TOXICITY REVIEW FOR IODOTRIFLUOROMETHANE (CF3I)

In 1987, 23 countries, including the United States, signed an agreement that would reduce the production of ozone-depleting substances (ODS). Amendments to this agreement, called the “Montreal Protocol on Substances that Deplete the Ozone Layer,” have placed controls on the production and consumption of ozone-depleting materials, including the fire suppressants, Halon 121 1 and Halon 1301. These compounds are effective and. when used correctly, they have acceptable risk. They have, however, been identified as ozone-depleting substances. This ban has forced a search for suitable replacements for Halon 121 1 and Halon 1301. which are both effective and safe, as well as environmentally acceptable. A number of candidate replacement agents for Halon 1301 have been tested for efficacy and safety and are currently in use. Another candidate replacement is CF3I (iodotrifluoromethane, trifluoroiodomethane, trifluoromethyl iodide). A request for a Toxicology Profile for CFiI was submitted by the Army Acquisition Pollution Prevention Support Office of the Army Materiel Command.