Contrast sensitivity in one-eyed subjects

The effects of early monocular form deprivation on the developing mammalian visual system, and the anatomical and physiological consequences of early monocular enucleation, suggest that the remaining eye of human subjects who had the other eye removed early during development might be capable of supernormal performance. To test this inference, the achromatic contrast sensitivity of the remaining eye of subjects who had the other eye removed at different ages after birth was compared with that of normal subjects tested under monocular and binocular conditions. The results show that all subjects who had an eye removed during early development had a higher contrast sensitivity than the better eye of control subjects. Furthermore, the earlier in development that the eye was removed, the lower the spatial frequency at which contrast sensitivity is enhanced compared with measurements made in the better eye of control subjects, and the larger the range of spatial frequencies over which contrast sensitivity is supernormal.

[1]  Charles Samuel Harris,et al.  Visual coding and adaptability , 1980 .

[2]  H. B. Barlow,et al.  Visual experience and cortical development , 1975, Nature.

[3]  J. Lund,et al.  Modified optic projections after unilateral eye removal in young rats. , 1973, Brain, behavior and evolution.

[4]  S. R. Lehky.  An Astable Multivibrator Model of Binocular Rivalry , 1988, Perception.

[5]  Robert F. Hess,et al.  Vision: The puzzle of amblyopia , 1991 .

[6]  L. Maffei,et al.  Functional organization of the cat's visual cortex after prenatal interruption of binocular interactions. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[7]  L. Maffei,et al.  Response properties in the dorsal lateral geniculate nucleus of the adult cat after interruption of prenatal binocular interactions. , 1989, Journal of neurophysiology.

[8]  G. Poggio,et al.  Stereoscopic mechanisms in monkey visual cortex: binocular correlation and disparity selectivity , 1988, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[9]  Shrinkage of cells in undeprived laminae of the monkey lateral geniculate nucleus following late closure of one eye , 1981, Brain Research.

[10]  Jidi Majia,et al.  Contrast , 1908, The Fairchild Books Dictionary of Fashion.

[11]  P. Rakic,et al.  Regulation of axon number in primate optic nerve by prenatal binocular competition , 1983, Nature.

[12]  Vaegan,et al.  Critical period for deprivation amblyopia in children. , 1979, Transactions of the ophthalmological societies of the United Kingdom.

[13]  N. Logothetis,et al.  Role of the color-opponent and broad-band channels in vision , 1990, Visual Neuroscience.

[14]  N. V. Swindale,et al.  Recovery from monocular deprivation in the monkey. III. Reversal of anatomical effects in the visual cortex , 1981, Proceedings of the Royal Society of London. Series B. Biological Sciences.

[15]  S. Bisti,et al.  Visual performance in behaving cats after prenatal unilateral enucleation. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[16]  P. Rakic.  Mechanism of ocular dominance segregation in the lateral geniculate nucleus: competitive elimination hypothesis , 1986, Trends in Neurosciences.

[17]  E. Polley,et al.  The topography of ganglion cell production in the cat's retina , 1985, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[18]  Colin Blakemore,et al.  Vision: Coding and Efficiency , 1991 .

[19]  D. Teller,et al.  Development of contrast sensitivity in infant Macaca nemestrina monkeys. , 1980, Science.

[20]  P. Rakic,et al.  Development of visual centers in the primate brain depends on binocular competition before birth. , 1981, Science.

[21]  R. Freeman,et al.  Monocularly deprived humans: nondeprived eye has supernormal vernier acuity. , 1980, Journal of neurophysiology.

[22]  M S Banks,et al.  Acuity and contrast sensitivity in 1-, 2-, and 3-month-old human infants. , 1978, Investigative ophthalmology & visual science.

[23]  R W Guillery,et al.  Age-related fiber order in the optic tract of the ferret , 1985, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[24]  D. Hubel,et al.  The development of ocular dominance columns in normal and visually deprived monkeys , 1980, The Journal of comparative neurology.

[25]  D. Hubel,et al.  Plasticity of ocular dominance columns in monkey striate cortex. , 1977, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[26]  G. B. Wetherill,et al.  SEQUENTIAL ESTIMATION OF POINTS ON A PSYCHOMETRIC FUNCTION. , 1965, The British journal of mathematical and statistical psychology.

[27]  C Blakemore,et al.  Effects of visual deprivation on the development of the monkey's lateral geniculate nucleus. , 1986, The Journal of physiology.

[28]  R. Guillery,et al.  Changing glial organization relates to changing fiber order in the developing optic nerve of ferrets , 1987, The Journal of comparative neurology.

[29]  C. Blakemore,et al.  Recovery from monocular deprivation in the monkey. I. Reversal of physiological effects in the visual cortex , 1981, Proceedings of the Royal Society of London. Series B. Biological Sciences.

[30]  S. McKee,et al.  Improvement in vernier acuity with practice , 1978, Perception & psychophysics.

[31]  T. Mueller.  A physiological model of binocular rivalry , 1990, Visual Neuroscience.

[32]  J. Lund,et al.  A quantitative investigation of spine and dendrite development of neurons in visual cortex (area 17) of Macaca nemestrina monkeys , 1979, The Journal of comparative neurology.

[33]  J. G. Parnavelas,et al.  Making of the nervous system. , 1986, Nature.

[34]  Janette Atkinson,et al.  Development of contrast sensitivity over the first 3 months of life in the human infant , 1977, Vision Research.

[35]  J. Provis,et al.  Human fetal optic nerve: Overproduction and elimination of retinal axons during development , 1985, The Journal of comparative neurology.

[36]  J Atkinson,et al.  Contrast sensitivity function of preschool children. , 1981, The British journal of ophthalmology.

[37]  R. Guillery,et al.  Behavioral, electrophysiological and morphological studies of binocular competition in the development of the geniculo–corticalpathways of cats , 1974, The Journal of comparative neurology.

[38]  H. Ono,et al.  Vernier acuity in monocular and binocular children , 1992 .

[39]  R. B. Post,et al.  Monocular deprivation in humans: a study of identical twins. , 1982, Investigative ophthalmology & visual science.

[40]  T. Powell,et al.  Cell sizes in the lateral geniculate nucleus of normal infant and adult rhesus monkeys , 1981, Brain Research.

[41]  M S Banks,et al.  Infant pattern vision: a new approach based on the contrast sensitivity function. , 1981, Journal of experimental child psychology.

[42]  JANETTE ATKINSON,et al.  Acuity and contrast sensivity of infant vision , 1974, Nature.

[43]  A. Cowey,et al.  Fibre organization of the monkey's optic tract: I. Segregation of functionally distinct optic axons , 1990, The Journal of comparative neurology.

[44]  L. Chalupa,et al.  Organization of geniculocortical connections following prenatal interruption of binocular interactions. , 1986, Brain research.

[45]  C. Blakemore,et al.  The physiological effects of monocular deprivation and their reversal in the monkey's visual cortex. , 1978, The Journal of physiology.

[46]  C Blakemore,et al.  Sensitive and vulnerable periods in the development of the visual system. , 1991, Ciba Foundation symposium.