PRMT5 inhibition modulates E2F1 methylation and gene regulatory networks leading to therapeutic efficacy in JAK2V617F mutant MPN.
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K. Helin | R. Koche | R. Levine | J. Maag | A. Pastore | N. Bhagwat | P. Scherle | A. Radzisheuskaya | A. Karzai | K. Vaddi | A. Viny | R. Rampal | W. Xiao | B. Durham | Stephanie Braunstein | F. Pastore | A. Krishnan | K. Cordner | Anouar Zouak | Alexander Grego | Jaanvi Mehta | Min Wang | Hong Lin | Young C. Park | Wenbin Xiao | Bing Li | Robert L Bownan | S. Braunstein | R. Levine