FROM COMPLEX SIGNAL TO ADAPTED BEHAVIOR A THEORETICAL APPROACH OF THE HONEYBEE OLFACTORY BRAIN

The honeybee olfactory pathway is an attractive system for modeling: it is relatively simple, and it is well described functionally and morphologically. Moreover, due to the conservation of the olfactory structure through phylogeny, models may bring information of generic interest. From the point of view of behavior, this system has the ability of encoding the sensory messages into stable representations, and extracting key features from them. The neural bases of these mechanisms are still largely unknown; the purpose of the present paper is to present three different models of the same system, which make use of the same corpus of morphological and electrophysiological data, but which incorporate these data with different levels of details. We show the interrelations between these models and the specific contribution of each of them to the modeling of the olfactory pathway. We show that the design of the simplest model capitalized on the results of the previous ones, and that it suggests mechanisms for simultaneous generation of stable internal representations and key feature extraction.

[1]  D. Schild,et al.  Principles of odor coding and a neural network for odor discrimination. , 1988, Biophysical journal.

[2]  Michael E. Hasselmo,et al.  Acetylcholine and Learning in a Cortical Associative Memory , 1993, Neural Computation.

[3]  Claudine Masson,et al.  Behavioural discrimination of oilseed rape volatiles by the honeybee Apis mellifera L. , 1993 .

[4]  Claudine Masson,et al.  Towards a cognitive understanding of odor discrimination: Combining experimental and theoretical approaches , 1995, Behavioural Processes.

[5]  B. Smith,et al.  A computational model of the response of honey bee antennal lobe circuitry to odor mixtures: overshadowing, blocking and unblocking can arise from lateral inhibition , 1997, Behavioural Brain Research.

[6]  G. Nicolas,et al.  Distribution régionale de l'incorporation du [3H] 2-désoxyglucose dans le lobe antennaire de l'ouvrière d'abeille , 1993 .

[7]  Glenn D. Prestwich,et al.  Chemical studies of pheromone receptors in insects , 1993 .

[8]  C. Masson,et al.  Biochemical characterization, molecular cloning and localization of a putative odorant‐binding protein in the honey bee Apis mellifera L. (Hymenoptera: Apidea) , 1997, FEBS letters.

[9]  Linda B. Buck,et al.  Information coding in the olfactory system: Evidence for a stereotyped and highly organized epitope map in the olfactory bulb , 1994, Cell.

[10]  J. Cornuet,et al.  Honeybees have putative olfactory receptor proteins similar to those of vertebrates. , 1994, Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie.

[11]  Christiane Linster,et al.  Odor Processing in the Bee: A Preliminary Study of the Role of Central Input to the Antennal Lobe , 1993, NIPS.

[12]  R. Menzel,et al.  Representations of odours and odour mixtures visualized in the honeybee brain , 1997, Nature.

[13]  G. Shepherd,et al.  Mechanisms of olfactory discrimination: converging evidence for common principles across phyla. , 1997, Annual review of neuroscience.

[14]  R. Axel,et al.  A novel multigene family may encode odorant receptors: A molecular basis for odor recognition , 1991, Cell.

[15]  J S Kauer,et al.  Salamander olfactory bulb neuronal activity observed by video rate, voltage-sensitive dye imaging. III. Spatial and temporal properties of responses evoked by odorant stimulation. , 1995, Journal of neurophysiology.

[16]  John S. Kauer,et al.  Contributions of topography and parallel processing to odor coding in the vertebrate olfactory pathway , 1991, Trends in Neurosciences.

[17]  X. Sun,et al.  Morphology and spatial distribution of bee antennal lobe interneurones responsive to odours , 1993 .

[18]  B. Quenet,et al.  A DYNAMIC MODEL OF KEY FEATURE EXTRACTION : THE EXAMPLE OF OLFACTION II-Theoretical analysis by a Boltzmann-type distribution of attractors , 1997 .

[19]  C. Masson,et al.  Bases cellulaires et moléculaires de la discrimination des odeurs à signification biologique chez les insectes , 1995 .

[20]  J. Zwiller.  Cell biology of olfaction, AI Farbman. Cambridge University Press, New York (1992), 1 vol, 282 p , 1993 .

[21]  J. Royet,et al.  Specificity of spatial patterns of glomerular activation in the mouse olfactory bulb: computer-assisted image analysis of 2-deoxyglucose autoradiograms , 1987, Brain Research.

[22]  G. Laurent.  Dynamical representation of odors by oscillating and evolving neural assemblies , 1996, Trends in Neurosciences.

[23]  J S Kauer,et al.  Salamander olfactory bulb neuronal activity observed by video rate, voltage-sensitive dye imaging. I. Characterization of the recording system. , 1995, Journal of neurophysiology.

[24]  Joel L. Davis,et al.  Olfaction: A Model System for Computational Neuroscience , 1991 .

[25]  Richard Axel,et al.  Topographic organization of sensory projections to the olfactory bulb , 1994, Cell.

[26]  Christiane Linster,et al.  A Neural Model of Olfactory Sensory Memory in the Honeybee's Antennal Lobe , 1996, Neural Computation.

[27]  W. Getz,et al.  A test of identified response classes among olfactory receptor neurons in the honey-bee worker , 1992 .

[28]  M. Hasselmo,et al.  Modulation of inhibition in a model of olfactory bulb reduces overlap in the neural representation of olfactory stimuli , 1997, Behavioural Brain Research.

[29]  D. T. Jones,et al.  Golf: an olfactory neuron specific-G protein involved in odorant signal transduction. , 1989, Science.

[30]  D. Malun,et al.  Inventory and distribution of synapses of identified uniglomerular projection neurons in the antennal lobe of Periplaneta americana , 1991, The Journal of comparative neurology.

[31]  J. Rospars,et al.  Coding of odour quality: roles of convergence and inhibition , 1994 .

[32]  P. Peretto.  An introduction to the modeling of neural networks , 1992 .

[33]  X. Sun,et al.  Odour quality processing by bee antennal lobe interneurones , 1993 .

[34]  Claudine Masson,et al.  Isolation and identification of volatile constituents of sunflowers (Helianthus annuus L.) , 1984 .

[35]  H. Mustaparta.  Chemical information processing in the olfactory system of insects. , 1990, Physiological reviews.