PLASMA , 2011 .

[13]  S. Sen,et al.  Reverse Phase High Performance Liquid Chromatographic Method for the Analysis of Letrozole in Pharmaceutical Dosage Forms , 2008, Indian journal of pharmaceutical sciences.

[14]  S. Ganguly,et al.  A VALIDATED UV SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF LETROZOLE IN BULK AND SOLID DOSAGE FORM , 2008 .

[15]  A. Zarghi,et al.  HPLC Determination of Letrozole in Plasma Using Fluorescence Detection: Application to Pharmacokinetic Studies , 2007 .

[16]  S. K. Ghosal,et al.  Development and validation of a spectrophotometric method for estimation of letrozole in bulk and pharmaceutical formulation. , 2007, Die Pharmazie.

[17]  M. Wempe,et al.  Pharmacokinetics of letrozole in male and female rats: influence of complexation with hydroxybutenyl‐β‐cyclodextrin , 2007, The Journal of pharmacy and pharmacology.

[18]  S. Keam,et al.  Letrozole : in postmenopausal hormone-responsive early-stage breast cancer. , 2006, Drugs.

[19]  M. Thevis,et al.  Identification of the aromatase inhibitor letrozole in urine by gas chromatography/mass spectrometry. , 2005, Rapid communications in mass spectrometry : RCM.

[20]  D. Tripathy,et al.  Aromatase inhibitors: rationale and use in breast cancer. , 2005, Annual review of medicine.

[21]  A. M. Contento,et al.  Determination of drugs used in advanced breast cancer by capillary gas chromatography of pharmaceutical formulations , 2003 .

[22]  Hilde van der Togt,et al.  Publisher's Note , 2003, J. Netw. Comput. Appl..

[23]  R. Brueggemeier.  Aromatase, Aromatase Inhibitors, and Breast Cancer , 2001, American journal of therapeutics.

[24]  M. Marina,et al.  CHROMATOGRAPHY: LIQUID | Micellar Liquid Chromatography , 2000 .

[25]  A. Sioufi,et al.  High-performance liquid chromatography of the aromatase inhibitor, letrozole, and its metabolite in biological fluids with automated liquid-solid extraction and fluorescence detection. , 1996, Journal of chromatography. B, Biomedical applications.

[26]  D. Gygax,et al.  Development, application and comparison of an enzyme immunoassay and a high-performance liquid chromatography method for the determination of the aromatase inhibitor CGS 20,267 in biological fluids. , 1994, Journal of pharmaceutical sciences.